Aerosol inhalation system and interface accessory for use therewith

• US 7,445,006 B2
• Filed: 05/03/2005
• Issued: 11/04/2008
• Est. Priority Date: 05/03/2005
• Status: Expired due to Fees

• Current Assignee: Aeon Research And Technology, Inc.
• Original Assignee: Herbert F D'Alo, Sunil K. Dhuper
• Inventors: Dhuper, Sunil K., D'Alo, Herbert F.
• Primary Examiner(s): Yu; Justine R
• Assistant Examiner(s): DIXON, ANNETTE FREDRICKA
• Application Number:
  US11/121,688
• Publication Number:
  US 20060249158A1
• Time in Patent Office: 1,281 Days
• Field of Search: 128/200.24, 128/203.12, 128/203.25, 128/204.18, 128/205.25, 128/206.12, 128/206.21
• US Class Current: 128/203.12
• CPC Class Codes: A61M 11/06 of the injector type
• CPC Class Codes: A61M 15/0015 located upstream of the dispenser, i.e. not traversed by the product
• CPC Class Codes: A61M 15/0018 with exhalation check valves
• CPC Class Codes: A61M 15/0086 Inhalation chambers
• CPC Class Codes: A61M 15/0088 with variable volume
• CPC Class Codes: A61M 15/009 using medicine packages with incorporated spraying means, e.g. aerosol cans pocket atomiser of the injector type A61M11/08
• CPC Class Codes: A61M 16/06 Respiratory or anaesthetic masks
• CPC Class Codes: A61M 16/0816 Joints or connectors
• CPC Class Codes: A61M 16/0833 T- or Y-type connectors, e.g. Y-piece

Abstract

According to one aspect of the present invention, an accessory for an aerosol inhalation system includes a main conduit body having an outlet end for placement close to a mouth of a patient, and first and second leg conduits that are in fluid communication with the main conduit body. The accessory further includes a holding chamber having a first compartment and a second compartment separated from the first compartment, with the first compartment being sealingly and fluidly coupled to the one port associated with the first leg conduit and the second compartment being sealingly and fluidly coupled to a port associated with the second leg conduit. An arrangement of valves is provided such that when the patient exhales, the first leg conduit is sealingly closed off from the main conduit body and the second leg conduit resulting in the aerosol particles flowing into and being held in the first compartment of the holding chamber. Conversely, when the patient inhales, the first leg conduit is opened to the main conduit body and in fluid communication with the second leg conduit resulting in the aerosol particles delivered through the first port being delivered to the patient.

Claims

1. An accessory for an aerosol inhalation system comprising:

a main conduit body having an outlet end for placement close to a mouth of a patient;

a first leg conduit in fluid communication with the main conduit body an extending therefrom and including a distal end;

a second leg conduit in fluid communication with the main conduit body and extending therefrom and including a distal end, the second leg conduit being spaced apart from the first leg conduit;

a first port formed as part of the first leg conduit for attachment to a device that generates aerosol particles as a means for delivering medication to the patient;

a second port formed as part of the first leg conduit;

a third port formed as part of the second leg conduit;

a holding chamber having a first compartment and a second compartment separated from the first compartment, with the first compartment being sealingly and fluidly coupled to the second port and the second compartment being sealingly and fluidly coupled to the third port, the holding chamber being separate from the device that generates aerosol particles;

a supplemental gas port in fluid communication with the second compartment and for attachment to a supplemental gas source that delivers a prescribed amount of gas to the second compartment for storage therein and for being inhaled by the patient, the first and second compartments being connected to the first and second legs, respectively; and

