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Self-assembly and mineralization of peptide-amphiphile nanofibers

  • US 7,491,690 B2
  • Filed: 11/14/2002
  • Issued: 02/17/2009
  • Est. Priority Date: 11/14/2001
  • Status: Expired due to Fees
First Claim
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1. A peptide amphiphile composition comprising a peptide amphiphile selected from the group consisting ofCCCCGGGSRGD (SEQ ID NO:

  • 2),CCCCGGGSRGDS (SEQ ID NO;

         17),CCCCGGGSKGE (SEQ ID NO;

         11),CCCCGGGEIKVAV (SEQ ID NO;

         16),AAAAGGGSRGD (SEQ ID NO;

         9),AAAAGGGSKGE (SEQ ID NO;

         12), andGGGSRGD (SEQ ID NO;

         7),wherein the serine residue in the peptide amphiphile is optionally phosphorylated and wherein a C10-C22 hydrocarbon component is attached to the N-terminus of the peptide component, which directs said composition to form a cylindrical micelle in an aqueous medium.

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