Cartridge for use with electrochemical sensor
First Claim
Patent Images
1. A cartridge, comprising:
- a storage component including reservoirs that each contains a solution, the storage component including a cover and a base,the cover having pockets extending from a side of a common platform, each pocket defining a portion of one of the reservoirs,the base having openings extending through the base such that the openings are each aligned with a different one of the pockets;
a transport component separate from the storage component and configured to be coupled with the storage component,the transport component being configured to transport the solutions from the reservoirs to a sensor held by the transport component, the sensor being configured to detect a presence and/or amount of an agent in a liquid sample,the transport component includes disruption mechanisms configured to be received in the openings upon coupling of the storage component and the transport component.
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Abstract
A cartridge is disclosed. The cartridge includes an independent storage component and transport component. The storage component can be coupled with the transport component. The storage component includes one or more pockets that each contain a solution to be used in an assay. The transport component is configured to transport the solutions from the pockets of the storage component to a sensor positioned in the transport component.
38 Citations
61 Claims
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1. A cartridge, comprising:
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a storage component including reservoirs that each contains a solution, the storage component including a cover and a base, the cover having pockets extending from a side of a common platform, each pocket defining a portion of one of the reservoirs, the base having openings extending through the base such that the openings are each aligned with a different one of the pockets; a transport component separate from the storage component and configured to be coupled with the storage component, the transport component being configured to transport the solutions from the reservoirs to a sensor held by the transport component, the sensor being configured to detect a presence and/or amount of an agent in a liquid sample, the transport component includes disruption mechanisms configured to be received in the openings upon coupling of the storage component and the transport component. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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12. A cartridge, comprising:
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a storage component including reservoirs that each contains a solution, the storage component including pockets extending from a side of a common platform, each pocket defining a portion of one of the reservoirs; and a transport component separate from the storage component and configured to be coupled with the storage component, the transport component being configured to transport the solutions from the reservoirs to a sensor held by the transport component, the sensor being configured to detect a presence and/or amount of an agent in a liquid sample, and the transport component including a valve configured to control the flow of a solution around an obstruction positioned between an input channel in the transport component and an output channel in the transport component, the valve including a flexible material positioned over the obstruction and a portion of the input channel and a portion of the output channel. - View Dependent Claims (13, 14, 15, 16, 17, 18, 19)
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20. A transport component for use with a cartridge, comprising:
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a transport component configured to be coupled with a storage component that is separate from the transport component, the storage component having reservoirs that each hold a solution; the transport component being configured to transport the solutions from the reservoirs to a sensor held by the transport component, the transport component including a valve configured to control the flow of a solution from an input channel in the transport component to an output channel in the transport component, the valve includes a flexible material defining a portion of the input channel; and the sensor being configured to detect the a presence and/or amount of an agent in a liquid sample. - View Dependent Claims (21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34)
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35. A method, comprising:
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coupling a storage component with a transport component so as to form a cartridge, the storage component including one or more reservoirs that each contain a solution, the storage component including a cover and a base, the cover having pockets extending from a side of a common platform, each pocket defining a portion of one of the reservoirs, the base having openings extending through the base such that the openings are each aligned with a different one of the pockets; and the transport component configured to transport the solutions from one or more of the reservoirs to a sensor held by the transport component, the sensor being configured to detect the a presence and/or amount of an agent in a liquid sample the transport component including disruption mechanisms that are received in the openings upon coupling of the storage component and the transport component. - View Dependent Claims (36, 37, 38)
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39. A cartridge comprising:
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a storage component including reservoirs that each contains a solution, the storage component including pockets extending from a side of a common platform, each pocket defining a portion of one of the reservoirs; and a transport component separate from the storage component and configured to be coupled with the storage component, the transport component being configured to transport the solutions from the reservoirs to a sensor held by the transport component, the sensor being configured to detect a presence and/or amount of an agent in a liquid sample, and the transport component including a vent channel, an input channel and an output channel meeting at a valve, the valve being configured to control flow of a solution from the input channel to the output channel while venting gasses into the vent channel. - View Dependent Claims (40, 41, 42, 43, 44, 45, 46, 47, 48, 49)
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50. A cartridge, comprising:
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a storage component including reservoirs that each contains a solution, the storage component including pockets extending from a side of a common platform, each pocket defining a portion of one of the reservoirs; and a transport component separate from the storage component and configured to be coupled with the storage component, the transport component being configured to transport the solutions from the reservoirs to a sensor held by the transport component, the sensor being configured to detect a presence and/or amount of an agent in a liquid sample, and the transport component including a valve configured to control flow of a solution around an obstruction positioned between an input channel and an output channel, the valve including a flexible material positioned over the obstruction such that a displacement between the obstruction and the flexible material changes during operation of the valve, a portion of the input channel sloping toward the flexible material when moving along the input channel toward the valve. - View Dependent Claims (51, 52, 53, 54, 55, 56, 57, 58)
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59. A cartridge, comprising:
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a storage component including reservoirs that each contains a solution, the storage component including pockets extending from a side of a common platform, each pocket defining a portion of one of the reservoirs; and a transport component separate from the storage component and configured to be coupled with the storage component, the transport component being configured to transport the solutions from the reservoirs to a sensor held by the transport component, the sensor being configured to detect a presence and/or amount of an agent in a liquid sample, and the transport component includes disruption mechanisms configured to disrupt the sealing integrity of a material on the storage component upon coupling of the transport component and the storage component, the sealing integrity being disrupted so as to provide an outlet through which a solution in a reservoir can flow out of the storage component, one or more of the disruption mechanisms include a cup. - View Dependent Claims (60)
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61. A cartridge, comprising:
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a storage component including reservoirs that each contains a solution, the storage component including pockets extending from a side of a common platform, each pocket defining a portion of one of the reservoirs; and a transport component separate from the storage component and configured to be coupled with the storage component, the transport component being configured to transport the solutions from the reservoirs to a sensor held by the transport component, the sensor being configured to detect a presence and/or amount of an agent in a liquid sample, the transport component including disruption mechanisms configured to disrupt the sealing integrity of a material on the storage component upon coupling of the transport component and the storage component, the sealing integrity being disrupted so as to provide an outlet through which a solution in a reservoir can flow out of the storage component, and one or more of the disruption mechanisms being configured to stretch the material upon coupling of the storage component and the transport component.
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Specification