Invisible antimicrobial glove and hand antiseptic

• US 7,488,757 B2
• Filed: 03/24/2004
• Issued: 02/10/2009
• Est. Priority Date: 03/24/2003
• Status: Active Grant

• Current Assignee: Becton, Dickinson & Co
• Original Assignee: Becton, Dickinson & Co
• Inventors: Hunt, Donald Edward, Hoang, Minh Quang
• Primary Examiner(s): Pak; John
• Assistant Examiner(s): Schlientz; Nathan W
• Application Number:
  US10/550,184
• Publication Number:
  US 20060263323A1
• Time in Patent Office: 1,784 Days
• Field of Search: 424/404, 424/405, 510/132, 514/483, 514/545, 514/552, 514/635, 514/636, 514/637, 514/642, 514/724, 514/738
• US Class Current: 514/635
• CPC Class Codes: A61K 2800/28 Rubbing or scrubbing compositions; Peeling or abrasive compositions; Containing exfoliants
• CPC Class Codes: A61K 2800/54 Polymers characterized by specific structures/properties
• CPC Class Codes: A61K 2800/5426 cationic
• CPC Class Codes: A61K 2800/5922 At least two compounds being classified in the same subclass of A61K8/18
• CPC Class Codes: A61K 8/34 Alcohols
• CPC Class Codes: A61K 8/342 Alcohols having more than seven atoms in an unbroken chain
• CPC Class Codes: A61K 8/37 Esters of carboxylic acids
• CPC Class Codes: A61K 8/416 Quaternary ammonium compounds A61K8/35 takes precedence
• CPC Class Codes: A61K 8/43 Guanidines
• CPC Class Codes: A61K 8/46 containing sulfur A61K8/44 takes precedence
• CPC Class Codes: A61K 8/731 Cellulose; Quaternized cellulose derivatives
• CPC Class Codes: A61K 8/8176 Homopolymers of N-vinyl-pyrrolidones. Compositions of derivatives of such polymers
• CPC Class Codes: A61K 8/86 Polyethers
• CPC Class Codes: A61K 8/922 of vegetable origin
• CPC Class Codes: A61P 31/00 Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
• CPC Class Codes: A61Q 17/005 Antimicrobial preparations
• CPC Class Codes: A61Q 19/10 Washing or bathing preparations
• CPC Class Codes: B08B 3/04 Cleaning involving contact with liquid

Abstract

An alcohol based hand surgical scrub, which includes cationic anti-microbial agent preservatives, cationic polymer film-forming agents and a skin emollient, and provides a long term residual, anti-microbial “invisible glove” on the skin. The composition provides an immediate reduction in bacterial microbes. The polymer system creates an invisible film on the skin following solvent evaporation. This invisible film provides a lasting anti-microbial barrier on the skin which acts to prevent microbial growth.

Claims

1. A surgical scrub composition comprising, in weight percent of the total composition:

(a) from about 0.1% to about 5% of 1-docosanol;

(b) from about 0.05% to about 5% of chlorhexidine digluconate;

(c) from about 60% to about 95% of alcohol;

(d) from about 0.1% to about 5% of glycerin;

(e) from about 0.1% to about 5% of a 25% active solution of behenyl trimethyl ammonium methosulfate in cetearyl alcohol;

(f) from about 0.1% to about 5% of isopropyl palmitate;

(g) from about 0.03% to about 5% of a preservative selected from the group consisting of methylparaben and propylparaben; and

(h) from about 1% to about 35% of purified water.

2. A method of using a surgical scrub composition for hand antisepsis comprising:

(a) applying a cleansing liquid to the skin;

(b) scrubbing the skin with an anti-microbial scrub solution;

(c) rinsing the anti-microbial scrub solution from the skin; and

(d) applying an effective amount of a surgical scrub composition according to claim 1.