Full field mammography with tissue exposure control, tomosynthesis, and dynamic field of view processing

• US 7,430,272 B2
• Filed: 10/16/2006
• Issued: 09/30/2008
• Est. Priority Date: 11/27/2002
• Status: Expired due to Term

• Current Assignee: Hologic Incorporated
• Original Assignee: Hologic Incorporated
• Inventors: Jing, Zhenxue, Smith, Andrew, Stein, Jay A., Kennedy, Donald, Hitzke, Georgia
• Primary Examiner(s): KAO, CHIH CHENG G
• Application Number:
  US11/582,061
• Publication Number:
  US 20070030949A1
• Time in Patent Office: 715 Days
• Field of Search: 378/21, 378/22, 378/27, 378/37
• US Class Current: 378/37
• CPC Class Codes: A61B 6/025 Tomosynthesis
• CPC Class Codes: A61B 6/06 Diaphragms
• CPC Class Codes: A61B 6/4035 the source being combined with a filter or grating
• CPC Class Codes: A61B 6/4291 the detector being combined with a grid or grating
• CPC Class Codes: A61B 6/482 involving multiple energy imaging
• CPC Class Codes: A61B 6/502 for diagnosis of breast, i.e. mammography

Abstract

A mammography system using a tissue exposure control relying on estimates of the thickness of the compressed and immobilized breast and of breast density to automatically derive one or more technic factors. The system further uses a tomosynthesis arrangement that maintains the focus of an anti-scatter grid on the x-ray source and also maintains the field of view of the x-ray receptor. Finally, the system finds an outline that forms a reduced field of view that still encompasses the breast in the image, and uses for further processing, transmission or archival storage the data within said reduced field of view.

Claims

1. A tomosynthesis mammography method comprising:

immobilizing a patient'"'"'s breast between compression surfaces that in turn are between a source of x-rays and an x-ray imaging receptor, said source having a focal spot from which it selectively emits x-rays toward the receptor;

selectively providing an anti-scatter grid that is retractable so that it can be removed from a space between the source of x-rays and the x-ray imaging receptor;

moving each of the source and the receptor to more than two different positions relative to the compression surfaces and the patient'"'"'s breast while the breast remains immobilized;

emitting, at each of said positions, x-rays from the source that pass through the breast and impinge on the receptor;

deriving, from the receptor, information related to respective two dimensional projection x-ray images for each of said positions;

adjusting the grid relative to the compression surfaces and the breast such that the partitions thereof are focused on the focal spot when the source emits said x-rays in at least one of said positions; and

processing the information related to at least some of said projection images of the breast to generate information representative of reconstructed tomosynthesis images that differ from said projection images.

2. A method as in claim 1 in which said moving comprises moving the receptor relative to the compression surfaces and the breast and said adjusting comprises moving the grid together with the receptor.

3. A method as in claim 2 in which said moving comprises moving at least the source along an arc-shaped path relative to the compression surfaces and the breast.

4. A method as in claim 1 in which the moving comprises moving both the source and receptor relative to the compression surfaces and the breast.

5. A method as in claim 4 in which the moving comprises rotating each of the source and receptor.

6. A method as in claim 1 in which the receptor has an imaging surface from which information related to respective projection images is available, and said deriving comprises deriving reduced field of view information from an image area that is smaller than said imaging surface but encompasses at least a selected portion of the breast, and said processing comprises processing only said reduced field of view information to generate said information representative of said tomosynthesis images.

7. A method as in claim 6 including crying out an automated segmentation process to select said smaller image area as substantially coinciding with an outline of the breast on the imaging surface.

8. A method as in claim 6 in which the immobilizing includes selecting a compression paddle and including carrying out an automated process to select said smaller image area based on a characteristic of the selected compression paddle.

9. A method as in claim 6 in which said smaller image area is rectangular.

10. A system comprising:

compression surfaces defining a space in which a patient'"'"'s breast is immobilized for imaging;

a source of x-rays at one side of the compression surfaces and an x-ray imaging receptor at another side of the compression surfaces and facing the source to receive therefrom x-rays that have passed through a breast immobilized in said space, said source having a focal spot from which it selectively emits x-rays toward the receptor;

a support structure selectively moving at least one of the source and the receptor to more than two different imaging positions relative to the compression surfaces and a patient'"'"'s breast immobilized in said space;

a control selectively energizing the source to emit, at each of said positions, x-rays that pass through the breast and impinge on the receptor and selectively causing the receptor to output information related to respective two-dimensional projection x-ray images for each of said imaging positions;

an anti-scatter grid that is retractable so it can be removed from a space between one of said compression surfaces and said x-ray imaging receptor, said grid having partitions that are focused on the focal spot in the source when the grid is not retracted; and

a computer configured to process the information related to said projection images in a tomosynthesis process to generate information representative of reconstructed tomosynthesis images of the breast.

11. A system as in claim 10 in which said support structure comprises structure moving the receptor relative to the compression surfaces.

12. A system as in claim 11 in which the support structure comprises structure moving the source relative to the compression surfaces.

13. A system as in claim 10 in which the support structure comprises structure moving both the source and receptor relative to the compression surfaces.

14. A system as in claim 10 in which the support structure comprises structure rotating each of the source and receptor relative to the compression surfaces.

15. A system in claim 10 in which the receptor comprises an imaging surface from which information related to respective projection images is available, and said control causes the receptor to output reduced field of view information from an image area that is smaller than said imaging surface but encompasses at least a selected portion of a breast compressed for imaging, and said computer is configured to process only said reduced field of view information to generate said information representative of tomosynthesis images.

16. A system as in claim 15 in which said control includes a segmentation processor carrying our an automated segmentation process that selects said smaller image area as substantially coinciding with an outline of the breast on the imaging surface.

17. A system as in claim 15 in which the compression surfaces include a compression paddle selected by parameters that include size, and in which the control includes a programmed computer configured to carry out an automated process that selects said smaller image area based on a parameter related to the selected compression paddle.

18. A system as in claim 15 in which the smaller image area is rectangular.

19. A mammography method of producing reconstructed tomosynthesis images of a patient'"'"'s breast comprising:

immobilizing a patient'"'"'s breast between a source of x-rays and an x-ray imaging receptor;

moving at least one of the source and the receptor to more than two different imaging positions relative to the breast;

wherein said receptor has an overall image area selectively outputting information describing an image of a size corresponding to said overall image area;

emitting, at each of said positions, x-rays from the source that pass through the breast and impinge on the receptor while said breast remains immobilized between the source of x-rays and the imaging receptor;

deriving, from the receptor, reduced field of view information describing respective two-dimensional projection x-ray images for each of said positions, each of said projection images having an image area smaller than said overall image area of the receptor; and

processing the reduced field of view information into information describing reconstructed tomosynthesis images of the breast.

20. A method as in claim 19, including using a selectively retractable anti-scatter grid between the breast and the receptor, said grid having partitions that are focused at a focal spot in the source in at least some of said imaging positions.