Photoacoustic analyzer of region of interest in a human body
First Claim
1. A device for non-invasive analysis in a region of interest of a body medium, the device comprising:
- (a) an illuminator configured to produce pulsed light of at least two different wavelengths;
(b) an acoustic unit configured and operable to collect acoustic radiation and generate data indicative thereof, the acoustic unit being operable to collect acoustical radiation at a location on a body surface generated in the region of interest by a photoacoustic effect when the region of interest is irradiated with the illuminating pulsed light and generate measured data indicative of the received radiation; and
(c) a processor configured to receive the measured data, and analyze the received data to determine at least one desired characteristic of the region of interest, said at least one desired parameter comprising a cross-sectional dimension of the region of interest, the processor being preprogrammed to carry out at least one of the following;
i) determining time variations of at least one predetermined parameter of a time dependent acoustic signal in the collected acoustic radiation for each of said at least two wavelengths, and determining oxygen saturation level in the region of interest;
ii) operating a plurality of acoustic elements of the acoustic unit to thereby define a focal volume for the acoustic radiation collection, said focal volume matching dimensions of the region of interest.
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Accused Products
Abstract
A method and apparatus are presented for non-invasively monitoring at least one characteristic of a region of interest in a body. The body is illuminated by pulsed light to induce a photoacoustic effect. Acoustic radiation is detected, and measured data indicative thereof is generated. The photoacoustic effect is controlled by carrying out at least one of the following: providing the pulsed light of at least two different wavelength, analyzing the measured data to determine time variations of at least one predetermined parameter of a time dependent acoustic signal for each of wavelength, and determining oxygen saturation level in the region of interest; and operating a plurality of acoustic elements configured for detection of the acoustic radiation, to thereby define a focal volume for acoustic radiation detection to match dimensions of the region of interest.
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Citations
40 Claims
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1. A device for non-invasive analysis in a region of interest of a body medium, the device comprising:
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(a) an illuminator configured to produce pulsed light of at least two different wavelengths; (b) an acoustic unit configured and operable to collect acoustic radiation and generate data indicative thereof, the acoustic unit being operable to collect acoustical radiation at a location on a body surface generated in the region of interest by a photoacoustic effect when the region of interest is irradiated with the illuminating pulsed light and generate measured data indicative of the received radiation; and (c) a processor configured to receive the measured data, and analyze the received data to determine at least one desired characteristic of the region of interest, said at least one desired parameter comprising a cross-sectional dimension of the region of interest, the processor being preprogrammed to carry out at least one of the following; i) determining time variations of at least one predetermined parameter of a time dependent acoustic signal in the collected acoustic radiation for each of said at least two wavelengths, and determining oxygen saturation level in the region of interest; ii) operating a plurality of acoustic elements of the acoustic unit to thereby define a focal volume for the acoustic radiation collection, said focal volume matching dimensions of the region of interest. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36)
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37. A device for non-invasive analysis of a region of interest in a body medium, the device comprising:
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(a) an illumination unit producing pulsed light; (b) an acoustic unit configured to collect acoustic radiation and generate measured data indicative thereof, the acoustic unit comprising a plurality of independent acoustic elements, each acoustic element producing a measured signal in response to and indicative of collected acoustic radiation at a location on a body surface generated in the body medium by a photoacoustic effect when the acoustic unit is applied to the body surface and the body medium is irradiated with the illuminating light; and (c) a processor configured to operate the acoustic unit to thereby define a focal volume for the acoustic radiation collection to match dimensions of the region of interest and to determine a cross-sectional dimension of the region of interest. - View Dependent Claims (38, 39)
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40. A device for non-invasive pulse oximetry in a region of interest of a body, the device comprising:
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(a) an illumination unit configured and operable to produce pulsed light of at least two different wavelengths; (b) an acoustic unit configured to generate data indicative of received acoustic radiation, the acoustic unit being operable to receive acoustical radiation at a location on a body surface generated in the region of interest by a photoacoustic effect when the region of interest is irradiated with the illuminating pulsed light and generate measured data indicative of the received radiation; and (c) a processor configured to receive and analyze the measured data, to determine time variations of at least one predetermined parameter of the time dependent acoustic signal for each of said at least two wavelengths, and determine a cross-sectional dimension of the region of interest and determine oxygen saturation level in the region of interest.
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Specification