Particle beam irradiation method and particle beam irradiation apparatus used for the same

• US 7,525,104 B2
• Filed: 02/04/2005
• Issued: 04/28/2009
• Est. Priority Date: 02/04/2005
• Status: Active Grant

• Current Assignee: Mitsubishi Denki Kabushiki Kaisha (Mitsubishi Electric Corporation)
• Original Assignee: Mitsubishi Denki Kabushiki Kaisha (Mitsubishi Electric Corporation)
• Inventors: Harada, Hisashi
• Primary Examiner(s): Souw; Bernard E
• Application Number:
  US11/596,707
• Publication Number:
  US 20080067401A1
• Time in Patent Office: 1,544 Days
• Field of Search: 250/396.R, 250/398, 250/491.1, 250/492.1, 250/492.3, 250/505.1, 250/503.1, 378/65, 378/137, 378/156, 378/158, 378/159
• US Class Current: 250/396.00R
• CPC Class Codes: A61N 2005/1087 Ions; Protons
• CPC Class Codes: A61N 2005/1096 Elements inserted into the radiation path placed on the patient, e.g. bags, bolus, compensators
• CPC Class Codes: A61N 5/10 X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy A61N5/01 takes precedence
• CPC Class Codes: A61N 5/1043 Scanning the radiation beam, e.g. spot scanning or raster scanning
• CPC Class Codes: G21K 5/04 with beam-forming means

Abstract

In a particle beam irradiation method and a particle beam irradiation apparatus in which depth direction irradiation field spread and lateral direction irradiation field spread are performed, an irradiation dose in each of irradiation layers of an irradiation target is made substantially constant, and control is simplified.

The depth direction irradiation field spread is made the active irradiation field spread in which plural irradiation layers having different ranges in an irradiation direction of the particle beam are superimposed, the lateral direction irradiation field spread is made the active irradiation field spread in which irradiation spots of the particle beam are superimposed in the lateral direction, and a bolus having a shape along a deepest part of the irradiation target in the depth direction is disposed to cross the particle beam.

Claims

1. A particle beam irradiation method which uses both a depth direction irradiation field spread for spreading an irradiation field of a particle beam in a depth direction along an irradiation direction of the particle beam, and a lateral direction irradiation field spread for spreading the irradiation field of the particle beam in a lateral direction perpendicular to the irradiation direction of the particle beam, and which irradiates the particle beam on an irradiation target, wherein

the depth direction irradiation field spread is an active irradiation field spread in which plural irradiation layers having different ranges in the irradiation direction of the particle beam are superimposed,

the lateral direction irradiation field spread is an active irradiation spread in which irradiation spots of the particle beam are superimposed in the lateral direction, and

a bolus having a shape along a deepest part of the irradiation target in the depth direction is disposed to cross the particle beam.

2. The particle beam irradiation method according to claim 1, wherein at least one irradiation layer selected from the plural irradiation layers is re-irradiated once or more with the particle beam.

3. The particle beam irradiation method according to claim 2, wherein the selected irradiation layer is made an irradiation layer having a highest irradiation dose in the plural irradiation layers, and the selected irradiation layer is re-irradiated once or more with the particle beam.

4. The particle beam irradiation method according to claim 2, wherein plural selected irradiation layers are selected from the plural irradiation layers, and each of the plural selected irradiation layers is re-irradiated once or more with the particle beam.

5. The particle beam irradiation method according to claim 4, wherein the number of times of reirradiation of each of the plural selected irradiation layers corresponds to a planned irradiation dose for each of the selected irradiation layers.

6. The particle beam irradiation method according to claim 1, wherein a displacement of the irradiation target is detected, and turning on/off of irradiation of the particle beam is performed according to the displacement of the irradiation target.

7. The particle beam irradiation method according to claim 1, wherein a displacement of the irradiation target is detected, and an irradiation dose of the particle beam is controlled according to the displacement of the irradiation target.

8. The particle beam irradiation method according to claim 1, wherein in a case where the irradiation target is displaced mainly along a specified direction, the particle beam is irradiated to the irradiation target from a direction oblique to the specified direction.

9. A particle beam irradiation apparatus comprising:

a particle beam generation part for generating a particle beam;

a particle beam transport part for transporting the particle beam generated by the particle beam generation part;

a particle beam irradiation part for irradiating the particle beam transported by the particle beam transport part to an irradiation target;

depth direction irradiation field spread means for spreading an irradiation field of the particle beam in a depth direction along an irradiation direction of an irradiation direction of the particle beam; and

lateral direction irradiation field spread means for spreading the irradiation field of the particle beam in a lateral direction perpendicular to the irradiation direction of the particle beam, wherein

the depth direction irradiation field spread means is an active depth direction irradiation field spread means for superimposing plural irradiation layers having different ranges in the irradiation direction of the particle beam,

the lateral direction irradiation field spread means is an active irradiation field spread means for superimposing irradiation spots of the particle beam in the lateral direction, and

a bolus having a shape along a deepest part of the irradiation target in the depth direction is disposed to cross the particle beam.

10. The particle beam irradiation apparatus according to claim 9, wherein the active depth direction irradiation field spread means is coupled to an accelerator for accelerating the particle beam, and changes its acceleration energy.

11. The particle beam irradiation apparatus according to claim 9, wherein the active depth direction irradiation field spread means is a range shifter disposed to cross the particle beam, and the range shifter adjusts energy of the particle beam according to a given adjustment signal.

12. The particle beam irradiation apparatus according to claim 9, wherein the particle beam irradiation apparatus further comprises displacement detection means for detecting a displacement of the irradiation target, and turning on/off means for turning on/off irradiation of the particle beam, and the particle beam is turned on/off according to the displacement of the irradiation target.

13. The particle beam irradiation apparatus according to claim 9, wherein the particle beam irradiation apparatus further comprises displacement detection means for detecting a displacement of the irradiation target, and adjustment means for adjusting an irradiation dose of the particle beam, and the irradiation dose of the particle beam is adjusted according to the displacement of the irradiation target.

14. The particle beam irradiation apparatus according to claim 9, wherein the particle beam irradiation part includes an irradiation nozzle for irradiating the particle beam, the irradiation nozzle is mounted on a rotation gantry, and in a case where the irradiation target is displaced mainly along a specified direction, the particle beam is irradiated to the irradiation target from a direction oblique to the specified direction.