Delivery of CRT therapy during AT/AF termination

• US 7,515,959 B2
• Filed: 03/31/2005
• Issued: 04/07/2009
• Est. Priority Date: 03/31/2005
• Status: Active Grant

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Hess, Michael F.
• Primary Examiner(s): Layno; Carl H.
• Assistant Examiner(s): MORALES, JON ERIC C
• Application Number:
  US11/096,511
• Publication Number:
  US 20060224193A1
• Time in Patent Office: 1,468 Days
• Field of Search: None
• US Class Current: 607/14
• CPC Class Codes: A61N 1/3622 comprising two or more electrodes co-operating with different heart regions
• CPC Class Codes: A61N 1/3627 for treating a mechanical deficiency of the heart, e.g. congestive heart failure or cardiomyopathy
• CPC Class Codes: A61N 1/3925 Monitoring; Protecting
• CPC Class Codes: A61N 1/3956 Implantable devices for applying electric shocks to the heart, e.g. for cardioversion
• CPC Class Codes: A61N 1/39622 Pacing therapy

Abstract

In some embodiments, a method for operating a cardiac rhythm management device may include one or more of the following steps: (a) sensing atrial depolarizations through an implanted atrial electrode, (b) administering a sequential CRT pacing therapy in a sequential CRT pacing mode to a left and right ventricle of a heart of a patient via implanted ventricular electrodes in a sequential bi-ventricular fashion, (c) switching from the sequential CRT pacing mode to a simultaneous CRT pacing mode, (d) administering a simultaneous CRT pacing therapy in the simultaneous CRT pacing mode to the left and right ventricle in a simultaneous bi-ventricular fashion, (e) analyzing the sensed atrial depolarizations to detect the presence of an atrial arrhythmia, (f) analyzing the sensed atrial depolarizations while in the sequential CRT pacing mode to detect the presence of atrial arrhythmia, and (g) sensing ventricular depolarizations of the left and the right ventricle.

Claims

1. A method for operating a cardiac rhythm management device, comprising:

sensing atrial depolarizations through an implanted atrial electrode;

administering a sequential cardiac resynchronization therapy (CRT) pacing therapy in a sequential CRT pacing mode to a left and right ventricle of a heart of a patient via implanted ventricular electrodes in a sequential bi-ventricular fashion;

detecting an atrial arrhythmia in response to the sensed atrial depolarizations according to a first threshold for determination of atrial arrhythmia;

switching from the sequential CRT pacing mode to a simultaneous CRT pacing mode in response to detecting the atrial arrhythmia according to the first threshold;

administering a simultaneous CRT pacing therapy in the simultaneous CRT pacing mode to the left and right ventricle in a simultaneous bi-ventricular fashion; and

analyzing the sensed atrial depolarizations during the simultaneous CRT pacing therapy to confirm the presence of the detected atrial arrhythmia according to a second threshold for determination of the atrial arrhythmia, the second threshold higher than the first threshold.

2. The method of claim 1, further including analyzing the sensed atrial depolarizations while in the sequential CRT pacing mode to detect the presence of atrial arrhythmia.

3. The method of claim 1, further including sensing ventricular depolarizations of the left and the right ventricle.

4. The method of claim 1, further including providing an atrial pacing therapy when no atrial depolarizations are sensed for a predetermined amount of time.

5. The method of claim 1, further including switching from the simultaneous CRT pacing mode to the sequential CRT pacing mode when the presence of atrial arrhythmia is not detected.

6. The method of claim 1, wherein switching from the simultaneous CRT pacing mode to the sequential CRT pacing mode further comprises switching to no ventricular sense response.

7. The method of claim 1 further comprising:

switching to a therapy CRT mode in response to confirming the detected atrial arrhythmia, the therapy CRT mode including one of a single-sided CRT pacing mode and a simultaneous CRT pacing mode, the therapy CRT mode further comprising no ventricular sense response; and

delivering an atrial therapy during the therapy CRT mode.

