Implantable cell/tissue-based biosensing device
First Claim
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1. A biosensor device for sensing an analyte in a patient, the biosensor device comprising:
- a biosensing recognition element capable of interacting with the analyte and carrying out a response to electrical stimulation that is alterable upon interaction with the analyte;
an electrical interface contacting the biosensing recognition element;
stimulation circuitry, associated with the electrical interface, for delivering the electrical stimulation to the biosensing recognition element; and
sensing circuitry, associated with the electrical interface, for sensing the response of the biosensing recognition element to the electrical stimulation.
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Abstract
An implantable cell/tissue-based biosensor device detects and/or monitors the amount of one or more specific analytes within a patient. Stimulation circuitry stimulates the cells/tissue of the biosensor device causing the cells/tissue to evoke a response that is altered by the presence of a specific analyte. Sensing circuitry detects the evoked response and the amount of analyte is determined based on the detected response.
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Citations
20 Claims
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1. A biosensor device for sensing an analyte in a patient, the biosensor device comprising:
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a biosensing recognition element capable of interacting with the analyte and carrying out a response to electrical stimulation that is alterable upon interaction with the analyte; an electrical interface contacting the biosensing recognition element; stimulation circuitry, associated with the electrical interface, for delivering the electrical stimulation to the biosensing recognition element; and sensing circuitry, associated with the electrical interface, for sensing the response of the biosensing recognition element to the electrical stimulation. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
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10. An implantable biosensor device for sensing a plurality of analytes, the implantable biosensor device comprising:
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a plurality of biosensing recognition elements, each biosensing recognition element capable of interacting with at least one of the plurality of analytes and carrying out a response to electrical stimulation that is alterable upon interaction with at least one of the plurality of analytes; a plurality of electrical interfaces contacting the plurality of biosensing recognition elements; stimulation circuitry, associated with the plurality of electrical interfaces, for delivering the electrical stimulation to the plurality of biosensing recognition elements; and sensing circuitry, associated with the plurality of electrical interfaces, for sensing the response of the plurality of biosensing recognition elements to the electrical stimulation. - View Dependent Claims (11, 12, 13, 14, 15)
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16. A method of sensing an analyte in a patient, the method comprising:
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implanting a biosensing recognition element in the patient, the biosensing recognition element being capable of interacting with the analyte and carrying out a response to electrical stimulation that is alterable upon interaction with the analyte; electrically stimulating the biosensing recognition element; detecting the response of the biosensing recognition element to the electrical stimulation; and relating the detected response with an amount or presence of the analyte. - View Dependent Claims (17, 18, 19, 20)
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Specification