Transluminal mitral annuloplasty
First Claim
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1. A method of providing a therapeutic compressive force against a tissue structure which is adjacent to a vessel wall, comprising the steps of:
- advancing an elastically deformable device over a guidewire and into the vessel;
rotating at least a part of a forming element within the device to cause the device to elastically deform by increasing a tension of the forming element within the device, thereby altering a radius of curvature of the device;
exerting a force against the adjacent tissue structure with the elastically deformed device; and
implanting the device within the vessel.
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Abstract
A mitral annuloplasty and left ventricle restriction device is designed to be transvenously advanced and deployed within the coronary sinus and in some embodiments other coronary veins The device places tension on adjacent structures, reducing the diameter and/or limiting expansion of the mitral annulus and/or limiting diastolic expansion of the left ventricle. These effects may be beneficial for patients with dilated cardiomyopathy.
266 Citations
11 Claims
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1. A method of providing a therapeutic compressive force against a tissue structure which is adjacent to a vessel wall, comprising the steps of:
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advancing an elastically deformable device over a guidewire and into the vessel; rotating at least a part of a forming element within the device to cause the device to elastically deform by increasing a tension of the forming element within the device, thereby altering a radius of curvature of the device; exerting a force against the adjacent tissue structure with the elastically deformed device; and implanting the device within the vessel. - View Dependent Claims (2, 3, 4, 5)
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6. A method of providing a therapeutic compressive force against a tissue structure which is adjacent to a vessel wall, comprising the steps of:
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advancing a one-piece bendable device over a guidewire and into the vessel, the device being bendable along its length from a first end to a second end and having a long axis extending along the length; rotating, about the long axis, at least a part of a forming element within the device to bend at least a portion of the device between the first end and the second end, thereby altering a radius of curvature of the device for exerting a force against the adjacent tissue structure; and implanting the device within the vessel. - View Dependent Claims (7, 8, 9, 10, 11)
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Specification