Instrument for surgically cutting tissue and method of use

• US 7,481,817 B2
• Filed: 02/13/2003
• Issued: 01/27/2009
• Est. Priority Date: 02/13/2003
• Status: Active Grant

• Current Assignee: LSI Solutions, Inc.
• Original Assignee: LSI Solutions, Inc.
• Inventors: Sauer, Jude S.
• Primary Examiner(s): Truong; Kevin T
• Assistant Examiner(s): NGUYEN, VI X
• Application Number:
  US10/365,809
• Publication Number:
  US 20040162572A1
• Time in Patent Office: 2,175 Days
• Field of Search: 606/170, 606/171, 606/180, 606/159, 606/83, 604/22, 600/564, 600/565
• US Class Current: 606/170
• CPC Class Codes: A61B 10/0283 with vacuum aspiration, e.g. caused by retractable plunger or by connected syringe A61B10/025, A61B10/0266 take precedence
• CPC Class Codes: A61B 10/04 Endoscopic instruments
• CPC Class Codes: A61B 17/320016 Endoscopic cutting instruments, e.g. arthroscopes, resectoscopes A61B10/0233, A61B17/29, A61B17/3207 take precedence
• CPC Class Codes: A61B 17/320783 through side-hole, e.g. sliding or rotating cutter inside catheter
• CPC Class Codes: A61B 2010/0225 for taking multiple samples
• CPC Class Codes: A61B 2017/00269 endoscopic mucosal resection EMR
• CPC Class Codes: A61B 2017/306 holding by means of suction
• CPC Class Codes: A61B 2017/320064 with tissue or sample retaining means

Abstract

An instrument for precisely cutting tissue to controlled dimensions (length, width, depth, and shape) is provided for the removal of tissue specimens from remote sites in the body of a patient, such as from the gastrointestinal tract, urinary tract, or vascular structures, or any tissue surface or soft tissue of the body. The instrument has a housing and a substantially flexible shaft extending from the housing to a distal end. The distal end of the instrument has an open cavity into which tissue is receivable. Suction can be communicated along the shaft to the distal end for distribution across the cavity utilizing a manifold having a grated tissue engaging surface with opening(s) for applying the suction, thereby pulling tissue adjacent to the distal end into the cavity against the tissue engaging surface of the manifold. One or more hollow needles are extendable from the housing through the shaft into the cavity to enable infusion of fluid, such as saline or a hemostatic agent, into the tissue. A blade in the distal end is extendable through the cavity over the manifold and across the opening to cut the tissue held by suction and stabilized by the needles in the cavity. The shape and depth of the tissue removed by the cuts is in accordance with the contour of the tissue engaging surface and the size and shape of the cavity at the distal end. The tissue so removed by the instrument may be for therapeutic intervention and/or represent a tissue specimen for biopsy suitable of diagnostic evaluation. The tissue edges in the patient'"'"'s body left after cutting with this instrument readily avail themselves to apposition for enhanced healing.

Claims

1. An instrument for cutting tissue comprising:

a proximal end having a housing;

a shaft extending from said housing;

a distal end coupled to said shaft;

said distal end having a cavity and an opening to said cavity;

means for providing suction along said shaft to said distal end;

means for distributing said suction at said distal end through one or more openings of a tissue engaging surface in said cavity to enable tissue adjacent said opening of said distal end to be pulled into said cavity against said tissue engaging surface; and

means for cutting said tissue engaged by said suction against said tissue engaging surface to provide a single tissue specimen in said cavity, in which said cutting means has a blade extendable over said tissue engaging surface to cut tissue extending through said opening and thereby capture said single tissue specimen engaged against said tissue engaging surface, wherein the tissue to be cut is retained in said cavity of said distal end in response to the suction provided through said one or more openings in the tissue engaging surface both before and after extension of said blade over said tissue engaging surface.

