Anti-inflammatory phosphonate compounds
First Claim
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1. A method for inhibiting inflammatory activity in vitro comprising contacting a sample in need of such treatment with a conjugate or a pharmaceutically acceptable salt or solvate thereof wherein the conjugate is a compound of the formula:
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[DRUG]−
(A0)nnwherein;
DRUG is a compound of formula 556;
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Abstract
The invention is related to phosphorus substituted anti-inflammatory compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.
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Citations
20 Claims
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1. A method for inhibiting inflammatory activity in vitro comprising contacting a sample in need of such treatment with a conjugate or a pharmaceutically acceptable salt or solvate thereof wherein the conjugate is a compound of the formula:
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[DRUG]−
(A0)nnwherein; DRUG is a compound of formula 556; - View Dependent Claims (3, 4, 5, 6, 7, 8, 9, 10, 11)
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2. A method of treating inflammation in a mammal, comprising administering a conjugate or a pharmaceutically acceptable salt or solvate thereof, to the mammal, wherein the conjugate is a compound of formula:
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[DRUG]−
(A0)nnwherein; DRUG is a compound of formula 556; - View Dependent Claims (12, 13, 14, 15, 16, 17, 18, 19, 20)
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Specification