Method and apparatus for reducing the incidence of tobacco use
First Claim
1. An apparatus for transdermally delivering nicotine-based agents to a nicotine user, comprising a microprojection member having a plurality of microprojections that are adapted to pierce said nicotine user'"'"'s stratum corneum for bolus delivery of at least one nicotine-based agent, said microprojection member including a biocompatible coating having at least one nicotine-based agent;
- wherein a total amount of the nicotine-based agent coated on the microprojections is sufficient to effectively deliver in the range of approximately 0.02-2.0 mg of the agent to the nicotine user, and wherein the composition of the coating is selected to deliver at least 50% of the total amount of the nicotine-based agent coated on the microprojection into the skin of the user one hour or less following application of the microprojection member to the user'"'"'s skin.
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Abstract
An apparatus for transdermally delivering a nicotine-based agent to a tobacco or nicotine user comprising a microprojection member having a plurality of microprojections that are adapted to pierce the stratum corneum of the tobacco user, the microprojection member having a biocompatible coating disposed thereon that includes a nicotine-based agent.
45 Citations
18 Claims
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1. An apparatus for transdermally delivering nicotine-based agents to a nicotine user, comprising a microprojection member having a plurality of microprojections that are adapted to pierce said nicotine user'"'"'s stratum corneum for bolus delivery of at least one nicotine-based agent, said microprojection member including a biocompatible coating having at least one nicotine-based agent;
- wherein a total amount of the nicotine-based agent coated on the microprojections is sufficient to effectively deliver in the range of approximately 0.02-2.0 mg of the agent to the nicotine user, and wherein the composition of the coating is selected to deliver at least 50% of the total amount of the nicotine-based agent coated on the microprojection into the skin of the user one hour or less following application of the microprojection member to the user'"'"'s skin.
- View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
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15. A method for transdermally delivering a nicotine-based agent to a nicotine user, comprising the steps of:
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providing a microprojection member having a plurality of microprojections that are adapted to pierce said nicotine user'"'"'s stratum corneum for bolus delivery of at least one nicotine-based agent, said microprojections including a biocompatible coating having at least one nicotine-based agent;
wherein a total amount of the nicotine-based agent coated on the microprojections is sufficient to effectively deliver in the range of approximately 0.02-2.0 mg of the agent to the nicotine user; andapplying said microprojection member to said nicotine user'"'"'s skin, whereby said microprojection members pierce said stratum corneum and deliver said nicotine-based agent, and wherein the composition of the coating is selected to deliver at least 50% of the total amount of the nicotine-based agent coated on the microprojection into the skin of the user one hour or less following application of the microprojection member to the user'"'"'s skin. - View Dependent Claims (16, 17, 18)
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Specification