an arrangement of valves such that when the patient exhales, the first leg conduit is sealingly closed off from the main conduit body and the second leg conduit resulting in the aerosol particles flowing into and being held in the first compartment of the holding chamber and when the patient exhales, the first compartment is sealed off from the main conduit and the second compartment is sealed off from the main conduit to cause the supplemental gas to be stored in the second compartment and exhaled gas is prevented from flowing into the second compartment as the patient exhales and instead the exhaled gas flows through the main conduit and the second leg conduit where it is vented therefrom and conversely, when the patient inhales, the first leg conduit is opened to the main conduit body and in fluid communication with the second leg conduit resulting in the aerosol particles delivered through the first port being delivered to the patient, the arrangement of valves including an inhalation valve located within the first leg between the main conduit body and the second port and an exhalation valve for venting exhaled gas from the patient, wherein the first compartment is located such that gas containing the aerosol particles enters the first leg, flows into the first compartment and when the inhalation valve is opened, the gas with aerosol particles flows into the main conduit body, the second compartment being located and operatively connected to the main conduit so that it receives and stores the supplemental gas that is also delivered to the patient when the patient inhales.

2. The accessory of claim 1, wherein the main conduit body, the first leg conduit and the second leg conduit are in the form of a Y-shaped connector.

3. The accessory of claim 1, wherein the first leg conduit and the second leg conduit are substantially parallel to one another and are fluidly joined at the same ends to the main conduit body.

4. The accessory of claim 1, wherein the first, second and third ports are all formed on the same face of the accessory.

5. The accessory of claim 1, wherein the second and third ports are formed the same distance from the distal ends of the first and second leg conduits, respectively.

6. The accessory of claim 1, further including cap sealingly closing off the distal end of the fast leg conduit.

7. The accessory of claim 1, wherein the exhalation valve seals off the distal end of the second leg conduit, the exhalation valve moving between an open position when the patient exhales, thereby opening the second leg conduit to atmosphere and a closed position when the patient inhales.

8. The accessory of claim 7, wherein the exhalation valve comprises a one way valve.

9. The accessory of claim 1, wherein the inhalation valve is disposed in the first leg conduit such that the first and second ports are located between the inhalation valve and the distal end thereof.

10. The accessory of claim 9, wherein the inhalation valve is formed at an interface between the main conduit body and the first leg conduit.

11. The accessory of claim 9, wherein the inhalation valve comprises a one way valve.

12. The accessory of claim 1, wherein the device comprises a nebulizer that delivers the aerosol particles at a prescribed flow rate.

13. The accessory of claim 1, wherein the holding chamber is defined by a reservoir bag with the first and second compartments defined therein and separated from one another by a bi-furcating wall, the reservoir bag being formed of a expandable/collapsible material.

14. The accessory of claim 1, wherein the first leg contains both the second port and the inhalation valve, the second leg containing both the third port and the exhalation valve.

15. An accessory for an aerosol inhalation system comprising:

a main conduit body having an outlet end for placement close to a mouth of a patient;

a first leg conduit in fluid communication with the main conduit body and including a distal end;

a second leg conduit in fluid communication with the main conduit body and including a distal end, the second leg conduit being spaced apart from the first leg conduit;

a first port formed as part of the first leg conduit for attachment to a device that generates aerosol particles as a means for delivering medication to the patient;

a second port formed as part of the first leg conduit;

a third port formed as part of the second leg conduit;

a holding chamber having a first compartment and a second compartment separated from the first compartment, with the first compartment being sealingly and fluidly coupled to the second port and the second compartment being sealingly and fluidly coupled to the third port;

a supplemental gas port in fluid communication with the second compartment and for attachment to a supplemental gas source that delivers a prescribed amount of gas to the second compartment, the first and second compartments being connected to the first and second legs, respectively; and

