Device for treatment of barrier membranes

• US 7,480,530 B2
• Filed: 06/30/2003
• Issued: 01/20/2009
• Est. Priority Date: 06/30/2003
• Status: Expired due to Fees

• Current Assignee: Johnson & Johnson Consumer Companies Incorporated (Johnson & Johnson)
• Original Assignee: Johnson & Johnson Consumer Companies Incorporated (Johnson & Johnson)
• Inventors: Sun, Ying, Wu, Jeffrey M., Liu, Jue-Chen
• Primary Examiner(s): Mendez; Manuel A
• Application Number:
  US10/609,727
• Publication Number:
  US 20040267169A1
• Time in Patent Office: 2,031 Days
• Field of Search: 604/20, 604/19, 604/61, 604/501, 6048901-8921, 604/500, 424448-449, 607/120, 607/152, 607/289, 607/39, 607/43, 607/20
• US Class Current: 604/20
• CPC Class Codes: A61N 1/044 Shape of the electrode
• CPC Class Codes: A61N 1/0448 Drug reservoir
• CPC Class Codes: A61N 1/0468 Specially adapted for promoting wound healing
• CPC Class Codes: A61N 1/0492 Patch electrodes A61N1/0412, A61N1/0428 take precedence
• CPC Class Codes: A61N 1/205 for promoting a biological process
• CPC Class Codes: A61N 1/303 Constructional details electrodes for external use A61N1/0428
• CPC Class Codes: A61N 1/325 for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body electrodes for external use A61N1/0428
• CPC Class Codes: A61N 1/328 for improving the appearance of the skin, e.g. facial toning or wrinkle treatment

Abstract

The present invention features a device having a barrier membrane contacting surface, the device containing: a power source; a first conductive electrode; a second conductive electrode; and a carrier; wherein the power source is in electric communication with the first conductive electrode and the second conductive electrode, wherein the first conductive electrode and the second conductive electrode are in ionic communication with the carrier, and wherein the carrier is in communication with the barrier membrane contacting surface.

Claims

1. A device having a barrier membrane contacting surface, said device comprising:

a power source that produces conventional direct current;

a first conductive electrode that is an anode;

a second conductive electrode that is a cathode; and

a carrier;

wherein said power source is in electric communication with said first conductive electrode and said second conductive electrode, wherein said first conductive electrode and said second conductive electrode are in ionic communication with said carrier, wherein said carrier is in communication with said barrier membrane contacting surface, and wherein said device is adapted to be affixed to said barrier membrane and to deliver electric current from said first conductive electrode, through said carrier, through said barrier membrane, and through said carrier to said second conductive electrode.

2. A device of claim 1, wherein said device comprises a housing and said first conductive electrode, said second conductive electrode, and said carrier are within said housing.

3. A device of claim 1, wherein said carrier is a semi-solid.

4. A device of claim 2, wherein said housing comprises an adhesive.

5. A device of claim 3, wherein said carrier comprises an adhesive.

6. A device of claim 1, wherein the ratio of the distance between the first conductive electrode and the second conductive electrode and the distance between the first conductive electrode and the barrier membrane contacting surface is at least about 1.

7. A device of claim 3, wherein the ratio of the distance between the first conductive electrode and the second conductive electrode and the distance between the first conductive electrode and the barrier membrane contacting surface is at least about 5.

8. A device of claim 1, wherein said power source produces a voltage from about 0.1 to about 3 volts.

9. A device of claim 1, wherein said power source produces a current density of less than about 0.5 mA/cm².

10. A device of claim 8, wherein said power source produces a current density of less than about 0.5 mA/cm².

11. A method of administering electricity to a human barrier membrane, said method comprising applying to said membrane a device having a barrier membrane contacting surface, said device comprising:

a power source that produces conventional direct current;

a first conductive electrode that is an anode;

a second conductive electrode that is a cathode; and

a carrier;

wherein said power source is in electric communication with said first conductive electrode and said second conductive electrode, wherein said first conductive electrode and said second conductive electrode are in ionic communication with said carrier, wherein said carrier is in communication with said barrier membrane contacting surface, and wherein said device is adapted to be affixed to said barrier membrane and to deliver said electric current from said first conductive electrode, through said carrier, through said barrier membrane, and through said carrier to said second conductive electrode.

12. A method of claim 11, wherein the ratio of the distance between the first conductive electrode and the second conductive electrode and the distance between the first conductive electrode and the barrier membrane contacting surface is at least about 1.

13. A method of claim 11, wherein the ratio of the distance between the first conductive electrode and the second conductive electrode and the distance between the first conductive electrode and the barrier membrane contacting surface is at least about 5.

14. A method of claim 11, wherein said barrier membrane is skin.

15. A method of claim 14, wherein said skin comprises a wound.

16. A method of claim 11, wherein said barrier membrane is mucosa.

17. A method of claim 13, wherein said barrier membrane is skin.

18. A method of claim 17, wherein said skin comprises a wound.

19. A method of claim 13, wherein said barrier membrane is mucosa.

20. A method of treating a skin condition, said method comprising affixing to said skin in need of such treatment a device having a barrier membrane contacting surface, said device comprising:

a power source;

a first conductive electrode that is an anode;

a second conductive electrode that is a cathode; and

a carrier;

wherein said power source is in electric communication with said first conductive electrode and said second conductive electrode, wherein said first conductive electrode and said second conductive electrode are in ionic communication with said carrier, and wherein said carrier is in communication with said barrier membrane contacting surface, and wherein said device is adapted to be affixed to said barrier membrane and to deliver electric current from said first conductive electrode, through said carrier, through said barrier membrane, and through said carrier to said second conductive electrode.

21. A method of claim 20, wherein said skin condition is acne or rosacea.

22. A method of claim 20, wherein said skin condition is a skin infection.

23. A method of claim 20, wherein said skin condition is excess sebum secretion.

24. A method of claim 20, wherein said skin condition is excess skin pigmentation.

25. A method of claim 20, wherein said skin condition is folliculitis or pseudo-folliculitis barbae.

26. A method of claim 20, wherein said skin condition is wrinkles, sagging skin, or age-spots.