Antiviral phosphonate analogs
First Claim
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1. A method for inhibiting hepatitis C virus in vitro comprising contacting a sample in need of such treatment with a conjugate or a pharmaceutically acceptable salt or solvate thereof wherein the conjugate is a compound of formula:
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[DRUG]-(A0)nn wherein;
DRUG is a compound of formula 511;
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Abstract
The invention is related to phosphorus substituted compounds with antiviral activity, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.
49 Citations
20 Claims
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1. A method for inhibiting hepatitis C virus in vitro comprising contacting a sample in need of such treatment with a conjugate or a pharmaceutically acceptable salt or solvate thereof wherein the conjugate is a compound of formula:
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[DRUG]-(A0)nnwherein; DRUG is a compound of formula 511; - View Dependent Claims (3, 4, 5, 6, 7, 8, 9, 10, 11)
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2. A method of inhibiting hepatitis C virus in an animal, comprising administering an effective amount of a conjugate or a pharmaceutically acceptable salt or solvate thereof, to the animal wherein the conjugate is a compound of formula:
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[DRUG]-(A0)nnwherein; DRUG is a compound of formula 511; - View Dependent Claims (12, 13, 14, 15, 16, 17, 18, 19, 20)
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Specification