Acute and chronic electrical signal therapy for obesity

• US 7,512,442 B2
• Filed: 10/28/2005
• Issued: 03/31/2009
• Est. Priority Date: 12/11/2000
• Status: Expired due to Fees

• Current Assignee: Tylerton International Inc.
• Original Assignee: Metacure NV
• Inventors: Ben-Haim, Shlomo, Darvish, Nissim, Mika, Yuval, Ben Arie, Yaakov, Flesler, Melina, Belsky, Ziv
• Primary Examiner(s): Layno; Carl H.
• Assistant Examiner(s): MORALES, JON ERIC C
• Application Number:
  US11/260,971
• Publication Number:
  US 20060074459A1
• Time in Patent Office: 1,250 Days
• Field of Search: 607/40, 607/133, 607/41
• US Class Current: 607/40
• CPC Class Codes: A61N 1/05 for implantation or insertion into the body, e.g. heart electrode A61N1/06 takes precedence
• CPC Class Codes: A61N 1/08 Arrangements or circuits for monitoring, protecting, controlling or indicating for external stimulators A61N1/3603; for implantable neurostimulators A61N1/36128; for heart stimulators A61N1/37; for defibrillators A61N1/3925
• CPC Class Codes: A61N 1/306 Arrangements where at least part of the apparatus is introduced into the body
• CPC Class Codes: A61N 1/326 for promoting growth of cells, e.g. bone cells
• CPC Class Codes: A61N 1/36007 of urogenital or gastrointestinal organs, e.g. for incontinence control

Abstract

Apparatus is provided for treating a condition such as obesity. The apparatus includes a set of one or more electrodes, which are adapted to be applied to one or more respective sites in a vicinity of a body of a stomach of a patient. A control unit is adapted to drive the electrode set to apply to the body of the stomach a signal, configured such that application thereof increases a level of contraction of muscle tissue of the body of the stomach, and decreases a cross sectional area of a portion of the body of the stomach for a substantially continuous period greater than about 3 seconds.

Claims

1. Apparatus for treating a condition, comprising:

a set of one or more electrodes, configured to be applied to one or more respective sites in a vicinity of a stomach of a patient; and

a control unit, configured to;

drive the electrode set to apply an electrical signal to the sites, and

configure the signal to decrease a cross-sectional area of at least a portion of the stomach, and to maintain a blood sugar level of the patient within a desired range,

wherein the electrode set is configured to be applied in contact with muscle tissue of the stomach.

2. The apparatus according to claim 1, and comprising a sensor, configured to sense the blood sugar level and generate an indication of the level, wherein the control unit is configured to adjust the signal responsive to the indication in order to maintain the blood sugar level within the desired range.

3. The apparatus according to claim 2, wherein the control unit is configured to withhold driving the electrode set to apply the signal when the blood sugar level is below a determined threshold.

4. The apparatus according to claim 1, wherein the signal is an Excitable-Tissue Control (ETC) signal, and wherein the control unit is configured to apply the ETC signal to the sites.

5. The apparatus according to claim 4, wherein the control unit is configured to drive the electrode set to apply the ETC signal as a series of biphasic pulses.

6. The apparatus according to claim 4, wherein the control unit is configured to configure the ETC signal to have a duration of at least 1 second.

7. The apparatus according to claim 6, wherein the control unit is configured to configure the ETC signal to have a duration of at least 3 seconds.

8. The apparatus according to claim 1, wherein the signal is excitatory, and wherein the control unit is configured to apply the excitatory signal to the sites.

9. Apparatus for treating a condition, comprising:

a set of one or more electrodes, configured to be applied to one or more respective sites in a vicinity of a stomach of a patient; and

a control unit, configured to;

drive the electrode set to apply an electrical signal to the sites,

configure the signal to decrease a cross-sectional area of at least a portion of the stomach, and to maintain a blood sugar level of the patient within a desired range, and

configure the signal such that application thereof decreases a volume of the stomach.

10. Apparatus for treating a condition, comprising:

a set of one or more electrodes, configured to be applied to one or more respective sites in a vicinity of a stomach of a patient; and

a control unit, configured to;

drive the electrode set to apply an electrical signal to the sites, and

configure the signal to maintain a blood sugar level of the patient within a desired range,

wherein the electrode set is configured to be applied in contact with muscle tissue of the stomach.

13. The apparatus according to claim 10, and comprising a sensor, configured to sense the blood sugar level and generate an indication of the level, wherein the control unit is configured to adjust the signal responsive to the indication in order to maintain the blood sugar level within the desired range.

14. The apparatus according to claim 10, wherein the signal is an Excitable-Tissue Control (ETC) signal, and wherein the control unit is configured to apply the ETC signal to the sites.

15. The apparatus according to claim 10, wherein the control unit is configured to configure the signal to have a duration of at least 3 seconds.

16. The apparatus according to claim 10, wherein the signal is excitatory, and wherein the control unit is configured to apply the excitatory signal to the sites.

11. Apparatus for treating a condition, comprising:

a set of one or more electrodes, configured to be applied to one or more respective sites in a vicinity of a stomach of a patient; and

a control unit, configured to;

drive the electrode set to apply an electrical signal to the sites,

configure the signal to maintain a blood sugar level of the patient within a desired range, and

configure the signal to modify contraction of muscle tissue of the stomach.

12. The apparatus according to claim 11, wherein the control unit is configured to configure the signal to increase a level of the contraction of the muscle tissue.

17. Apparatus for treating a condition, comprising:

a set of one or more electrodes, configured to be applied to one or more respective sites in a vicinity of a stomach of a patient; and

a control unit, configured to;

drive the electrode set to apply an electrical signal to the sites,

configure the signal to maintain a blood sugar level of the patient within a desired range, and

configure the signal such that application thereof decreases a volume of the stomach.