an arrangement of valves such that when the patient exhales, the first leg conduit is sealingly closed off from the main conduit body and the second leg conduit resulting in the aerosol particles flowing into and being held in the first compartment of the holding chamber and conversely, when the patient inhales, the first leg conduit is opened to the main conduit body and in fluid communication with the second leg conduit resulting in the aerosol particles delivered through the first port being delivered to the patient, the arrangement of valves including an inhalation valve located within the first leg between the main conduit body and the second port and an exhalation valve located in the second leg for venting exhaled gas from the patient after the exhaled gas flows though the main conduit and into the second leg, wherein the first compartment is located such that gas containing the aerosol particles enters the first leg, flows into the first holding chamber and when the inhalation valve is opened, the gas with aerosol particles flows into the main conduit body, the second compartment being located and operatively connected to the main conduit so that the second compartment receives and stores the supplemental gas that is also delivered to the patient when the patient inhales, the second compartment being in communication with the supplemental gas source and selectively in communication with the second leg so when the patient exhales, the supplemental gas continues to flow into the second compartment where the supplemental gas is stored until the patient inhales and the supplemental gas is delivered to the main conduit, wherein the holding chamber is defined by a reservoir bag with the first and second compartments defined therein and separated from one another by a bi-furcating wall, the reservoir bag being formed of a expandable/collapsible material, wherein the reservoir bag includes a fourth port integrally formed therewith and fluidly in communication with the first compartment and a fifth port integrally formed therewith and fluidly in communication with the second compartment, each of the fourth and fifth ports including fastening features that permit them to be sealingly mated with the second and third ports.

16. An accessory for an aerosol inhalation system comprising:

a main conduit body having an outlet end for placement close to a mouth of a patient;

a first leg conduit in fluid communication with the main conduit body and including a distal end;

a second leg conduit in fluid communication with the main conduit body and including a distal end, the second leg conduit being spaced apart from the first leg conduit;

a first port formed as part of the first leg conduit for attachment to a device that generates aerosol particles as a means for delivering medication to the patient;

a second port formed as part of the first leg conduit;

a third port formed as part of the second leg conduit;

a holding chamber having a first compartment and a second compartment separated from the first compartment, with the first compartment being sealingly and fluidly coupled to the second port and the second compartment being sealingly and fluidly coupled to the third port;

a supplemental gas port in fluid communication with the second compartment and for attachment to a supplemental gas source that delivers a prescribed amount of gas to the second compartment, the first and second compartments being connected to the first and second legs, respectively; and

an arrangement of valves such that when the patient exhales, the first leg conduit is sealingly closed off from the main conduit body and the second leg conduit resulting in the aerosol particles flowing into and being held in the first compartment of the holding chamber and conversely, when the patient inhales, the first leg conduit is opened to the main conduit body and in fluid communication with the second leg conduit resulting in the aerosol particles delivered through the first port being delivered to the patient, the arrangement of valves including an inhalation valve located within the first leg between the main conduit body and the second port and an exhalation valve located in the second leg for venting exhaled gas from the patient after the exhaled gas flows through the main conduit and into the second leg, wherein the first compartment is located such that gas containing the aerosol particles enters the first leg, flows into the first holding chamber and when the inhalation valve is opened, the gas with aerosol particles flows into the main conduit body, the second compartment being located and operatively connected to the main conduit so that it receives and stores the supplemental gas that is also delivered to the patient when the patient inhales, the second compartment being in communication with the supplemental gas source and selectively in communication with the second leg so when the patient exhales, the supplemental gas continues to flow into the second compartment where the supplemental gas is stored until the patient inhales and the supplemental gas is delivered to the main conduit, wherein the holding chamber is defined by a reservoir bag with the first and second compartments defined therein and separated from one another by a bi-furcating wall, the reservoir bag being formed of a expandable/collapsible material, wherein the gas stored in the first compartment is different from the gas stored in the second compartment.

17. The accessory of claim 16, further including a third valve that is associated with one of the fifth port and third port, the third valve moving between an open position when the patient inhales causing the second leg conduit and second compartment to be in fluid communication and a closed position when the patient exhales, Thereby fluidly closing off the second compartment from the second leg conduit.

18. The accessory of claim 17, wherein the third valve is a one-way valve and wherein, as the patient inhales, the supplemental gas stored in the second compartment is free to flow through the second leg conduit into the main conduit body to the patient to supplement the aerosol particles flowing through the first leg conduit.

