Automatic conveyor driven by hydrogels, provided with an adjustable output characteristic for conveying a medium

• US 7,479,135 B2
• Filed: 07/12/2005
• Issued: 01/20/2009
• Est. Priority Date: 01/13/2003
• Status: Expired due to Fees

• Current Assignee: Disetronic Licensing Ag
• Original Assignee: Disetronic Licensing Ag
• Inventors: Arndt, Karl-Friedrich, Klenke, Christian, Richter, Andreas, Schiltges, Gilbert
• Primary Examiner(s): Sirmons; Kevin C
• Assistant Examiner(s): Hall; Deanna K
• Application Number:
  US11/180,315
• Publication Number:
  US 20060116664A1
• Time in Patent Office: 1,288 Days
• Field of Search: 604/892.1
• US Class Current: 604/892.1
• CPC Class Codes: A61M 2005/14513 with secondary fluid driving or regulating the infusion
• CPC Class Codes: A61M 5/14244 adapted to be carried by the patient, e.g. portable on the body
• CPC Class Codes: A61M 5/14526 the piston being actuated by fluid pressure

Abstract

A device for the dosed output of a substance, the device involving hydrogel-based osmotic drive, wherein output characteristics of the device, including a time profile, may be adjusted by a user. In some embodiments, the device may be used once and, in other embodiments, it may be used several times.

Claims

1. An automatic conveyor for conveying a medium, the conveyor having an adjustable output characteristic, wherein by operation of a suitable swelling agent an actuator based on at least one swellable polymer network is activated and triggers an automatic chain of action comprising at least one of (a) a delay time from the user initiating the conveyor to the start of the conveying, (b) a period of time within which the medium is actually conveyed, (c) a characteristic curve during conveying, (d) a volume of medium to be conveyed per unit of time, and (e) a total volume of medium to be conveyed, wherein at least one of the delay time, the period of time, the characteristic curve, the volume and the total volume can be adjusted by the user, and wherein the characteristic curve during conveying is adjustable by selectively arranging one or more of a number of serially arranged selector elements, each of said elements having at least one function bore.

2. The automatic conveyor according to claim 1, wherein said selector elements comprise selector disks.

3. The automatic conveyor according to claim 1, wherein said selector elements each have concentrically arranged function bores.

4. The automatic conveyor according to claim 3, wherein said selective arranging comprises selectively aligning said bores relative to each other.

5. The automatic conveyor according to claim 1, wherein said conveying is pulsatile conveying.

6. The automatic conveyor as claimed in claim 1, wherein the actuator comprises actuator segments, and wherein the serially arranged selector elements interconnect actuator segments having one of different material basis, microscopic/macroscopic structure and filling quantity.

7. The automatic conveyor as claimed in claim 1, wherein the serially arranged selector elements contain segments with materials couplable into an actuator force flow, said materials not actuator active and serving the purpose of interrupting conveying and simply forwarding the actuator forces and the swelling agent.

8. The automatic conveyor as claimed in claim 1, wherein the serially arranged selector elements contain segments of different swelling agent delivery line cross sections with defined swelling agent throughput amounts per unit of time.

9. The automatic conveyor as claimed in claim 1, wherein the serially arranged selector elements contain segments made of materials with chronologically defined dissolution properties in the actuator swelling agent.

10. The automatic conveyor as claimed in claim 1, wherein the serially arranged selector elements contain segments of different cross sections which enable hydraulically active stepping-up and stepping-down mechanisms.

11. The automatic conveyor according to claim 1, wherein the characteristic curve is based on one of continuous or pulsatile conveying.

12. The automatic conveyor as claimed in claim 1, wherein suitable actuator materials are polymer networks readily swellable in aqueous solutions.

13. The automatic conveyor as claimed in claim 1, wherein the swelling agent is one of water and aqueous solutions.

14. The automatic conveyor as claimed in claim 1, wherein the actuator can be returned to an initial state through action of suitable environmental parameters and can thus be reused.

30. The automatic conveyor as claimed in claim 12, wherein said polymer networks comprise superabsorbers.

31. The automatic conveyor as claimed in claim 12, wherein said polymer networks comprise polyacrylates.

32. The automatic conveyor as claimed in claim 14, wherein suitable actuator materials are temperature-sensitive swellable polymer networks with discontinuous phase transition behavior, in particular with lower critical solution characteristics.

33. The automatic conveyor as claimed in claim 14, wherein the actuator-resetting environmental parameter is temperature.

34. The automatic conveyor as claimed in claim 33, wherein the actuator-resetting environmental parameter is temperature, applied by insertion into boiling water or steam.

15. A delivery device for delivering a substance, the delivery device having an adjustable output, wherein by operation of a suitable swelling agent an actuator triggers an automatic action comprising at least one of (a) a delay time from a user beginning to operate the device to the start of the delivery of the substance, (b) a period of time within which the substance is actually delivered, (c) a characteristic curve during delivery, (d) a volume of substance to be delivered per unit of time, and (e) a total volume of substance to be delivered, wherein at least one of the delay time, the period of time, the characteristic curve, the volume and the total volume can be adjusted by the user, and further comprising a number of serially arranged selector elements, wherein the characteristic curve is adjustable by selectively arranging said selector elements.

16. The automatic conveyor as claimed in claim 15, wherein the delay time is adjusted by varying an idling travel of the hydrogel actuator.

17. The automatic conveyor as claimed in claim 15, wherein a conveying rate or the amount conveyed per unit of time is selectable by varying at least one of the effective cross section of a swelling agent delivery line and the amount of swelling agent delivered per unit of time from the swelling agent delivery line to the actuator.

18. The automatic conveyor according to claim 17, wherein the conveying rate or the amount conveyed per unit of time are during substantially continuous conveying.

19. The automatic conveyor as claimed in claim 15, wherein the conveying rate or the amount conveyed per unit of time by the conveying device is adjustable by selecting an actuator material.

20. The automatic conveyor according to claim 19, wherein the conveying rate or the amount conveyed per unit of time are during substantially continuous conveying.

21. The automatic conveyor as claimed in claim 15, wherein the period of time within which the medium is actually conveyed is adjustable by selecting at least one of an actuator material and the a volume of actuator material.

22. The automatic conveyor as claimed in claim 15, wherein the total volume of medium to be conveyed is adjustable by one of setting the amount of swelling agent available as a whole and/or the amount of swellable actuator material available as a whole.

23. The automatic conveyor as claimed in claim 15, wherein delivery of the swelling agent to the actuator is independent of the position of the automatic conveyor.

24. The automatic conveyor as claimed in claim 23, wherein delivery of the swelling agent to the actuator is independent of the position of the automatic conveyor because a reservoir containing the swelling agent reservoir is acted upon by a hydrostatic overpressure.

25. The automatic conveyor as claimed in claim 23, wherein delivery of the swelling agent to the actuator is independent of the position of the automatic conveyor because the swelling agent is delivered from a reservoir to the actuator through a swelling agent conducting material.

26. The automatic conveyor as claimed in claim 25, wherein delivery of the swelling agent to the actuator is independent of the position of the automatic conveyor because the swelling agent is delivered from a reservoir to the actuator through a swelling agent conducting material as a result of capillary forces.

27. The automatic conveyor as claimed in claim 15, wherein the idling travel needed for realizing the time delay is reduced by the application of a counterforce.

28. The automatic conveyor as claimed in claim 27, wherein the counterforce is provided by a friction pairing.

29. The automatic conveyor as claimed in claim 15, wherein an active substance reservoir is opened, just before the start of a conveying process, by the actuator pressing the active substance reservoir onto an opening mechanism.