MRI method for reducing artifacts using RF pulse at offset frequency

• US 7,495,439 B2
• Filed: 04/27/2007
• Issued: 02/24/2009
• Est. Priority Date: 04/27/2007
• Status: Active Grant

• Current Assignee: The General Hospital Corporation (Mass General Brigham, Inc.)
• Original Assignee: The General Hospital Corporation (Mass General Brigham, Inc.)
• Inventors: Wiggins, Christopher John
• Primary Examiner(s): Shrivastav; Brij
• Assistant Examiner(s): Fetzner; Tiffany A
• Application Number:
  US11/741,252
• Publication Number:
  US 20080265883A1
• Time in Patent Office: 669 Days
• Field of Search: 324300-322, 600410-422, 427/17, 430/270.15
• US Class Current: 324/309
• CPC Class Codes: G01R 33/5607 by reducing the NMR signal of a particular spin species, e.g. of a chemical species for fat suppression, or of a moving spin species for black-blood imaging
• CPC Class Codes: G01R 33/5615 Echo train techniques involving acquiring plural, differently encoded, echo signals after one RF excitation, e.g. using gradient refocusing in echo planar imaging [EPI], RF refocusing in rapid acquisition with relaxation enhancement [RARE] or using both RF and gradient refocusing in gradient and spin echo imaging [GRASE]
• CPC Class Codes: G01R 33/5616 using gradient refocusing, e.g. EPI
• CPC Class Codes: G01R 33/5617 using RF refocusing, e.g. RARE
• CPC Class Codes: G01R 33/56536 due to magnetic susceptibility variations
• CPC Class Codes: G01R 33/56554 caused by acquiring plural, differently encoded echo signals after one RF excitation, e.g. correction for readout gradients of alternating polarity in EPI

Abstract

A method for magnetic resonance imaging includes performing a preparatory stage of a MR pulse sequence with an MRI system in which a non-selective RF preparatory pulse is used having a bandwidth such that any spin species having corresponding Larmor frequencies within that bandwidth are affected and the bandwidth is centered at a selected frequency which is offset from a nominal Larmor frequency of the desired spin species being imaged. A time period (TI) elapses during which longitudinal spin magnetization recovers; and then an imaging stage is performed in which an RF excitation pulse is generated to produce transverse spin magnetization of the desired spin species, and in which a set of NMR signals are acquired. An image is reconstructed using the acquired set of NMR signals, and the reconstructed image has reduced artifacts due to B₀ field inhomogeneities caused by magnetic susceptibility effects.

Claims

1. A method for producing an image of a desired spin species with a magnetic resonance imaging system, the image having reduced artifacts due to B0 field inhomogeneities due to magnetic susceptibility effects, the method comprising:

a) performing a preparatory stage of an MR pulse sequence with the MRI system in which a non-selective RF preparatory pulse is produced having a bandwidth centered at a selected frequency which is offset from a nominal Larmor frequency of the desired spin species being imaged to increase a spectral coverage of the non-selective RF preparatory pulse over a non-selective RF preparatory pulse having a bandwidth centered at the nominal Larmor frequency, and a time period (TI) elapses during which longitudinal spin magnetization recovers; and

b) performing an imaging stage of the MR pulse sequence when the TI elapses in which an RF excitation pulse is generated to produce transverse spin magnetization of the desired spin species, and in which a set of NMR signals are acquired that sample k-space; and

c) reconstructing an image using the acquired NMR signals.

2. The method of claim 1 wherein the MR pulse sequence is a modified MP-RAGE pulse sequence.

3. The method of claim 1 wherein the RF preparatory pulse is an inversion pulse.

4. The method of claim 1 wherein the RF preparatory pulse is applied in the absence of gradients.

5. The method of claim 1 wherein the desired spin species being imaged is hydrogen in water and the bandwidth of the RF preparatory pulse inverts hydrogen in water and in fat.

6. The method of claim 1, wherein the reconstructed image produced by step c) includes fewer artifacts compared to an image reconstructed using NMR signals acquired using the same MR pulse sequence and the same bandwidth of the RE preparatory pulse, but with the RF preparatory pulse having a center frequency at the nominal the Larmor frequency of the desired spin species being imaged.

7. The method of claim 1 wherein the magnetic resonance imaging system has a magnetic polarizing field ≧

3.0 T.

8. The method of claim 1 wherein the magnetic resonance imaging system has a magnetic polarizing field of 7.0 T.

9. The method of claim 8 wherein the amount of the frequency offset is approximately 200 Hz.