Method and apparatus for replacing a mitral valve and an aortic valve with a single homograft

• US 7,488,346 B2
• Filed: 01/18/2005
• Issued: 02/10/2009
• Est. Priority Date: 01/21/2004
• Status: Expired due to Fees

• Current Assignee: Cleveland Clinic Foundation
• Original Assignee: Cleveland Clinic Foundation
• Inventors: Navia, Jose Luis
• Primary Examiner(s): Ganesan; Suba
• Application Number:
  US11/037,499
• Publication Number:
  US 20050187617A1
• Time in Patent Office: 1,484 Days
• Field of Search: 623/1.26, 623 212- 219, 623/14.13, 623/904, 623/918, 623/922, 623 2372- 2376
• US Class Current: 623/1.26
• CPC Class Codes: A61F 2/2412 with soft flexible valve members, e.g. tissue valves shaped like natural valves check valves with flexible valve members in general F16K15/14
• CPC Class Codes: Y10S 623/904 Heart

Abstract

A method and apparatus for replacing both the native mitral valve and the native aortic valve in a heart with a stentless bioprosthetic graft is provided. The bioprosthetic graft comprises a harvested homograft that includes a mitral valve portion and an aortic valve portion, and an extension portion made of a biocompatible material. The extension portion is sutured to the homograft and is for suturing to the left atrial wall of the heart to close an incision in the left atrial wall following implantation of the mitral valve portion and the aortic valve portion of the homograft.

Claims

1. A method for replacing a native mitral valve and a native aortic valve with a single bioprosthetic graft, said method comprising the steps of:

harvesting a homograft that includes both a mitral valve portion and an aortic valve portion;

resecting the native mitral and aortic valves from the heart;

suturing a biocompatible extension portion to the homograft;

suturing a free edge of at least one of an anterior leaflet and a posterior leaflet of the mitral valve portion of the homograft to at least one of a native anterior leaflet and a native posterior leaflet of the native mitral valve with the at least one of the anterior and posterior leaflets being operatively attached to at least one native chordae tendinae through the at least one native anterior and posterior leaflets;

suturing the aortic valve portion of the homograft in place of the native aortic valve; and

suturing the extension portion to the left atrial wall of the heart to close the left atrial wall.

2. The method of claim 1, wherein the homograft includes an aortic wall, and the heart has at least one native coronary ostium button, and including the step of attaching at least one of the native coronary ostium buttons to the aortic wall during implantation of the homograft.

3. The method of claim 1, wherein at least one of the mitral valve portion and the aortic valve portion of the homograft has an annulus with associated myocardium, and including the step of trimming at least a portion of the myocardium from at least one annulus before implantation.

4. The method of claim 1, wherein the homograft includes at least one fibrous trigone, and including the step of aligning the fibrous trigone with a native fibrous trigone of the heart during implantation.

5. A method for replacing a native mitral valve and a native aortic valve with a single bioprosthetic graft, the native mitral valve including native anterior and posterior leaflets having corresponding native chordae tendinea, said method comprising the steps of:

harvesting a homograft that includes both a mitral valve portion and an aortic valve portion;

resecting at least a portion of the native aortic valve from the heart;

partially resecting the native mitral valve from the heart while maintaining at least one native free-edge leaflet attached to at least one native chordae tendinea;

suturing a biocompatible extension portion to the homograft;

suturing at least one of an anterior leaflet and a posterior leaflet of the mitral valve portion of the homograft to at least one native free-edge leaflet of the native mitral valve with the at least one of the anterior and posterior leaflets being operatively attached to at least one native chordae tendinae through the at least one native free-edge leaflet;

suturing the aortic valve portion of the homograft in place of the native aortic valve; and

suturing the extension portion to the left atrial wall of the heart to close the left atrial wall.