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Method of making modified immunodeficiency virus particles

  • US 7,439,052 B2
  • Filed: 04/10/2006
  • Issued: 10/21/2008
  • Est. Priority Date: 06/29/2000
  • Status: Expired due to Fees
First Claim
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1. A process of creating a modified, partially delipidated immunogenic immunodeficiency viral particle of an immunodeficiency virus, comprising the steps of:

  • receiving an immunodeficiency virus in a fluid,exposing the immunodeficiency virus to a delipidation process, consisting essentially of treating the immunodeficiency virus with 0.5% to 2.5% organic solvent, wherein the organic solvent is not a detergent or surfactant, wherein the delipidation process decreases the lipid content of a viral envelope of the immunodeficiency virus.

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