Dual-chamber pacemaker system for simultaneous bi-chamber pacing and sensing

• US 7,519,423 B2
• Filed: 08/29/2005
• Issued: 04/14/2009
• Est. Priority Date: 12/21/2001
• Status: Active Grant

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Van Oort, Geeske, Begemann, Malcolm J.
• Primary Examiner(s): Layno; Carl H
• Assistant Examiner(s): Gedeon; Brian T
• Application Number:
  US11/215,574
• Publication Number:
  US 20050288724A1
• Time in Patent Office: 1,324 Days
• Field of Search: 607/9, 607/17, 607/28
• US Class Current: 607/9
• CPC Class Codes: A61N 1/3622 comprising two or more electrodes co-operating with different heart regions
• CPC Class Codes: A61N 1/3684 for stimulating the heart at multiple sites of the ventricle or the atrium
• CPC Class Codes: A61N 1/36843 Bi-ventricular stimulation
• CPC Class Codes: A61N 1/3686 configured for selecting the electrode configuration on a lead A61N1/3688 takes precedence

Abstract

A method of pacing opposing chambers of a heart with a pacing system is provided. The pacing system comprises a first bipolar medical electrical lead having at least one first electrode configured for positioning in a first opposing chamber of the heart, a second bipolar medical electrical lead having at least one second electrode configured for positioning in a second opposing chamber of the heart, an implantable pulse generator operably connected to the first and second bipolar medical electrical leads. The implantable pulse generator further comprises a hermetically sealed housing capable of serving as a can electrode. The method designates a primary electrode configuration by selecting a cathode and an anode from either the first electrode, second electrode, or the can. Selection of the cathode is based on a comparison of thresholds measured in each chamber. Systems, programs and devices using the method are also provided.

Claims

1. A method of pacing opposing chambers of a heart with a pacing system, the pacing system comprising a first bipolar medical electrical lead having at least one first electrode configured for positioning in a first opposing chamber of the heart, a second bipolar medical electrical lead having at least one second electrode configured for positioning in a second opposing chamber of the heart, an implantable pulse generator operably connected to the first and second bipolar medical electrical leads, the implantable pulse generator further comprising an hermetically sealed housing capable of serving as a can electrode, and means for switching electrode configurations between the first electrode and the can electrode, between the second electrode and the can electrode, between the first electrode and the second electrode and between the second electrode and the first electrode, the method comprising:

determining a primary electrode configuration;

selecting a cathode from the first electrode, the second electrode and the can electrode based on the primary electrode configuration;

selecting an anode from the first electrode, the second electrode and the can electrode based on the primary electrode configuration;

delivering a first pulse between the cathode and the anode;

determining a first threshold of the first opposing chamber;

determining a second threshold of the second opposing chamber; and

selecting the first electrode as the cathode if the first threshold is higher than the second threshold.

2. The method of claim 1, further comprising:

determining an alternate electrode configuration;

selecting an alternate cathode from the first electrode, the second electrode and the can electrode based on the alternate electrode configuration;

selecting an alternate anode from the first electrode, the second electrode and the can electrode based on the alternate electrode configuration; and

delivering a second pulse between the alternate cathode and the alternate anode.

3. The method of claim 2, further comprising:

re-selecting the cathode and the anode;

delivering a third pulse between the cathode and the anode;

re-selecting the alternate cathode and the alternate anode; and

delivering a fourth pulse between the alternate cathode and the alternate anode.

4. The method of claim 1, further comprising:

delivering the first pulse between the cathode and the anode so that the direction of the pulse occurs from the first opposing chamber to the second opposing chamber.

5. The method of claim 1, further comprising:

delivering the first pulse between the cathode and the anode so tat the direction of the pulse occurs from the second opposing chamber to the first opposing chamber.

6. The method of claim 1, further comprising:

delivering the first pulse between the cathode and the anode in a first direction; and

delivering at least one subsequent pulse between the cathode and the anode in the first direction.

