Methods and devices for registering optical measurement datasets of an optical system

• US 7,458,683 B2
• Filed: 06/16/2003
• Issued: 12/02/2008
• Est. Priority Date: 06/16/2003
• Status: Expired due to Term

• Current Assignee: Amo Manufacturing Usa, Llc (Johnson & Johnson)
• Original Assignee: Amo Manufacturing Usa, Llc (Johnson & Johnson)
• Inventors: Chernyak, Dimitri
• Primary Examiner(s): Dang; Hung X.
• Assistant Examiner(s): Tra; Tuyen Q
• Application Number:
  US10/463,674
• Publication Number:
  US 20040263785A1
• Time in Patent Office: 1,996 Days
• Field of Search: 351/200, 351/205, 351/211, 351/212, 351/221, 351/246, 351/206, 382/128, 382293-298, 382/218, 382/219, 382/100, 382/115, 382/117, 600/398, 600/399, 604/289, 606 4- 6, 607/53, 607/54, 128/922, 345467-4723
• US Class Current: 351/205
• CPC Class Codes: A61B 3/0025 characterised by electronic signal processing, e.g. eye models
• CPC Class Codes: A61B 3/1015 for wavefront analysis

Abstract

The present invention provides methods, systems and software for registering a first dataset of an object with a second dataset of an object. In one embodiment, the present invention measures refractive errors of an optical system. The method comprises obtaining a first and second optical measurement of the optical system. The first and second optical measurements are registered with each other and may improve the diagnosis and/or treatment of the refractive errors of the optical system. In one embodiment the first optical measurement is a topographical map and the second optical measurement is a wavefront measurement.

Claims

1. A method of registering datasets of an eye obtained by two different instruments, the method comprising:

obtaining a first high-order optical tissue surface shape dataset from an eye with a first instrument while the eye is aligned with the first instrument;

obtaining a first image of the eye associated with the first dataset while the eye is aligned with the first instrument and while obtaining the first dataset;

obtaining a second high-order optical tissue surface shape dataset from the eye with a second instrument while the eye is aligned with the second instrument while the eye is not aligned with the first instrument, the second instrument being separate from the first instrument;

obtaining a second image of the eye associated with the second dataset while the eye is aligned with the second instrument and while obtaining the second dataset;

locating a plurality of distinctive data points of the eye in each of the datasets, the distinctive data points for each dataset identified from the associated image by comparing calculating values from across the image; and

using the distinctive data points to torsionally register the first dataset with the second dataset.

2. The method of claim 1 wherein the dataset from the first instrument comprises a time series of wavefront measurements of the eye.

3. The method of claim 2 wherein the distinctive data points comprise one or more landmarks in the eye.

4. The method of claim 3 wherein the landmarks comprise at least one of a limbus, iris, iris center, iris pattern, pupil, pupil center, pupil boundary, or corneal vertex.

5. The method of claim 3 wherein the distinctive data points comprise an iris center, wherein using the distinctive data points to register comprises matching the iris centers of the first data set and the second data set,

the method further comprising scaling at least one of the dataset so that sizes of the first dataset and second data set substantially match each other.

6. The method of claim 2 further comprising generating an ablation pattern for the eye based on an analysis of the first dataset and second dataset.

7. The method of claim 1 further comprising overlaying the first data set and the second data set.

8. The method of claim 7 comprising measuring a cyclotorsional offset between the first dataset and second dataset and compensating for the cyclotorsional offset prior to overlaying the first data set and the second data set.

9. The method of claim 1 wherein using the distinctive data points comprises calculating relative positional and torsional offsets between the first data set and the second data set.

10. The method of claim 9 wherein calculating relative positional and torsional offsets comprises establishing a coordinate system transformation between the first data set and second data set.

11. The method of claim 1 wherein the first and second instruments comprise different types of instruments, and further comprising deriving a refractive treatment from the registered first and second datasets.