2. The instrument according to claim 1 further comprising one or more hollow needles which extend from said housing through said shaft to said distal tip in which said needles are extendable through said cavity and enable injection of fluid passing through said needles to said tissue when located in said cavity.

3. The instrument according to claim 2 further comprising means for actuating said needles in said housing to extend or retract at said distal end.

4. The instrument according to claim 2 wherein said injected fluid is capable of separating layers of said tissue.

5. The instrument according to claim 2 wherein said needles when extended assist in stabilization of tissue suctioned against said tissue engaging surface.

6. The instrument according to claim 2 wherein said fluid represents saline.

7. The instrument according to claim 2 wherein said fluid represents a therapeutic agent.

8. The instrument according to claim 2 wherein said fluid represents a hemostasis agent to minimize bleeding.

9. The instrument according to claim 2 wherein said fluid represents an analgesic.

10. The instrument according to claim 2 wherein said fluid represents one or more of epinephrine and lidocaine.

11. The instrument according to claim 2 wherein said needles are extended through said cavity prior to operation of said cutting means.

12. The instrument according to claim 1 wherein said tissue specimen cut by said cutting means has a depth in accordance with size of said cavity and contour of said tissue engaging surface in said cavity.

13. The instrument according to claim 1 wherein dimensions of said tissue specimen cut by said cutting means is in accordance with at least the size of the cavity and contour of said tissue engaging surface in said cavity.

14. The instrument according to claim 1 wherein said openings along said tissue engaging surface represent a grate capable of distributing said suction to engage the surface of said tissue adjacent said opening when said suctioning means is operated.

15. The instrument according to claim 1 wherein said means for distributing said suction comprises a manifold member having a central channel and two sets of projections each extending upwards from opposite sides of said channel towards each other, and said openings for distributing suction are formed by gaps between said projections and by a gap between said two sets of projections.

16. The instrument according to claim 1 wherein said wound in the tissue provided after operating of said cutting means results in substantially parallel opposing edges which are capable of being apposed.

17. The instrument according to claim 1 wherein said tissue specimen cut represents a tissue specimen biopsy.

18. The instrument according to claim 1 wherein said shaft is locatable along a tissue surface at remote locations in body of a patient.

19. The instrument according to claim 1 wherein said shaft is locatable in a tubular structure of the body of a patient for operating upon tissue along the lining of said tubular structure.

20. The instrument according to claim 19 wherein said tubular structure represents one of gastrointestinal tract or urinary tract.

21. The instrument according to claim 1 wherein said shaft is locatable in a vascular tract of a patient.

22. The instrument according to claim 1 wherein said means for providing suction is controlled at said proximal end.

23. The instrument according to claim 1 wherein said shaft is substantially flexible.

24. The instrument according to claim 1 further comprising means for actuating said blade in said housing to extend or retract at said distal end.

25. The instrument according to claim 1 wherein said blade represents a rotatable blade extendable over said tissue engaging surface to close said opening of said cavity when said blade is fully extended.

26. The instrument according to claim 1 wherein said blade represents an oscillating blade extendable over said tissue engaging surface in said cavity.

27. The instrument according to claim 1 wherein said shaft represents an assembly having a first section and a second section, said first section being rigid and extends from said housing, and said second section being flexible and extends from the first section to the distal end of said instrument.

28. The instrument according to claim 1 wherein said shaft of said instrument is insertable through a channel of an endoscope.

29. The instrument according to claim 1 wherein said shaft of said instrument is insertable through a tube coupled to an endoscope.

30. The instrument according to claim 1 further comprising an endoscope having a shaft with a distal end and a channel through which said shaft of said instrument extends, and said distal end of said instrument extends from said distal end of said endoscope.

31. The instrument according to claim 1 further comprising means for receiving a guide wire through said instrument to assist in locating said instrument in the body of a patient.

