Anti-human tenascin monoclonal antibody
First Claim
Patent Images
1. A monoclonal antibody to human tenascin C, said monoclonal antibody comprising SEQ ID NO:
- 1 as light chain variable region and SEQ ID NO;
2 as heavy chain variable region, or a fragment of said monoclonal antibody, wherein said antibody or fragment bind to an antigenic epitope within the EGF-like repeat of human tenascin C.
3 Assignments
0 Petitions
Accused Products
Abstract
A novel anti-human tenascin ST2146 monoclonal antibody is described endowed with high affinity with the native antigen and high tumor selectivity. The cST2146 hybridoma is stably producing the antibody in high density culture conditions and is suitable for the industrial development of ST2146-based products. ST2146 exhibits properties exploitable for both therapeutic and diagnostic applications.
-
Citations
25 Claims
-
1. A monoclonal antibody to human tenascin C, said monoclonal antibody comprising SEQ ID NO:
- 1 as light chain variable region and SEQ ID NO;
2 as heavy chain variable region, or a fragment of said monoclonal antibody, wherein said antibody or fragment bind to an antigenic epitope within the EGF-like repeat of human tenascin C. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25)
- 1 as light chain variable region and SEQ ID NO;
Specification