Biomolecular detection device
First Claim
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1. A device for biomolecular detection, comprising:
- a conducting electrode in contact with a solution containing a plurality of target molecules;
a self-assembled film with uniform pore sizes applied to at least one surface of said conducting electrode, said self-assembled film comprising a precursor sol, said precursor sol comprising an aqueous solution prepared from EO106PO70EO106, a solvent, and a compound selected from tetra-alkoxysilanes, an alkoxysilane, and a metal alkoxide, said film in contact with said solution, said film functionalized with probe molecules that chemically interacts with said target molecules.
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Abstract
A device for detecting and measuring the concentration of biomolecules in solution, utilizing a conducting electrode in contact with a solution containing target biomolecules, with a film with controllable pore size distribution characteristics applied to at least one surface of the conducting electrode. The film is functionalized with probe molecules that chemically interact with the target biomolecules at the film surface, blocking indicator molecules present in solution from diffusing from the solution to the electrode, thereby changing the electrochemical response of the electrode.
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9 Claims
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1. A device for biomolecular detection, comprising:
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a conducting electrode in contact with a solution containing a plurality of target molecules; a self-assembled film with uniform pore sizes applied to at least one surface of said conducting electrode, said self-assembled film comprising a precursor sol, said precursor sol comprising an aqueous solution prepared from EO106PO70EO106, a solvent, and a compound selected from tetra-alkoxysilanes, an alkoxysilane, and a metal alkoxide, said film in contact with said solution, said film functionalized with probe molecules that chemically interacts with said target molecules. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
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Specification