×

Water-soluble rhodamine dye conjugates

  • US 7,504,496 B2
  • Filed: 02/14/2005
  • Issued: 03/17/2009
  • Est. Priority Date: 11/03/1999
  • Status: Expired due to Fees
First Claim
Patent Images

1. A labeled nucleoside/tide or nucleoside/tide analog comprising a rhodamine dye conjugated by a linker (L′

  • ) to a nucleoside/tide or nucleoside/tide analog (NUC), wherein;

    the rhodamine is a rhodamine-type parent xanthene having attached to the xanthene C9 carbon a phenyl group, wherein the phenyl group is further substituted with (i) a carboxy group or a sulfonate group or a salt thereof;

    (ii) one to three substituted or unsubstituted aminopyridinium groups; and

    (iii) a substituted or unsubstituted alkylthio or arylthio group; and

    the nucleoside/tide or nucleoside/tide analog and linker taken together comprise the structure;

View all claims
  • 7 Assignments
Timeline View
Assignment View
    ×
    ×