12. A method of registering datasets of an eye obtained by two different instruments, the method comprising:

obtaining a first high-order corneal aberration dataset from an eye with a first instrument, wherein the dataset from the first instrument comprises a wavefront measurement of the eye;

obtaining a second high order corneal surface shape dataset from the eye with a second instrument, wherein the second dataset from the second instrument comprises a corneal topographic map of the eye;

locating distinctive data points of the eye in each of the datasets by identifying a plurality of sectors of an iris of the eye, the distinctive data points comprising iris pattern landmarks with one located iris pattern landmark being disposed in each of the sectors, and an iris or pupil center landmark;

using the distinctive data points to register the first dataset with the second dataset by calculating relative positional offsets between the first data set and the second data set with the iris or pupil center landmarks, and by calculating relative torsional offsets between the first dataset and second dataset with the iris pattern landmarks; and

scaling at least one of the datasets so that sizes of the first dataset and second dataset substantially match each other.

13. A method of improving a measurement of refractive errors of an optical system, the method comprising:

obtaining a first high order optical measurement of a surface of the optical system with a first instrument;

after the first optical measurement has been obtained, obtaining a second high order measurement of a surface of the optical system with a second instrument; and

torsionally registering the first optical measurement of the optical system with the second measurement of the optical system in response to calculated imaging landmarks.

14. The method of claim 13 wherein the optical system comprises optical tissues of an eye, wherein the first or second measurement of the optical system comprises a time series of wavefront measurements of the eye and the other measurement comprises a corneal topographical map of the eye.

15. The method of claim 14 further comprising diagnosing the optical errors of the eye using the registered corneal topographical map and the wavefront measurement of the eye.

16. The method of claim 15 further comprising deriving a refractive treatment from the registered first and second measurements.

17. The method of claim 14 comprising generating an ablation pattern for the eye by analyzing at least one of the corneal ablation map and the wavefront measurement.

18. The method of claim 14 wherein registering the corneal topographical map of the eye with the wavefront measurement of the eye comprises:

locating landmarks in the corneal topographical map of the eye and the wavefront measurement of the eye;

calculating at least one of a relative positional and torsional offsets between the landmarks to generate a coordinate system transformation between the topographical map and wavefront measurement; and

using the coordinate system transformation to align the corneal topographical map of the eye with the wavefront measurement of the eye.

19. The method of claim 18 wherein the landmarks comprise at least one of a limbus, iris, iris center, iris pattern, pupil, pupil center, pupil boundary, or corneal vortex.

20. The method of claim 14 wherein registering comprises scaling a size of at least one of the corneal topographical map and the wavefront measurement.

21. The method of claim 14 wherein registering comprises overlaying the corneal topographical map of the eye with the wavefront measurement of the eye.

22. A system for registering a first high order optical surface dataset with a second high order optical surface dataset, each of the datasets including high order optical surface information with associated image information, the image information of the first dataset being different than the image information of the second dataset, the system comprising:

a processor;

a memory coupled to the processor, the memory comprising a plurality of modules of computer-implemented instructions embodied on a tangible computer medium for registering the first dataset with the second dataset, the modules comprising;

a module for receiving the first dataset of an eye, the high order optical surface information of the first dataset comprising a time series of wavefront data;

a module for receiving the second dataset of the eye;

a module for calculating distinctive imaging data points from the image information in each of the datasets of the eye; and

a module for using the distinctive data points to torsionally register the first dataset with the second dataset.

23. The system of claim 22 wherein the second dataset comprises a corneal topographical map.

24. The system of claim 22 Wherein the system further comprises a corneal topographer that obtains the second dataset.

25. The system of claim 22 wherein the system further comprises a wavefront measurement device that obtains the first dataset.

26. The system of claim 22 wherein the modules further comprise a module for calculating an ablation pattern based on the first dataset and the second dataset.

27. The system of claim 26 further comprising a laser assembly for delivering the ablation pattern.

28. The system of claim 22 wherein the module for using the distinctive data points to register the first dataset with the second dataset is configured to scale a size of at least one of the first dataset and second dataset to substantially match the datasets with each other.

29. The system of claim 22 wherein the distinctive data points comprise landmarks in the eye.

30. The system of claim 29 wherein the module for locating distinctive data points is configured to locate at least one of a pupil, pupil center, pupil boundary, iris center, iris pattern, iris boundary, limbus, and corneal vertex in the first and second datasets.

31. The system of claim 30 wherein the module for using the distinctive data points is configured to calculate and compensate for a positional and torsional offset between the distinctive data points in the first dataset and second dataset.