8. A method for operating a cardiac rhythm management device, comprising:

administering a sequential cardiac resynchronization therapy (CRT) pacing therapy in a sequential CRT pacing mode to a left and right ventricle of a heart of a patient via implanted ventricular electrodes in a sequential bi-ventricular fashion;

detecting an atrial arrhythmia according to a first threshold for determination of atrial arrhythmia;

switching from the sequential CRT pacing mode to a modified CRT pacing mode in response to the detected atrial arrhythmia;

administering a modified CRT pacing therapy in the modified CRT pacing mode, the modified CRT pacing therapy being one of a simultaneous CRT pacing therapy and a single-sided pacing therapy, the simultaneous CRT pacing therapy being administered to the left and right ventricle in a simultaneous bi-ventricular fashion, the single-sided CRT pacing therapy being administered to one of the left and right ventricles;

confirming the detected atrial arrhythmia according to a second threshold for determination of atrial arrhythmia during administration of the modified CRT therapy, the second threshold higher than the first threshold; and

administering an atrial electrical stimulation therapy via an implanted atrial electrode to an atrium of the patient in the presence of an atrial arrhythmia.

9. The method of claim 8, wherein the atrial electrical stimulation therapy includes at least one of anti-tachy pacing, atrial cardioversion, and atrial defibrillation.

10. The method of claim 8, further including sensing atrial depolarizations.

11. The method of claim 8, wherein switching from the sequential CRT pacing mode to the modified CRT pacing mode occurs before administering the atrial electrical stimulation therapy.

12. The method of claim 8, further including sensing ventricular depolarizations of the left and the right ventricle, and wherein the sequential CRT pacing therapy is applied upon sensing depolarization of the right or left ventricle.

13. The method of claim 8, further including sensing ventricular depolarizations of the ventricles, and wherein one of the sequential CRT pacing therapy and the modified pacing therapy is administered when no ventricular depolarizations are sensed for a predetermined amount of time.

14. The method of claim 8, further including switching from the modified CRT pacing mode to the sequential CRT pacing mode after administering the electrical atrial stimulation therapy.

15. A system for operating a cardiac rhythm management device, comprising:

means for sensing atrial depolarizations through an implanted atrial electrode;

means for administering a sequential cardiac resynchronization therapy (CRT) pacing therapy in a sequential CRT pacing mode to a left and right ventricle of a heart of a patient via implanted ventricular electrodes in a sequential bi-ventricular fashion;

means for detecting an atrial arrhythmia according to a first threshold for determination of atrial arrhythmia;

means for switching from the sequential CRT pacing mode to a single-sided CRT pacing mode in response to the detected atrial arrhythmia;

means for administering a single-sided CRT pacing therapy in the single-sided CRT pacing mode to one of the left and right ventricle; and

means for analyzing the sensed atrial depolarizations during the single-sided CRT pacing therapy to confirm the presence of the detected atrial arrhythmia according to a second threshold for determination of the atrial arrhythmia, the second threshold higher than the first threshold.

16. The system of claim 15, further including means for analyzing the sensed atrial depolarizations while in the sequential CRT pacing mode to detect the presence of atrial arrhythmia.

17. The system of claim 16, wherein the analysis to detect the presence of an atrial arrhythmia while in the sequential CRT pacing mode is a preliminary detection analysis.

18. The system of claim 15, further including sensing ventricular depolarizations of the ventricles.

19. The system of claim 15, further including providing an atrial pacing therapy when no atrial depolarizations are sensed for a predetermined amount of time.

20. The system of claim 15, further including switching from the single-sided CRT pacing mode to the sequential CRT pacing mode when the presence of atrial arrhythmia is not detected.

21. The system of claim 15, wherein the means for switching from the sequential CRT pacing mode to the single-sided CRT pacing mode comprises means for switching to no ventricular sense response.

22. A method for operating a cardiac rhythm management device, comprising:

sensing atrial depolarizations through an implanted atrial electrode;

administering a sequential cardiac resynchronization therapy (CRT) pacing therapy in a sequential CRT pacing mode to a left and right ventricle of a heart of a patient via implanted ventricular electrodes in a sequential bi-ventricular fashion;

detecting an atrial arrhythmia in response to the sensed atrial depolarizations according to a first threshold for determination of the atrial arrhythmia;

switching from the sequential CRT pacing mode to a modified CRT pacing mode in response to detecting the atrial arrhythmia, the modified CRT pacing mode corresponding to a reduced total atrial blanking period;

administering the modified CRT pacing therapy; and

analyzing the sensed atrial depolarizations during the modified CRT pacing mode to confirm the presence of the detected atrial arrhythmia according to a second threshold for determination of the atrial arrhythmia, the second threshold higher than the first threshold.