Method of preparing a packaged antimicrobial medical device
First Claim
1. A method of making a packaged medical device comprising the steps of:
- providing a package comprising an inner surface that is substantially free of an antimicrobial agent;
positioning a medical device within the package, said medical device comprising one or more surfaces having an antimicrobial agent disposed thereon, said antimicrobial agent being selected from the group consisting of halogenated hydroxyl ethers, acyloxydiphenyl ethers, and combinations thereof;
heating said package at a temperature between about 22°
C. and about 70°
C. at a pressure between about 1.8 kPa and atmospheric pressure; and
vapor transferring an effective amount of the antimicrobial agent from the medical device to the inner surface of the package, while retaining an effective amount of said antimicrobial agent on the medical device, to thereby substantially inhibit bacterial colonization on the medical device and the inner surface of the package.
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Accused Products
Abstract
A method of making a packaged antimicrobial suture comprising the steps of providing a containment compartment that is substantially free of an antimicrobial agent; positioning a suture within the containment compartment, said suture comprising one or more surfaces having an antimicrobial agent disposed thereon, said antimicrobial agent being selected from the group consisting of halogenated hydroxyl ethers, acyloxydiphenyl ethers, and combinations thereof; placing the containment compartment having the suture in an outer package; and subjecting the outer package, the containment compartment and the suture to time, temperature and pressure conditions sufficient to vapor transfer an effective amount of the antimicrobial agent from the suture to the containment compartment, while retaining an effective amount of said antimicrobial agent on the suture, thereby substantially inhibiting bacterial colonization on the suture and the containment compartment.
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Citations
7 Claims
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1. A method of making a packaged medical device comprising the steps of:
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providing a package comprising an inner surface that is substantially free of an antimicrobial agent; positioning a medical device within the package, said medical device comprising one or more surfaces having an antimicrobial agent disposed thereon, said antimicrobial agent being selected from the group consisting of halogenated hydroxyl ethers, acyloxydiphenyl ethers, and combinations thereof; heating said package at a temperature between about 22°
C. and about 70°
C. at a pressure between about 1.8 kPa and atmospheric pressure; andvapor transferring an effective amount of the antimicrobial agent from the medical device to the inner surface of the package, while retaining an effective amount of said antimicrobial agent on the medical device, to thereby substantially inhibit bacterial colonization on the medical device and the inner surface of the package. - View Dependent Claims (2)
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3. A method of making a packaged antimicrobial suture comprising the steps of:
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providing a containment compartment that is substantially free of an antimicrobial agent; positioning a suture within the containment compartment, said suture comprising one or more surfaces having an antimicrobial agent disposed thereon, said antimicrobial agent being selected from the group consisting of halogenated hydroxyl ethers, acyloxydiphenyl ethers, and combinations thereof; placing the containment compartment having the suture in an outer package; heating said package at a temperature between about 22°
C. and about 70°
C. at a pressure between about 1.8 kPa and atmospheric pressure; andvapor transferring an effective amount of the antimicrobial agent from the suture to an inner surface of the containment compartment, while retaining an effective amount of said antimicrobial agent on the suture, thereby substantially inhibiting bacterial colonization on the suture and the containment compartment. - View Dependent Claims (4, 5, 6, 7)
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Specification