32. The system of claim 31 wherein the module for using the distinctive data points is configured to overlay the first dataset with the second dataset.

33. A system for registering a first high-order optical surface measurement of an optical system with a second high-order optical surface measurement of the optical system, the system comprising:

a processor;

a memory coupled to the processor, the memory comprising a plurality of modules with processor-implementable instructions embodied on a tangible medium for registering the first optical measurement with the second optical measurement, the modules comprising;

a module for obtaining the first optical measurement of the optical system and first image information obtained simultaneously with the first optical measurement of the optical system;

a module for obtaining the second optical measurement of the optical system and second image information obtained simultaneously with the second optical measurement of the optical system, the second image information obtained at a different time than the first image information; and

a module for torsionally registering the first optical measurement of the optical system with the second optical measurement of the optical system in response to imaging landmarks from the first and second image information.

34. The system of claim 33 further comprising a module for diagnosing the optical errors of the optical system using the first optical measurement and the second optical measurement of the optical system.

35. The system of claim 34 further comprising a module for generating an ablation pattern to correct the diagnosed optical errors of the optical system.

36. A system for measuring optical errors of an optical system of an eye, the system comprising:

means for obtaining a first high-order optical surface measurement of the optical system while the eye is at a first location;

means for obtaining a second high-order optical surface measurement of the optical system while the eye is at a second location; and

means for torsionally registering, in response to calculated imaging landmarks, the first optical measurement of the optical system with the second optical measurement of the optical system.

37. The system of claim 36 further comprising means for diagnosing the optical errors of the optical system using the first optical measurement and the second optical measurement of the optical system.

38. The system of claim 37 further comprising means for correcting the diagnosed optical errors of the optical system.

39. A computer program of code modules stored on a computer-readable storage medium for measuring optical errors of an optical system, the computer program comprising:

a code module for receiving a first high-order optical surface dataset of the optical system;

a code module for receiving a second high-order optical surface dataset of the optical system;

a code module for locating distinctive calculated data points in each of the datasets of the optical system; and

a code module for using the distinctive data points to torsionally register the first dataset with the second dataset when a location of the optical systems is different for the second dataset and the first dataset.

40. The computer program of claim 39 wherein the first dataset comprises a wavefront measurement.

41. The computer program of claim 39 or 40 wherein the second dataset is a topographical map.

42. The computer program of claim 39 further comprising a code module for diagnosing the optical errors of the optical system.

43. The computer program of claim 42 comprising a code module for generating an ablation pattern to correct the optical errors, wherein the ablation pattern is at least in part based on the diagnosis of the optical errors of the optical system.

44. A computer program of code modules stored on a computer-readable storage medium for registering a first high-order optical measurement of an optical system of an eye with a second high-order optical measurement of the optical system, the computer program comprising:

a code module for obtaining the first optical surface measurement of the optical system;

a code module for obtaining the second optical surface measurement of the optical system; and

a code module for identifying, from calculated imaging values, distinctive data points in each optical surface measurement; and

a code module for torsionally registering the first optical measurement of the optical system with the second optical measurement of the optical system in response to the distinctive data points when a location of the eye is different fro the second measurement and the fist measurement.

45. The computer program of claim 44 further comprising a code module for diagnosing the optical errors of the optical system using the first optical measurement and the second optical measurement of the optical system.

46. The computer program of claim 45 further comprising a code module for generating an ablation pattern to correct the diagnosed optical errors of the optical system.

47. A method of registering a corneal topographic map of an eye that is obtained by a first instrument with a wavefront measurement of the eye that is obtained by a second instrument, the method comprising:

locating, from calculated image values, a plurality of imaging landmarks in a first image of the eye associated with the corneal topographical map;

locating a plurality of corresponding imaging landmark in a second image of the eye associated with the wavefront measurement, the second image of the eye being different than the first image of the eye;

determining a relative positional and torsional offset between the landmarks; and

registering the corneal topographical map with the wavefront measurement.

48. The method of claim 47 wherein the landmarks comprise at least one of a limbus, iris, iris center, iris pattern, pupil, pupil center, pupil boundary, and corneal vertex.

49. The method of claim 47 further comprising overlaying the corneal topographical map with the wavefront measurement.