Method for determining the glucose concentration by fluorescence polarization
First Claim
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1. A method for in vivo glucose monitoring in an individual, the method comprising:
- filling a container that is permeable to glucose and having an inner space with a mixture containing a glucose-binding lectin and a probe;
sealing the container;
operatively coupling the container with a sensor, wherein the sensor is for measuring the fluorescence polarization;
implanting the container and the operatively coupled sensor into the individual; and
measuring the glucose concentration by detecting a change in viscosity in the inner space of the container by means of fluorescence polarization.
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Abstract
The invention generally relates to a method for in vivo glucose monitoring in which the glucose concentration is measured by means of fluorescence polarization by detecting the change in viscosity, caused by changes in the glucose concentration.
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Citations
9 Claims
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1. A method for in vivo glucose monitoring in an individual, the method comprising:
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filling a container that is permeable to glucose and having an inner space with a mixture containing a glucose-binding lectin and a probe; sealing the container; operatively coupling the container with a sensor, wherein the sensor is for measuring the fluorescence polarization; implanting the container and the operatively coupled sensor into the individual; and measuring the glucose concentration by detecting a change in viscosity in the inner space of the container by means of fluorescence polarization. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
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Specification