Optical image pickup apparatus for imaging living body tissue

• US 7,427,747 B2
• Filed: 07/27/2006
• Issued: 09/23/2008
• Est. Priority Date: 05/16/2003
• Status: Expired due to Fees

• Current Assignee: Olympus Corporation
• Original Assignee: Olympus Corporation
• Inventors: Hirata, Tadashi, Ishihara, Yasushige, Xie, Tianyu, Okawa, Atsushi, Tosaka, Hiroshi, Tokuda, Kazunari, Horii, Akihiro
• Primary Examiner(s): YAM, STEPHEN K
• Application Number:
  US11/494,184
• Publication Number:
  US 20060261263A1
• Time in Patent Office: 789 Days
• Field of Search: 250/205, 250/230, 250/234, 250/235, 250/559.22, 356/237.2, 356/237.4, 356/237.5, 356/600, 356/602, 359/146, 359/147
• US Class Current: 250/234
• CPC Class Codes: A61B 1/0008 characterised by distal tip features
• CPC Class Codes: A61B 1/00096 Optical elements
• CPC Class Codes: A61B 1/00165 with light-conductive means, e.g. fibre optics A61B1/07 takes precedence
• CPC Class Codes: A61B 1/00172 with means for scanning
• CPC Class Codes: A61B 1/00183 for variable viewing angles
• CPC Class Codes: A61B 1/00188 with focusing or zooming features
• CPC Class Codes: A61B 1/04 combined with photographic or television appliances
• CPC Class Codes: A61B 1/07 using light-conductive means, e.g. optical fibres
• CPC Class Codes: G02B 21/0032 Optical details of illumination, e.g. light-sources, pinholes, beam splitters, slits, fibers G02B21/0036 - G02B21/008; means for illumination of specimens in general G02B21/06
• CPC Class Codes: G02B 21/0036 Scanning details, e.g. scanning stages

Abstract

A control portion of an optical image pickup apparatus includes a scan driver, a lock-in amplifier, and an A/D converter. The scan driver outputs a predetermined drive signal to a Y-scanning mirror and an X-scanning mirror and scans the Y-scanning mirror and the X-scanning mirror. The lock-in amplifier detects a signal level Vout of a frequency component of the drive signal of the scan driver among signals detected by a detector portion. The A/D converter converts a signal detected by a detector portion and a signal level of the detected signal of a frequency component of a drive signal detected by the lock-in amplifier to digital signals and outputs the digital signals to an image processor. Thus, mirror scan operations of the scanning mirrors can be securely detected.

Claims

1. An optical image pickup apparatus, comprising:

at least one light source;

a probe having at least one optical scanning means for scanning light emitted from the light source to a target;

waveform signal generating means for generating a drive waveform for driving the optical scanning means;

an optical system including first light transmitting means for irradiating light from the light source to the target and first optical detecting means for receiving return light from the target;

image creating means for converting the first light from the optical system to electric signals and creating images;

scanning permit generating means for generating a scanning permit signal for permitting driving of the optical scanning means;

scanning state detecting means for detecting a scanning state signal indicating a driving state of the optical scanning means; and

light source output control means for generating a light source output control signal and controlling the light source as far as all of the scanning permit signal and scanning state signal are valid;

wherein the probe has a probe connection connector removably connected to the signal generating means, and connection detecting means for detecting a connection state of the probe connection connector and generating a connection detection signal.

2. An optical image pickup apparatus according to claim 1, wherein the scanning state detecting means includes:

scanning frequency detecting means for detecting a scanning frequency of the optical scanning means; and

scanning width detecting means for detecting a scanning width of the optical scanning means,

wherein, when the scanning frequency and/or the scanning width are equal to or lower than a predetermined value (predetermined values), the scanning state signal is invalid.

3. An optical image pickup apparatus according to claim 1,

wherein the scanning permit signal includes a drive waveform output permit signal, which is generated by the waveform signal generating means, for permitting output of the drive waveform and a light source output permit signal, which is generated from a light source output permit control means for controlling output of the light source,

wherein, when all of the drive waveform output permit signal and light source output permit signal are valid, the scanning permit signal is valid.

4. An optical image pickup apparatus according to claim 1,

wherein the optical scanning means is a scanning mirror.

5. An optical image pickup apparatus according to claim 1, wherein the scanning state detecting means has form change detecting means for detecting a change in form of a movable part of the optical scanning means.

