Microfluidic devices and methods
First Claim
Patent Images
1. A dispenser assembly comprising:
- a dispenser chip including a dispenser body including one or more vertical channels; and
a sample chip having a base and a sample structure, the sample structure comprising one or more pillars and a sample surface, wherein the one or more vertical channels of the dispenser chip are cooperatively structured to receive the one or more pillars.
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Abstract
Embodiments of the invention are directed to microfluidic devices. In one embodiment, a microanalysis chip comprises a body having at least one transfer-separation channel with a channel bottom that has a bottom opening. The transfer-separation channel terminates in a discharge aperture.
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Citations
43 Claims
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1. A dispenser assembly comprising:
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a dispenser chip including a dispenser body including one or more vertical channels; and a sample chip having a base and a sample structure, the sample structure comprising one or more pillars and a sample surface, wherein the one or more vertical channels of the dispenser chip are cooperatively structured to receive the one or more pillars. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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11. A dispenser assembly comprising:
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a dispenser chip including a dispenser body including one or more vertical channels; and a sample chip having a base and a sample structure, the sample structure comprising one or more pillars and a sample surface, wherein the one or more vertical channels of the dispenser chip are cooperatively structured to receive the one or more pillars; and wherein the base and the one or more pillars are composed of the same material. - View Dependent Claims (12, 13, 14, 15, 16, 17, 18, 19, 20)
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21. A dispenser assembly comprising:
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a dispenser chip including a dispenser body including one or more vertical channels; and a sample chip having a base and a sample structure, the sample structure comprising one or more pillars and a sample surface, wherein the one or more vertical channels of the dispenser chip are cooperatively structured to receive the one or more pillars; and wherein the one or more pillars are composed of a material other than a gel.
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22. A dispenser assembly comprising:
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a dispenser chip including a dispenser body including one or more vertical channels; and a sample chip having a base and a sample structure, the sample structure comprising one or more pillars and a sample surface, wherein one or more the vertical channels of the dispenser chip are cooperatively structured to receive the one or more pillars; and further comprising one or more polypeptides either present in the one or more vertical channels or bound to the surface of the one or more pillars.
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23. A dispenser assembly comprising:
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a dispenser chip including a dispenser body including one or more vertical channels; and a sample chip having a base and a sample structure, the sample structure comprising one or more pillars and a sample surface, wherein one or more the vertical channels of the dispenser chip are cooperatively structured to receive the one or more pillars; and wherein the one or more pillars comprise biomolecules other than a polynucleotide. - View Dependent Claims (24, 25, 26, 27, 28, 29, 30, 31, 32)
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33. A dispenser assembly comprising:
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a dispenser chip including a dispenser body including one or more vertical channels; and a sample chip having a base and a sample structure, the sample structure comprising one or more pillars and a sample surface, wherein one or more the vertical channels of the dispenser chip are cooperatively structured to receive the one or more pillars; and wherein the one or more vertical channels contain a liquid other than a gel. - View Dependent Claims (34, 35, 36, 37, 38, 39, 40, 41, 42)
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43. A dispenser assembly comprising:
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a dispenser chip including a dispenser body including one or more vertical channels; and a sample chip having a base and a sample structure, the sample structure comprising one or more pillars and a sample surface, wherein the one or more vertical channels of the dispenser chip are cooperatively structured to receive the one or more pillars; wherein a fluid introduced into the one or more channels can become in contact with the pillar surface or surfaces when the dispenser chip cooperatively engages the pillars.
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Specification