19. The accessory of claim 17, wherein the third valve is formed in the fifth port at a location that is above an inlet of the supplemental gas into the fifth port such that the inlet is between the fifth valve and the second compartment.

20. An aerosol inhalation system comprising:

at least one device for producing aerosol particles for delivering medication to a patient through a piece of equipment in communication wit a respiratory system of the patient;

an accessory for interfacing between the at least one device and the piece of equipment, the accessory comprising;

a main conduit body having an outlet end connected to the piece of equipment;

a first leg conduit in fluid communication with the main conduit body and including a distal end;

a second leg conduit in fluid communication with the main conduit body and including a distal end, the second leg conduit being spaced apart from the first leg conduit;

a first port formed as part of the first leg conduit and connected to the at least one device;

a second port formed as part of the first leg conduit;

a third port formed as part of the second leg conduit;

a holding chamber having a first compartment that receives the medication containing aerosol particles and a second compartment separated from the first compartment, with the first compartment being sealingly and fluidly coupled only to the second port and the second compartment being sealingly and fluidly coupled only to the third port, each of the first and second compartments being formed as expandable/collapsible structures; and

an arrangement of valves including a first valve for opening up the first leg conduit to the main conduit body when the patient inhales and closing the first leg conduit to the main conduit body when the patient exhales so as to seal the first compartment from the main conduit and prevent flow of the medication stored within the first compartment to the patient, wherein a second valve is provided for venting the second leg conduit when the patient exhales; and

a supplemental gas source in communication with the second compartment and including a third valve for controlling flow of the supplemental gas into the second leg conduit from the second compartment, wherein the supplemental gas is permitted to flow into the second leg conduit from the second compartment only when the patient inhales and conversely, when the patient exhales, the second compartment is sealed from the main conduit and the second leg conduit and exhaled gas is prevented from flowing into the second compartment and instead flows within the second leg conduit to a location where it is vented therefrom, the supplemental gas flowing into and collecting within the second chamber resulting in expansion thereof when the patient exhales, wherein each of the first and second compartments holds gas that is delivered to the patient when the patient inhales due to the arrangement of the valves relative to the locations of the first and second compartments.

21. The system of claim 20, wherein the main conduit body, the first leg conduit and the second leg conduit are in the form of a Y-shaped connector.

22. The system of claim 20, wherein the first leg conduit and the second leg conduit are substantially parallel to one another and are fluidly joined at the same ends to the main conduit body.

23. The system of claim 20, wherein the first, second and third ports are all formed on the same face of the accessory.

24. The accessory of claim 20, further including cap sealingly closing off the distal end of the first leg conduit.

25. The system of claim 24, wherein the first valve comprises an inhalation valve that is disposed in the first leg conduit such that the first and second ports are located between the inhalation valve and the distal end thereof, the first valve moving between an open position when the patient inhales and a closed position when the patient exhales, the second valve comprising an exhalation valve that is disposed in and seals off the distal end of the second leg conduit, the exhalation moving between an open position when the patient exhales, thereby opening the second leg conduit to atmosphere and a closed position when the patient inhales.

26. The system of claim 25, wherein each of the first and second valves comprises a one-way valve.

27. The system of claim 20, wherein the device comprises a nebulizer that delivers the aerosol particles at a prescribed flow rate.

28. The system of claim 20, wherein the holding chamber is defined by a reservoir bag with the first and second compartments defined therein and separated from one another by a bi-furcating wall, the reservoir bag being formed of a expandable/collapsible material.

29. The system of claim 20, wherein during the first prescribed event by the patient, the supplemental gas stored in the second compartment is free to flow through the second leg conduit into the main conduit body to the patient to supplement the aerosol particles flowing through the first leg conduit.

30. The system of claim 20, wherein the third valve is a one way valve that permits the supplemental gas from flowing into the second leg conduit when the patient inhales and prevents the supplemental gas from flowing into the second leg conduit when the patient exhales gas, the exhaled gas being prevented from flowing into the first compartment by means of the first valve and into the second compartment by means of the third valve.