Low frequency vibration assisted blood perfusion emergency system
First Claim
1. An emergency method of using a percussion device operable to emit non-invasive localized mechanical percussion at a frequency in the infrasonic to sonic range for enhancing intravenously administered thrombolytic drug action in clearance of an acute thrombotic arterial obstruction within a patient, comprising the steps of:
- a) applying non-invasive localized low frequency mechanical percussion at a frequency between 1 Hz-1000 Hz and a stroke length between 0.1-10 mm from said percussion device upon a targeted external body surface deemed proximate said acute thrombotic arterial obstruction, andb) intravenously administering a thrombolytic drug to said patient, prior to completion of step 260 (a),whereby said percussion device is placed in direct mechanical contact with said targeted external body surface, andwhereby said non-invasive localized low frequency mechanical percussion concurrently accelerates the action of said intravenously administered thrombolytic drug in the emergency clearance of said acute thrombotic arterial obstruction.
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Accused Products
Abstract
An emergency system for treatment of a patient (20) experiencing an acute vascular obstruction, employing a non-invasive vibrator (10), optimally in conjunction with drugs, for disrupting and lysing thromboses, relieving spasm (if associated), and thereby restoring blood perfusion. Vibrator (10) is operable in the sonic to infrasonic range, with a source output of up to 15 mm. For acute myocardial infarction cases, a pair of contacts (12), are advantageously placed to bridge the sternum at the fourth intercostal space. Vibration is initiated at 50 Hz (or any frequency, preferably within the 20-120 Hz range), and is ideally adjusted to a maximal amplitude (or force) deemed tolerable and safe to the patient (20), preferably with the administration of thrombolytic agents or other form of drug therapy. A synergistic effect is achieved between vibration and drugs to facilitate the disruption of thromboses, relieve spasm, and restore blood perfusion. In a variation, ultrasonic imaging may be used to direct vibration therapy.
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Citations
30 Claims
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1. An emergency method of using a percussion device operable to emit non-invasive localized mechanical percussion at a frequency in the infrasonic to sonic range for enhancing intravenously administered thrombolytic drug action in clearance of an acute thrombotic arterial obstruction within a patient, comprising the steps of:
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a) applying non-invasive localized low frequency mechanical percussion at a frequency between 1 Hz-1000 Hz and a stroke length between 0.1-10 mm from said percussion device upon a targeted external body surface deemed proximate said acute thrombotic arterial obstruction, and b) intravenously administering a thrombolytic drug to said patient, prior to completion of step 260 (a), whereby said percussion device is placed in direct mechanical contact with said targeted external body surface, and whereby said non-invasive localized low frequency mechanical percussion concurrently accelerates the action of said intravenously administered thrombolytic drug in the emergency clearance of said acute thrombotic arterial obstruction. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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- 11. A method of using a non-invasive vibrator administrable to emit vibration in the infrasonic to sonic frequency range to enhance the efficacy of a thrombolytic drug in the remediation of an acutely thrombosed artery, comprising the steps of intravenously administering said thrombolytic drug to a patient experiencing said acutely thrombosed artery, and applying non-invasive, transcutaenous localized mechanical vibration having a frequency of between 1 Hz to 1000 Hz and a displacement amplitude of between 0.1 mm to 10 mm via said vibrator placed in immediate contact upon a targeted external body surface deemed proximate said thrombosed artery in combination with said thrombolytic drug, in order to improve the effectiveness of said thrombolytic drug towards remediation of said thrombosed artery.
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19. An emergency method for enhancing fibrinolytic clot disruptive drug efficacy in the dissolution of a blood clot within an acutely thrombosed artery, comprising the steps of:
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a) intravenously administering a fibrinolytic drug to a patient deemed to be experiencing an acutely thrombosed artery, and b) applying non-invasive sonic vibration at a frequency of less than 1000 Hz and a stroke length in the range of 0.1 mm to 10 mm to said patient in combination with said fibrinolytic drug, whereby the source of said vibration is placed in immediate contact with said patient, and whereby said vibration assists the action of said fibrinolytic drug towards the dissolution of said blood clot within said acutely thrombosed artery. - View Dependent Claims (20, 21)
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- 22. An emergency method of using a non-invasive low frequency vibrator operable to emit vibration within the infrasonic to sonic frequency range to enhance the efficacy of a fibrinolytic drug in the restoration of blood flow of an acutely thrombosed coronary artery, comprising the steps of intravenously administering a fibrinolytic drug to a patient experiencing an acutely thrombosed coronary artery, and applying localized transthoracic vibration having a frequency less than 1000 Hz and a displacement amplitude in the range of 1 mm to 10 mm via said vibrator placed in direct mechanical contact upon a targeted external body surface overlying the thoracic cavity of said patient generally proximate the heart in combination with said fibrinolytic drug, in order to improve the effectiveness of said fibrinolytic drug towards the emergency restoration of blood flow of said acutely thrombosed coronary artery.
Specification