6. An optical image pickup apparatus according to claim 4, wherein the scanning state detecting means has electrostatic capacitance detecting means for detecting a change in electrostatic capacitance due to driving of the optical scanning means.

7. An optical image pickup apparatus according to claim 4, wherein the scanning minor is a micromachine mirror produced in a semiconductor process.

8. An optical image pickup apparatus according to claim 1, wherein at least a part of the scanning state detecting means is integrated with the optical scanning means.

9. An optical image pickup apparatus according to claim 1, wherein the probe has a flexible insert portion having a small diameter.

10. An optical image pickup apparatus according to claim 1, wherein the probe has a confocal optical system.

11. An optical image pickup apparatus comprising:

at least one light source;

a probe having at least one optical scanning means for scanning light emitted from the light source to a target;

waveform signal generating means for generating a drive waveform for driving the optical scanning means;

an optical system including first light transmitting means for irradiating light from the light source to the target and first optical detecting means for receiving return light from the target;

image creating means for converting the first light from the optical system to electric signals and creating images;

scanning permit generating means for generating a scanning permit signal for permitting driving of the optical scanning means;

scanning state detecting means for detecting a scanning state signal indicating a driving state of the optical scanning means; and

light source output control means for generating a light source output control signal and controlling the light source as far as all of the scanning permit signal and scanning state signal are valid;

wherein the scanning state detecting means includes;

scanning frequency detecting means for detecting a scanning frequency of the optical scanning means; and

scanning width detecting means for detecting a scanning width of the optical scanning means,

wherein, when the scanning frequency and/or the scanning width are equal to or lower than a predetermined value (predetermined values), the scanning state signal is invalid.

12. An optical image pickup apparatus comprising:

at least one light source;

a probe having at least one optical scanning means for scanning light emitted from the light source to a target;

waveform signal generating means for generating a drive waveform for driving the optical scanning means;

an optical system including first light transmitting means for irradiating light from the light source to the target and first optical detecting means for receiving return light from the target;

image creating means for converting the first light from the optical system to electric signals and creating images;

scanning permit generating means for generating a scanning permit signal for permitting driving of the optical scanning means;

scanning state detecting means for detecting a scanning state signal indicating a driving state of the optical scanning means; and

light source output control means for generating a light source output control signal and controlling the light source as far as all of the scanning permit signal and scanning state signal are valid;

wherein the scanning permit signal includes a drive waveform output permit signal, which is generated by the waveform signal generating means, for permitting output of the drive waveform and a light source output permit signal, which is generated from a light source output permit control means for controlling output of the light source,

wherein, when all of the drive waveform output permit signal and light source output permit signal are valid, the scanning permit signal is valid.

13. An optical image pickup apparatus comprising:

at least one light source;

a probe having at least one optical scanning means for scanning light emitted from the light source to a target;

waveform signal generating means for generating a drive waveform for driving the optical scanning means;

an optical system including first light transmitting means for irradiating light from the light source to the target and first optical detecting means for receiving return light from the target;

image creating means for converting the first light from the optical system to electric signals and creating images;

scanning permit generating means for generating a scanning permit signal for permitting driving of the optical scanning means;

scanning state detecting means for detecting a scanning state signal indicating a driving state of the optical scanning means; and

light source output control means for generating a light source output control signal and controlling the light source as far as all of the scanning permit signal and scanning state signal are valid;

wherein the scanning state detecting means has form change detecting means for detecting a change in form of a movable part of the optical scanning means.

14. An optical image pickup apparatus comprising:

at least one light source;

a probe having at least one optical scanning means for scanning light emitted from the light source to a target;

waveform signal generating means for generating a drive waveform for diving the optical scanning means;

an optical system including first light transmitting means for irradiating light from the light source to the target and first optical detecting means for receiving return light from the target;

image creating means for converting the first light from the optical system to electric signals and creating images;

scanning permit generating means for generating a scanning permit signal for permitting driving of the optical scanning means;

scanning state detecting means for detecting a scanning state signal indicating a driving state of the optical scanning means; and

light source output control means for generating a light source output control signal and controlling the light source as far as all of the scanning permit signal and scanning state signal are valid;

wherein the optical scanning means is a scanning mirror and the scanning state detecting means has electrostatic capacitance detecting means for detecting a change in electrostatic capacitance due to driving of the optical scanning means.