2-substituted D-homo-estra-1,3,5(10)-trienes as inhibitors of 17β-hydroxy steroid dehydrogenase type 1
First Claim
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1. A 2-substituted D-homo-estratriene compound of formula I
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Abstract
The invention relates to new 2-substituted D-homo-estra-1,3,5(10)-trienes of general formula I
in which
- R2 means a C1-C8-alkyl group, a C1-C8-alkyloxy group or a halogen atom,
- R13 means a hydrogen atom or a methyl group,
- R17 means a hydrogen atom or a fluorine atom,
as well as their pharmaceutically acceptable salts,
their manufacture and use as medicaments for prophylaxis and therapy of estrogen-dependent diseases that can be influenced by inhibition of 17β-hydroxy steroid dehydro-genase type 1.
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13 Claims
- 1. A 2-substituted D-homo-estratriene compound of formula I
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