Apparatus and method for measuring hemodynamic parameters

• US 7,468,037 B2
• Filed: 02/16/2005
• Issued: 12/23/2008
• Est. Priority Date: 02/18/2004
• Status: Expired due to Fees

• Current Assignee: Jozsef Beres, Miklos Illyes
• Original Assignee: Jozsef Beres, Miklos Illyes
• Inventors: Beres, Jozsef, Illyes, Miklos
• Primary Examiner(s): Marmor, II; Charles A
• Assistant Examiner(s): SAIDI, AZADEH
• Application Number:
  US10/596,240
• Publication Number:
  US 20070106162A1
• Time in Patent Office: 1,406 Days
• Field of Search: 600/490, 600/300, 600/494, 600/495, 600/504
• US Class Current: 600/490
• CPC Class Codes: A61B 5/02007 Evaluating blood vessel condition, e.g. elasticity, compliance
• CPC Class Codes: A61B 5/02028 Determining haemodynamic parameters not otherwise provided for, e.g. cardiac contractility or left ventricular ejection fraction
• CPC Class Codes: A61B 5/022 by applying pressure to close blood vessels, e.g. against the skin; Ophthalmodynamometers
• CPC Class Codes: A61B 5/02225 using the oscillometric method
• CPC Class Codes: A61B 5/0285 Measuring or recording phase velocity of blood waves

Abstract

An apparatus for measuring hydrodynamic parameters, especially for Augmentation Index (Aix) and/or Ejection Duration (ED), by non-invasive, cuff based occlusive, blood pressure measurement, which apparatus comprises occlusive, oscillometric automatic blood pressure meter and units. There can also be a method for non-invasive measurement of hemodynamic characteristics, especially AN and/or ED with an occlusive, pressure sensor cuff, placed on the brachial artery, wherein the apparatus according to the invention samples and analyzes and evaluates the signal flow of the oscillations of pulse waves using an unusual stepwise blood pressure measurement.

Claims

1. Apparatus An apparatus for measuring hemodynamic parameters, by non-invasive, cuff based occlusive, blood pressure measurement, which apparatus comprises occlusive, oscillometric automatic blood pressure meter and units, determining the values of hemodynamic parameters, comprising

an oscillation wave separating and storing signal detector for detecting an oscillation signal, the sampling rate thereof is at least 200/heart cycle;

and said signal detector has a storage unit resolution that is organized at least 9 bit,

a digital anti-filter connected to the signal detector to compensate the distortions rising at sampling, separating and digitizing the oscillation wave, detected by the signal detector,

an amplitude arithmetic unit connected to the anti-filter establishing an Augmentation Index (Aix); and

a synthesizing unit connected to the anti-filter establishing an Ejection Duration (ED).

2. The apparatus according to claim 1, wherein the sampling rate of the signal detector is 180-220/second.

3. The apparatus according to claim 1, wherein the storage unit storing the signals, generated by the oscillation wave, is organized 10-12 bit.

4. The apparatus according to claim 1 further comprising a time-arithmetic unit establishing a Pulse Wave Velocity (PWV), or integrator unit establishing a Systole Area Index (SAI) and Diastole Area Index (DAI).

5. The apparatus according to claim 1, wherein the amplitude arithmetic unit, the synthesizing unit, a time-arithmetic unit, or an integrator unit are joined to a common program controller, and compiled to an analyzer.

6. The apparatus according to claim 1, further comprising a portable, 24 h ambulatory blood pressure monitor.

7. The apparatus according to claim 1, further comprising a telemedical home care system.

8. The apparatus according to claim 1, further comprising a 24 h blood pressure monitor, which is controlled by a built-in ECG.

9. A method for non-invasive measurement of hemodynamic characteristics comprising the steps of:

(a) performing a standard stepwise blood pressure measurement using an occlusive, pressure-sensor cuff placed on the brachial artery;

(b) storing systolic blood pressure (SBP), diastolic blood pressure (DBP), and heart rate (HR) values;

(c) subsequently setting the cuff to supra-systolic pressure range over the systolic pressure;

(d) performing a pressure oscillometric pulse wave detection at supra-systolic pressure range, receiving oscillation curve and simultaneously by an “

anti-filter”

process compensating for signal distortions appearing at sampling;

(e) calculating an Augmentation Index (Aix) on the basis of the wave amplitudes from the oscillation curves so received; and

(f) calculating the Ejection Duration (ED) value on the oscillating curve determining the minimum point after the first reflex wave.

10. The method according to claim 9, wherein the sampling rate of the pressure oscillometric rules wave detection is taken at least 180 samples per second, and the digitized signals of the oscillation curve are stored at least in 9 bit resolution.

11. The method according to claim 9, wherein the cuff is set to +35 mmHG pressure, over the systolic pressure, a pulse wave velocity (PMV) value is calculated from a time shift of the main wave and the first reflex, respectively of a measured sternal notch and pubic bone distance of a patient, or the cuff is set at or near to a previously determined diastolic value, and the received heart cycle curve is divided into two parts with the ED end-point, to constitute Systole Area Index (SAI) and Diastole Area Index (DAI) values.