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Medical device having a hydration inhibitor

  • US 7,445,792 B2
  • Filed: 03/09/2004
  • Issued: 11/04/2008
  • Est. Priority Date: 03/10/2003
  • Status: Expired due to Fees
First Claim
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1. A medical device comprising:

  • an interventional component to be deployed in a patient;

    a beneficial agent to be delivered from the interventional component, the beneficial agent loaded on at least a portion of the interventional component and having a first Log P value; and

    an effective amount of a hydration inhibitor associated with the beneficial agent to control delivery of the beneficial agent from the interventional component, the hydration inhibitor having a second Log P value, the second Log P value being greater than the first Log P value, wherein the effective amount of the hydration inhibitor is an amount sufficient to shift the liquid-solid contact angle of the beneficial agent in association with the hydration inhibitor to at least 50 degrees.

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