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Method for determining the glucose concentration by fluorescence polarization

  • US 7,439,080 B2
  • Filed: 03/23/2006
  • Issued: 10/21/2008
  • Est. Priority Date: 03/23/2005
  • Status: Expired due to Fees
First Claim
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1. A method for in vivo glucose monitoring in an individual, the method comprising:

  • filling a container that is permeable to glucose and having an inner space with a mixture containing a glucose-binding lectin and a probe;

    sealing the container;

    operatively coupling the container with a sensor, wherein the sensor is for measuring the fluorescence polarization;

    implanting the container and the operatively coupled sensor into the individual; and

    measuring the glucose concentration by detecting a change in viscosity in the inner space of the container by means of fluorescence polarization.

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