Apparatus and method for controlling fraction of inspired oxygen

• US 7,527,054 B2
• Filed: 05/24/2005
• Issued: 05/05/2009
• Est. Priority Date: 05/24/2005
• Status: Expired due to Fees

• Current Assignee: General Electric Company
• Original Assignee: General Electric Company
• Inventors: Misholi, Boaz
• Primary Examiner(s): Yu; Justine R
• Assistant Examiner(s): DIXON, ANNETTE FREDRICKA
• Application Number:
  US11/136,087
• Publication Number:
  US 20060266355A1
• Time in Patent Office: 1,442 Days
• Field of Search: 128/200.24, 128/203.12, 128/203.13, 128/203.14, 128/203.16, 128/203.17, 128/204.18, 128/204.21, 128/204.23, 128/204.22, 128/205.11, 128/203.25, 128/203.26, 128/203.27
• US Class Current: 128/204.22
• CPC Class Codes: A61B 5/1455 using optical sensors, e.g. spectral photometrical oximeters
• CPC Class Codes: A61M 16/0051 with alarm devices
• CPC Class Codes: A61M 16/024 including calculation means, e.g. using a processor
• CPC Class Codes: A61M 16/12 by mixing different gases
• CPC Class Codes: A61M 2202/0208 Oxygen
• CPC Class Codes: A61M 2230/005 Parameter used as control input for the apparatus
• CPC Class Codes: A61M 2230/205 partial oxygen pressure (P-O2)

Abstract

A method and apparatus for operating a ventilator to control the fraction of pressure inspired oxygen (FiO₂) to a patient that includes: providing a ventilator controller that includes a software algorithm, a pulse oximeter and a FiO₂ flow rate controller; measuring the pulse oximetry of the patient and computing an average pulse oximetry value over a time period; selecting a first, second and third pulse oximetry levels as set points for the ventilator controller; selecting an update time interval; decreasing the FiO₂ flow rate by a first incremental amount when the average pulse oximetry value is greater than the first level; increasing the FiO₂ flow rate by a second incremental amount when the average pulse oximetry value is less than the second level; increasing the FiO₂ flow rate to the maximum and initiating an alarm condition when the average pulse oximetry value is less than the third level.

Claims

1. A method of operating a ventilator to control the fraction of pressure inspired oxygen (FiO₂), the method comprising:

providing a pulse oximeter to measure a patient'"'"'s pulse oximetry;

providing a FiO₂ flow rate controller, wherein the flow rate controller controls the flow rate of FiO₂ to the patient;

measuring the patient'"'"'s pulse oximetry and providing a measured pulse oximetry value;

averaging the patient'"'"'s measured pulse oximetry value over a period of time;

providing a ventilator controller responsive to the average of the patient'"'"'s measured pulse oximetry value, wherein the FiO₂ flow rate controller is responsive to the ventilator controller and controls the flow rate of FiO₂ to the patient;

selecting the time period for averaging the patient'"'"'s measured pulse oximetry value;

selecting a first, a second, and a third pulse oximetry level as set points for the ventilator controller;

selecting an FiO₂ operating range having a low end, a high end and a mid-point, wherein the midpoint of the range is equal to one-half the sum of the low end and the high end;

selecting a first incremental amount for decreasing the flow rate of FiO₂ and a second incremental amount for increasing the flow rate of FiO₂;

selecting an update time interval, wherein the update time interval is the interval of time between comparisons by the ventilator controller of the set points and the averaged measured pulse oximetry value of the patient;

setting the FiO₂ flow rate controller at a flow rate equal to the mid-point of the operating range;

decreasing the flow rate of FiO₂ by the first incremental amount when the average pulse oximetry value is greater than the first level;

increasing the flow rate of FiO₂ by the second incremental amount when the average pulse oximetry value is less than the second level; and

increasing the flow rate of FiO₂ to a maximum rate when the average pulse oximetry value is less than the third level.

