Dual electrode system for a continuous analyte sensor
First Claim
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1. A glucose sensor system configured for insertion into a host for measuring a glucose concentration in the host, the system comprising:
- a sensor comprising a first working electrode and a second working electrode, wherein the first working electrode is configured to generate a first signal associated with glucose and non-glucose related electroactive compounds, the glucose and non-glucose related electroactive compounds having a first oxidation potential;
wherein the non-glucose related electroactive compounds with an oxidation potential that substantially overlaps with the first oxidation potential, and wherein the first working electrode and the second working electrode are configured and arranged about a central longitudinal axis along an overlapping length of the sensor such that the central longitudinal axis passes through each of the working electrodes; and
electronics operably connected to the first working electrode and the second working electrode and configured to process the first signal and the second signal to generate a glucose concentration substantially without signal contribution due to in vivo mechanical factors.
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Abstract
Disclosed herein are systems and methods for a continuous analyte sensor, such as a continuous glucose sensor. One such system utilizes first and second working electrodes to measure additional analyte or non-analyte related signal. Such measurements may provide a background and/or sensitivity measurement(s) for use in processing sensor data and may be used to trigger events such as digital filtering of data or suspending display of data.
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Citations
51 Claims
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1. A glucose sensor system configured for insertion into a host for measuring a glucose concentration in the host, the system comprising:
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a sensor comprising a first working electrode and a second working electrode, wherein the first working electrode is configured to generate a first signal associated with glucose and non-glucose related electroactive compounds, the glucose and non-glucose related electroactive compounds having a first oxidation potential;
wherein the non-glucose related electroactive compounds with an oxidation potential that substantially overlaps with the first oxidation potential, and wherein the first working electrode and the second working electrode are configured and arranged about a central longitudinal axis along an overlapping length of the sensor such that the central longitudinal axis passes through each of the working electrodes; andelectronics operably connected to the first working electrode and the second working electrode and configured to process the first signal and the second signal to generate a glucose concentration substantially without signal contribution due to in vivo mechanical factors. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22)
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23. An analyte sensor system configured for insertion into a host for measuring an analyte in the host, the system comprising:
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a continuous analyte sensor comprising a first working electrode and a second working electrode, wherein the first working electrode is disposed beneath an active enzymatic portion of a membrane;
wherein the second working electrode is disposed beneath an inactive-enzymatic or non-enzymatic portion of a membrane, and wherein the first working electrode and the second working electrode are configured to measure-interfering biochemical species such that signal contribution associated with the interfering biochemical species can be substantially removed continuously for a time period, wherein the time period is between about a few hours and about 10 days; andelectronics operably connected to the first working electrode and the second working electrode, and configured to process the first signal and the second signal to generate continuous sensor analyte data substantially without signal contribution due the biochemical species for said time period. - View Dependent Claims (24, 25, 26, 27, 28, 29, 30, 31, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51)
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32. The system of elaim 29, wherein a surface area of at least one of the reference electrode and the counter electrode is at least six times a surface area of at least one of the first working electrode and the second working electrode.
Specification