Analytical instruments, biosensors and methods thereof
First Claim
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1. A method for removing interfering agents from a composite membrane comprising:
- providing an electrochemical sensor comprising an electrode, said electrode including a composite membrane disposed thereon, said composite membrane comprising two or more layers;
providing an electrical source in electrical contact with said electrode;
exposing the electrode to a first sample;
measuring a signal generated by the first sample by use of the electrical source;
replacing the first sample with a rinse solution after said measuring; and
applying an electrical potential with the electrical source to said electrode while exposing the electrode to said rinse solution, wherein the electrical potential is sufficient to cause at least a portion of the interfering agents in said composite membrane to be oxidized and removed.
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Abstract
An electrochemical sensor system and membrane and method thereof for increased accuracy and effective life of electrochemical and enzyme sensors.
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Citations
14 Claims
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1. A method for removing interfering agents from a composite membrane comprising:
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providing an electrochemical sensor comprising an electrode, said electrode including a composite membrane disposed thereon, said composite membrane comprising two or more layers; providing an electrical source in electrical contact with said electrode; exposing the electrode to a first sample; measuring a signal generated by the first sample by use of the electrical source; replacing the first sample with a rinse solution after said measuring; and applying an electrical potential with the electrical source to said electrode while exposing the electrode to said rinse solution, wherein the electrical potential is sufficient to cause at least a portion of the interfering agents in said composite membrane to be oxidized and removed. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13)
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14. A method for removing interfering agents from a composite membrane comprising:
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providing an electrochemical sensor comprising an electrode, said electrode including a composite membrane disposed thereon, said composite membrane comprising at least one polymeric layer; providing an electrical source in electrical contact with said electrode; applying an electrical potential with the electrical source to said electrode sufficient to cause at least a portion of the interfering agents in said composite membrane to be oxidized and removed; and measuring a signal generated by the electrode by use of the electrical source, wherein the electrical source is in electrical communication with the electrode during the measuring of the signal and the removal of interfering agents from the composite membrane, and wherein said electrical potential comprises a range of about 0.1 to 0.8 V versus an on-board Ag/AgNO3 reference electrode.
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Specification