Flow controlled blood pump system

• US 7,435,059 B2
• Filed: 03/03/2003
• Issued: 10/14/2008
• Est. Priority Date: 09/24/1997
• Status: Expired due to Fees

• Current Assignee: Cleveland Clinic Foundation
• Original Assignee: Cleveland Clinic Foundation
• Inventors: Smith, William A., Golding, Leonard A. R.
• Primary Examiner(s): Freay; Charles G
• Application Number:
  US10/378,444
• Publication Number:
  US 20030139643A1
• Time in Patent Office: 2,052 Days
• Field of Search: 417/26, 417/295, 417/300, 417/44.11
• US Class Current: 417/26
• CPC Class Codes: A61M 2205/3334 Measuring or controlling the flow rate
• CPC Class Codes: A61M 2205/8243 by induction
• CPC Class Codes: A61M 60/148 in line with a blood vessel using resection or like techniques, e.g. permanent endovascular heart assist devices
• CPC Class Codes: A61M 60/178 drawing blood from a ventricle and returning the blood to the arterial system via a cannula external to the ventricle, e.g. left or right ventricular assist devices
• CPC Class Codes: A61M 60/232 Centrifugal pumps
• CPC Class Codes: A61M 60/419 the force acting on the blood contacting member being permanent magnetic, e.g. from a rotating magnetic coupling between driving and driven magnets
• CPC Class Codes: A61M 60/422 the force acting on the blood contacting member being electromagnetic, e.g. using canned motor pumps
• CPC Class Codes: A61M 60/546 of blood flow, e.g. by adapting rotor speed
• CPC Class Codes: A61M 60/806 Vanes or blades
• CPC Class Codes: A61M 60/873 specially adapted for wireless or transcutaneous energy transfer [TET], e.g. inductive charging
• CPC Class Codes: A61M 60/898 the blood pump being a membrane blood pump and the membrane acting as inlet valve

Abstract

A system for pumping blood to assist or assume the cardiac function of a patient is characterized by a blood pump that exhibits a steep performance curve such that only small changes in pump flow occur for large changes in differential pressure across the pump. The pump therefore exhibits flow-limiting characteristics to protect the physiological system against harmful flow rates or pressures. Pump flow may also be limited by controlling the current provided to a driver from a power supply or by suitable restrictions within or external to the pump housing.

Claims

1. A system for pumping blood comprising:

a) a rotodynamic pump including;

i) a housing defining a chamber and an inlet and outlet in fluid communication with the chamber; and

ii) an impeller disposed within the chamber for urging fluid from the inlet toward the outlet;

iii) the pump having a performance curve at a nominal operating speed of the pump, the performance curve relating changes in the pressure differential across the pump to changes in flow through the pump;

b) a driver for imparting rotational motion to the impeller;

c) a power supply for supplying power to the driver;

d) a regulator for regulating the power supplied from the power supply to the driver;

e) flow limiting characteristics that maintain the flow through the pump within predefined limits throughout a wide range of pressure differentials across the pump, wherein the pump further comprises an axial extension connected to the housing having a conical tip and wherein the impeller comprises a plurality of blades configured to accommodate the conical tip.

2. The pumping system according to claim 1, wherein the performance curve is linear through a nominal operating set point of the pump.

3. The pumping system according to claim 1, wherein the direction of flow through the impeller blades is at an acute angle with respect to the axis of rotation of the impeller.

4. The pumping system according to claim 1, wherein the performance curve of the pump exhibits a change in flow of no more than 1 liter-per-minute for a change in pressure of 50 mm-Hg between the pump inlet and pump outlet.

5. The pumping system according to claim 1, further comprising a means to vary the pump output performance curve.

6. The pumping system defined in claim 5, wherein the impeller comprises a plurality of flat blades.

7. The pumping system according to claim 5, the means to vary pump output performance curve comprises a digital computer executing an algorithm that controls the set point according to measurement of pump input rpm, motor current, motor power, or a combination thereof.

8. The pumping system according to claim 1, wherein the flow limiting characteristics includes at least the impeller which is configured to provide a performance curve slope and a pressure differential/flow such that a flow of fluid through the pump is maintained within defined limits over a wide applied pressure differential.

9. The pumping system according to claim 8, wherein said impeller includes a plurality of main blades and a plurality of splitter blades, shorter in length than the main blades, disposed between the main blades.

10. A system for pumping blood comprising:

a) a rotodynamic pump including;

i) a housing defining a chamber and an inlet and outlet in fluid communication with the chamber; and

ii) an impeller disposed within the chamber for urging fluid from the inlet toward the outlet;

iii) the pump having a performance curve at a nominal operating speed of the pump relating changes in the pressure differential across the pump to changes in flow through the pump, wherein the performance curve of the pump exhibits a change in flow of no more than 1 liter-per-minute for a change in pressure of 50 mm-Hg between the pump inlet and pump outlet;

b) a driver for imparting rotational motion to the impeller

c) a power supply for supplying power to the driver;

d) a regulator for regulating the power supplied from the power supply to the driver;

e) flow limiting characteristics that maintain the flow through the pump within predefined limits throughout a wide range of pressure differentials across the pump;

f) means to vary the pump output performance curve, wherein the means to vary the pump output performance curve comprises a digital computer executing an algorithm that controls a set point according to measurement of pump input rpm, motor current, motor power, or a combination thereof; and

wherein the pump further comprises an axial extension connected to the housing having a conical tip and wherein the impeller comprises a plurality of blades configured to accommodate the conical tip.

11. The pumping system according to claim 10, wherein the direction of flow through the impeller blades is at an acute angle with respect to the axis of rotation of the impeller.

12. The pumping system according to claim 10, wherein each blade of the plurality of blades is generally flat and includes a curved outer edge and an angled inner edge.

13. The pumping system according to claim 10, wherein the flow limiting characteristics includes at least the impeller which is configured to provide a performance curve slope and a pressure differential/flow pump such that a flow of fluid through the pump is maintained within defined limits over a wide applied pressure differential.

14. The pumping system according to claim 13, wherein said plurality of blades of the impeller includes a plurality of main blades and a plurality of splitter blades, shorter in length than the main blades, and disposed between the main blades.