Method for detecting vibrations in a biological organism using real-time vibration imaging

• US 7,477,571 B2
• Filed: 02/07/2006
• Issued: 01/13/2009
• Est. Priority Date: 04/03/2003
• Status: Expired due to Fees

• Current Assignee: SRI International, Inc.
• Original Assignee: SRI International, Inc.
• Inventors: Donaldson, Katherine, Melese, Philip, Dubois, Lawrence H., Lavelle, Eric
• Primary Examiner(s): Lobo, Ian J
• Application Number:
  US11/351,316
• Publication Number:
  US 20060209631A1
• Time in Patent Office: 1,071 Days
• Field of Search: 367/149, 736/53, 736/55, 736/56
• US Class Current: 367/7
• CPC Class Codes: A61B 5/11 Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb for measuring pulse A61B5/02 ;A61B5/1038 takes precedence; motion detection to correct for motion artifacts in physiological signals A61B5/721
• CPC Class Codes: A61B 5/7257 using Fourier transforms
• CPC Class Codes: G01H 9/002 for representing acoustic field distribution sonar systems for imaging G01S7/56, G01S15/89; acoustic holography G03H3/00

Abstract

The present invention provides a method for detecting vibration information by receiving electromagnetic radiation reflected or emitted from a biological organism at a light amplitude modulation detector array to provide real-time imaging of the target object. The detected radiation may be visible light, infrared or ultraviolet radiation, and/or of other desired frequency ranges. The detected radiation is preferably AC-coupled to isolate components relating to oscillations of the biological organism from components relating to ambient radiation, e.g. background sunlight. The isolated oscillations may then be digitized, stored, and subjected to processing such as a Fourier transform to generate outputs representative of frequencies of oscillation. This output can then be used for analysis of the target object.

Claims

1. A method for detecting vibrations in a biological organism, comprising:

a) receiving a light signal from each of a plurality of regions of said biological organism at a corresponding plurality of light amplitude modulation detectors, wherein said light amplitude modulation detectors detect changes in the light amplitude of said light signal;

b) generating from each of said received light signals a signal that is correlated to a vibration of the corresponding region;

c) digitizing each of said correlated signals; and

d) generating from said digitized signals an output representing said vibrations of said regions of said biological organism.

2. The method as set forth in claim 1, further comprising processing said digitized signals.

3. The method as set forth in claim 2, wherein said processing comprises executing a Fourier transform on said digitized signals, executing wavelet analysis of said digitized signals, or filtering said digitized signals.

4. The method as set forth in claim 3, wherein said filtering comprises match filtering.

5. The method as set forth in claim 1, further comprising optically filtering said received signals.

6. The method as set forth in claim 1, further comprising displaying a representation of said biological organism visually correlated with said generated signals representing said vibrations of said corresponding regions.

7. The method as set forth in claim 1, wherein said generating comprises generating a temporal spectral signal corresponding to the vibration of each corresponding region.

8. The method as set forth in claim 1, wherein said vibrations in said biological organism are generated from movement of biological fluids, air, organs, tissues, muscles, or body parts.

9. The method as set forth in claim 1, further comprising utilizing said output to detect or measure a property of said biological organism.

10. The method as set forth in claim 9, wherein said property is selected from the group consisting of heart rate, pulse rate, tremor, eye-blink rate, blood oxygen level, eye movement and blood flow.

11. The method as set forth in claim 1, wherein said biological organism is a mammal.

12. The method as set forth in claim 1, wherein said light signals comprise modulated light reflected from said biological organism.

13. The method as set forth in claim 12, said reflected light comprises light having a frequency in at least one of the visible light frequency range, the infrared frequency range, and the ultraviolet radiation range.

14. The method as set forth in claim 1, wherein said light signals comprise modulated light emitted from said biological organism.

15. The method as set forth in claim 14, wherein said emitted light comprises thermal infrared radiation or fluorescent radiation.

16. The method as set forth in claim 1, further comprising extracting from said received signals a representation of an oscillation of the corresponding regions.

17. The method as set forth in claim 16, wherein said extracting comprises removing from said received signals at least one component representing ambient radiation in a vicinity of said biological organism.

18. The method as set forth in claim 16, wherein said extracting comprises AC-coupling, high-pass temporal filtering, or DC-rejection of said received signals.