32. The instrument according to claim 1 wherein said distal end is locatable in breast or brain tissue of a patient.

33. The instrument according to claim 1 further comprising means for ultrasonically imaging tissue at said distal end.

34. The instrument according to claim 1 further comprising means for steering said distal end.

35. The instrument according to claim 1 further comprising means for optically imaging tissue at said distal end.

36. The instrument according to claim 1 wherein said blade when extended over said tissue engaging surface is extended along said opening of said distal end so as to close said opening to said cavity of said distal end, and thereby capture said single intact tissue specimen engaged against said tissue engaging surface.

37. An instrument for cutting tissue comprising:

a proximal end having a housing;

a shaft extending from said housing;

a distal end coupled to said shaft;

said distal end having a cavity and an opening to said cavity;

means for providing suction along said shaft to said distal end in which said distal end;

means for distributing said suction at said distal end through one or more openings of a tissue engaging surface in said cavity to enable tissue adjacent said opening of said distal end to be pulled into said cavity against said tissue engaging surface; and

means for cutting said tissue engaged against said tissue engaging surface in said cavity, wherein said cutting means utilizes a single linear edged blade oriented along a longitudinal dimension of the cavity to cut a linear slit incision across said cavity of a predetermined length and depth.

38. The instrument according to claim 37 wherein said linear edge blade member is extendible through an opening extending through said tissue engaging surface.

39. An apparatus for remotely removing a tissue specimen comprising:

a shaft coupled to a distal housing;

said distal housing having a cavity into which tissue is receivable and a surface disposed in said cavity;

said shaft having one or more paths for communicating suction to said distal housing to draw tissue against said surface, said surface having one or more openings for communicating suction to tissue; and

a blade disposed in said distal housing for cutting tissue present in said cavity when engaged by said suction against said surface, wherein the tissue is retainable in said cavity of said distal housing after extension of said blade sufficiently across said surface, wherein said distal housing further comprises an opening along one single side of said cavity into which tissue is receivable, and said surface extends in said cavity and faces said opening, and tissue is drawn by suction against said surface via said opening along said side of said cavity.

40. The apparatus according to claim 39 wherein said blade is extendable with respect to said opening of said cavity to cut said tissue and thereby capture said cut tissue in said cavity.

41. The apparatus according to claim 39 wherein the tissue is capable of being held solely by said suction at said distal end against said surface.

42. The apparatus according to claim 39 further comprising one or more needles extending through said shaft which are extendible into said tissue when engaged by said suction against said surface.

43. The apparatus according to claim 42 wherein said one or more needles enable injection of fluid into tissue while suction is being communicated to said tissue.

44. The apparatus according to claim 39 wherein said surface represents a contoured surface with said one or more openings to communicate said suction, and said tissue specimen cut by said blade has a depth in accordance with the size of said cavity and the contour of said surface.

45. The apparatus according to claim 39 wherein said blade is one of a rotatable tubular blade or an oscillating blade member translatable in the distal end to cut the tissue.

46. The apparatus according to claim 39 wherein said blade has an edge for cutting tissue, and said blade when extended across said surface said edge of said blade is shaped to provide a single slice through said tissue engaged against said tissue engaging surface.

47. An apparatus for remotely cutting tissue comprising:

a shaft coupled to a distal housing;

said distal housing having a cavity into which tissue is receivable and a surface extending in said cavity;

said shaft having one or more paths for communicating suction to said distal housing to draw tissue against said surface, said surface having one or more openings for communicating suction to tissue; and

a blade extendible in the distal housing for cutting tissue in said cavity when engaged against said surface to make a linear slit incision through said engaged tissue, wherein said distal housing further comprises an opening along one single side of said cavity into which tissue is receivable, and said surface extends in said cavity and faces said opening, and tissue is drawn by suction against said surface via said opening along said side of said cavity.

48. The apparatus according to claim 47 wherein the tissue is capable of being held solely by said suction at said distal end against said surface.

49. The apparatus according to claim 47 wherein said blade is oriented along a longitudinal dimension of the cavity.