Assay test strips and reading same
First Claim
1. An assay test strip, comprising:
- a flow path for a fluid sample;
a sample receiving zone coupled to the flow path;
a label that specifically binds a target analyte;
a detection zone coupled to the flow path and comprising a region of interest and an immobilized test reagent that specifically binds the target analyte; and
at least one position marker aligned with respect to the region of interest such that location of the at least one position marker indicates a position of the region of interest, wherein the at least one position marker is calibrated to provide at least one reference optical response to illuminating light within a specified wavelength range.
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Accused Products
Abstract
An assay test strip includes a flow path, a sample receiving zone, a label, a detection zone that includes a region of interest, and at least one position marker. The at least one position marker is aligned with respect to the region of interest such that location of the at least one position marker indicates a position of the region of interest. A diagnostic test system includes a reader that obtains light intensity measurement from exposed regions of the test strip, and a data analyzer that performs at least one of (a) identifying ones of the light intensity measurements obtained from the test region based on at least one measurement obtained from the at least one reference feature, and (b) generating a control signal modifying at least one operational parameter of the reader based on at least one measurement obtained from the at least one reference feature.
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Citations
27 Claims
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1. An assay test strip, comprising:
- a flow path for a fluid sample;
a sample receiving zone coupled to the flow path;
a label that specifically binds a target analyte;
a detection zone coupled to the flow path and comprising a region of interest and an immobilized test reagent that specifically binds the target analyte; and
at least one position marker aligned with respect to the region of interest such that location of the at least one position marker indicates a position of the region of interest, wherein the at least one position marker is calibrated to provide at least one reference optical response to illuminating light within a specified wavelength range. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27)
- a flow path for a fluid sample;
Specification