7. The method of claim 1, further comprising:

delivering the first pulse from the cathode; and

simultaneously delivering a second pulse from the anode.

8. The method of claim 1, further comprising sensing a signal from the heart via at least one of the first electrode and the second electrode.

9. A computer usable medium including a program for opposing chambers of a heart with a pacing system, the pacing system comprising a first unipolar medical electrical lead having at least one first electrode configured for positioning in a first opposing chamber of the heart, a second unipolar medical electrical lead having at least one second electrode configured for positioning in a second opposing chamber of the heart, an implantable pulse generator operably connected to the first and second unipolar medical electrical leads, the implantable pulse generator further comprising an hermetically sealed housing capable of serving as a can electrode, and means for switching electrode configurations between the first electrode and the can electrode, between the second electrode and the can electrode, between the first electrode and the second electrode and between the second electrode and the first electrode, the program comprising:

computer program code that determines a primary electrode configuration;

computer program code that selects a cathode from the first electrode, the second electrode and the can electrode based on the primary electrode configuration;

computer program code that selects an anode from the first electrode, the second electrode arid the can electrode based on the primary electrode configuration;

computer program code that delivers a first pulse between the cathode and the anode;

computer program code that determines a first threshold of the first opposing chamber;

computer program code that determines a second threshold of the second opposing chamber; and

computer program code that selects the first electrode as the cathode if the first threshold is higher than the second threshold.

10. The program of claim 9, further comprising:

computer program code that determines an alternate electrode configuration;

computer program code that selects an alternate cathode from the first electrode, the second electrode and the can electrode based on the alternate electrode configuration;

computer program code that selects an alternate anode from the first electrode, the second electrode and the can electrode based on the alternate electrode configuration; and

computer program code that delivers a second pulse between the alternate cathode and the alternate anode.

11. The program of claim 10, further comprising:

computer program code that re-selects the cathode and the anode;

computer program code that delivers a third pulse between the cathode and the anode;

computer program code that re-selects the alternate cathode and the alternate anode; and

computer program code that delivers a fourth pulse between the alternate cathode and the alternate anode.

12. The program of claim 9, further comprising:

computer program code that delivers the first pulse between the cathode and the anode so that the direction of the pulse occurs from the first opposing chamber to the second opposing chamber.

13. The program of claim 9, further comprising:

computer program code that delivers the first pulse between the cathode and the anode so that the direction of the pulse occurs from the second opposing chamber to the first opposing chamber.

14. The program of claim 9, further comprising:

computer program code that delivers the first pulse between the cathode and the anode in a first direction; and

computer program code that delivers at least one subsequent pulse between the cathode and the anode in the first direction.

15. The program of claim 9, further comprising:

computer program code that delivers the first pulse from the cathode; and

computer program code that simultaneously delivering a second pulse from the anode.

16. A computer usable medium including a program for opposing chambers of a heart with a pacing system, the pacing system comprising a first bipolar medical electrical lead having at least one first electrode configured for positioning in a first opposing chamber of the heart, a second bipolar medical electrical lead having at least one second electrode configured for positioning in a second opposing chamber of the heart, an implantable pulse generator operably connected to the first and second bipolar medical electrical leads, the implantable pulse generator further comprising an hermetically sealed housing capable of serving as a can electrode, and means for switching electrode configurations between the first electrode and the can electrode, between the second electrode and the can electrode, between the first electrode and the second electrode and between the second electrode and the first electrode, the program comprising:

computer program code that determines a primary electrode configuration;

computer program code that selects a cathode from the first electrode, the second electrode and the can electrode based on the primary electrode configuration;

computer program code that selects an anode from the first electrode, the second electrode and the can electrode based on the primary electrode configuration;

computer program code that delivers a first pulse between the cathode and the anode;

computer program code that determines a first threshold of the first opposing chamber;

computer program code that determines a second threshold of the second opposing chamber; and

computer program code that selects the first electrode as the cathode if the first threshold is higher than the second threshold.