Ocular implant with anchor and multiple openings

• US 7,488,303 B1
• Filed: 09/22/2003
• Issued: 02/10/2009
• Est. Priority Date: 09/21/2002
• Status: Expired due to Term

• Current Assignee: Glaukos Corporation
• Original Assignee: Glaukos Corporation
• Inventors: Smedley, Gregory T., Haffner, David S., Tu, Hosheng, Burns, Thomas W.
• Primary Examiner(s): Deak; Leslie R
• Application Number:
  US10/667,580
• Time in Patent Office: 1,968 Days
• Field of Search: 604 7- 10, 604/264, 604/284, 604/521, 606/107, 606/108, 623/4.1
• US Class Current: 604/8
• CPC Class Codes: A61F 9/00781 Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment drainage implants in general A61M27/002

Abstract

An implant for treating an ocular disorder has a longitudinal implant axis, an outflow portion passing therethrough, a plurality of longitudinally spaced openings therein, an inflow portion, and an anchoring member that extends from the implant and is disposed distally of the openings. The outflow portion is shaped and sized to be introduced into Schlemm'"'"'s canal of an eye at an angle, and received at least partially within Schlemm'"'"'s canal regardless of its rotational orientation about the axis during introduction. The openings allow fluid communication from a lumen within the outflow portion to a location outside the outflow portion. The inflow portion is configured to be positioned within an anterior chamber of the eye to permit fluid communication from the anterior chamber to the outflow portion. The axis extends through a trabecular meshwork of the eye and is generally orthogonal to Schlemm'"'"'s canal during the fluid communication.

Claims

1. An implant for treating an ocular disorder, said implant having a longitudinal implant axis and comprising:

an outflow portion through which said longitudinal implant axis passes, said outflow portion shaped and sized to be;

(a) introduced into Schlemm'"'"'s canal of an eye with said portion of said longitudinal implant axis at an angle to Schlemm'"'"'s canal; and

(b) received at least partially within Schlemm'"'"'s canal regardless of a rotational orientation of the outflow portion about said longitudinal implant axis during said introduction;

a plurality of longitudinally spaced openings in the outflow portion, the openings allowing fluid to communicate from a lumen within the outflow portion to a location outside the outflow portion;

an inflow portion configured to be positioned within an anterior chamber of the eye so as to permit communication of fluid from the anterior chamber to the outflow portion; and

an anchoring member extending from the implant and being disposed distally of the longitudinally spaced openings;

wherein said longitudinal implant axis extends through a trabecular meshwork of the eye and is generally orthogonal to Schlemm'"'"'s canal during said fluid communication.

2. The implant of claim 1, wherein the outflow portion has a distal end with a transverse dimension that varies along the longitudinal implant axis.

3. The implant of claim 2, wherein the distal end of the outflow portion has a generally conical shape.

4. The implant of claim 2, wherein the distal end of the outflow portion has at least one sloped surface.

5. The implant of claim 2, wherein the distal end and the outflow portion are integrally formed.

6. The implant of claim 1, wherein the anchoring member comprises a surface that is generally transverse to the longitudinal implant axis.

7. The implant of claim 1, further comprising an intermediate section between the inflow portion and the outflow portion.

8. The implant of claim 1, wherein at least a portion of the implant is configured to reside within the trabecular meshwork of the eye.

9. The implant of claim 1, wherein the outflow portion is shaped and sized to be introduced through Schlemm'"'"'s canal of the eye.

10. The implant of claim 1, wherein the implant comprises a therapeutic drug.

11. The implant of claim 10, wherein the implant comprises a polymer.

12. The implant of claim 10, wherein the implant includes a first portion and a second portion that is appended from the first portion, and wherein the first portion includes the lumen and the second portion carries the therapeutic drug.

13. The implant of claim 10, wherein at least a portion of the implant is coated with the therapeutic drug.

14. The implant of claim 10, wherein the implant comprises a biocompatible material with the therapeutic drug coated thereon.