Continuous spectroscopic measurement of total hemoglobin
First Claim
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1. An apparatus for measuring total hemoglobin of whole blood, comprising:
- a catheter;
a light source configured to emit light at multiple wavelengths;
a transmit optical fiber positioned within the catheter, the transmit optical fiber having a proximal end configured to receive the light from the light source and a distal end configured to be in communication with whole blood;
a receive optical fiber positioned within the catheter, the receive optical fiber having a proximal end and a distal end configured to receive reflected light from the whole blood;
a detector positioned at the proximal end of the receive optical fiber, the detector configured to measure a change in light absorbance of the reflected light between multiple wavelengths; and
a processing unit configured to measure total hemoglobin of the whole blood using the change in light absorbance of the reflected light between multiple wavelengths in proportion to a difference between the wavelengths.
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Abstract
Methods for measuring the total hemoglobin of whole blood include measuring reflective light at multiple wavelengths within the visible spectrum, calculating light absorbance at each of the multiple wavelengths, performing a comparison in a change in like absorbance between the multiple wavelengths, and/or relating the comparison to total hemoglobin. A system for measuring total hemoglobin of whole blood may include at least one light source, a catheter, optical fibers, at least one photodetector, data processing circuitry, and/or a display unit.
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Citations
22 Claims
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1. An apparatus for measuring total hemoglobin of whole blood, comprising:
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a catheter; a light source configured to emit light at multiple wavelengths; a transmit optical fiber positioned within the catheter, the transmit optical fiber having a proximal end configured to receive the light from the light source and a distal end configured to be in communication with whole blood; a receive optical fiber positioned within the catheter, the receive optical fiber having a proximal end and a distal end configured to receive reflected light from the whole blood; a detector positioned at the proximal end of the receive optical fiber, the detector configured to measure a change in light absorbance of the reflected light between multiple wavelengths; and a processing unit configured to measure total hemoglobin of the whole blood using the change in light absorbance of the reflected light between multiple wavelengths in proportion to a difference between the wavelengths. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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12. An apparatus for determining total hemoglobin of whole blood, comprising:
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a light source configured to emit light at multiple wavelengths in the visible spectrum into whole blood; a photodetector configured to receive the light from the whole blood; and a processing unit coupled to the photodetector for determining light absorbance of the light from the whole blood at each of the multiple wavelengths and for determining total hemoglobin of whole blood using a change in the light absorbance between the multiple wavelengths in proportion to a difference between the wavelengths. - View Dependent Claims (13, 14, 15, 16, 17, 18, 19, 20, 21, 22)
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Specification