2. The method of operating a ventilator according to claim 1, wherein the method further comprises maintaining the flow rate of FiO₂ at the maximum when the average pulse oximetry value is less than the third level and initiating an alarm condition.

3. The method of operating a ventilator according to claim 2, wherein the method further comprises manually resetting the alarm.

4. The method of operating a ventilator according to claim 3, wherein the period of time is about 10 seconds before the update time interval.

5. The method of operating a ventilator according to claim 1, wherein the period of time is from 5 to 60 seconds before the end of the update time interval.

6. The method of operating a ventilator according to claim 1, wherein the ventilator controller includes software which automatically adjusts the flow rate of FiO₂ based upon the average pulse oximetry value of the patient.

7. The method of operating a ventilator according to claim 1, wherein the update time interval is at least 30 seconds.

8. The method of operating a ventilator according to claim 1, wherein the ventilator controller includes a normal operating mode for the control of the flow rate of FiO₂.

9. The method of operating a ventilator according to claim 1, wherein the flow rate of FiO₂ does not change when the average pulse oximetry value is between the first level and the second level.

10. The method of operating a ventilator according to claim 1, wherein the alarm condition actuates an audible alarm signal, a visual alarm signal or both an audible alarm signal and a visual alarm signal.

11. The method of operating a ventilator according to claim 1, wherein the pulse oximetry is measured using a probe attached to the patient'"'"'s finger, toe or ear lobe.

12. The method of operating a ventilator according to claim 1, wherein FiO₂ operating range is between about 40% and 100%.

13. The method of operating a ventilator according to claim 1, wherein FiO₂ operating range is between about 60% and 90%.

14. A method of operating a ventilator to control the fraction of pressure inspired oxygen (FiO₂), the method comprising:

providing a pulse oximeter to measure a patient'"'"'s pulse oximetry;

providing a FiO₂ flow rate controller, wherein the flow rate controller controls the flow rate of FiO₂ to the patient;

measuring the patient'"'"'s pulse oximetry and providing a measured pulse oximetry value;

averaging the patient'"'"'s measured pulse oximetry value over a period of time;

providing a ventilator controller responsive to the average of the patient'"'"'s measured pulse oximetry value, wherein the FiO₂ flow rate controller is responsive to the ventilator controller and controls the flow rate of FiO₂ to the patient;

selecting the time period for averaging the patient'"'"'s measured pulse oximetry value;

selecting a first, a second, and a third pulse oximetry level as set points for the ventilator controller;

selecting an FiO₂ operating range having a low end, a high end and a mid-point, wherein the midpoint of the range is equal to one-half the sum of the low end and the high end;

selecting a first incremental amount for decreasing the flow rate of FiO₂ and a second incremental amount for increasing the flow rate of FiO₂;

selecting an update time interval, wherein the update time interval is the interval of time between comparisons by the ventilator controller of the set points and the averaged measured pulse oximetry value of the patient;

setting the FiO₂ flow rate controller at a flow rate equal to the mid-point of the operating range;

decreasing the flow rate of FiO₂ by the first incremental amount when the average pulse oximetry value is greater than the first level;

increasing the flow rate of FiO₂ by the second incremental amount when the average pulse oximetry value is less than the second level;

increasing the flow rate of FiO₂ to a maximum rate and initiating an alarm condition when the average pulse oximetry value is less than the third level;

maintaining the flow rate of FiO₂ at the maximum after an alarm condition is initiated; and

resetting the alarm condition when the average pulse oximetry value increases above the third level.

15. The method of operating a ventilator according to claim 14, wherein the update time interval is at least 30 seconds.

16. The method of operating a ventilator according to claim 14, wherein the algorithm comprises a normal operating mode for the control of the flow rate of FiO₂.

17. The method of operating a ventilator according to claim 14, wherein the flow rate of FiO₂ does not change when the average pulse oximetry value is between the first level and the second level.

18. The method of operating a ventilator according to claim 14, wherein the update time is automatically set to less than 1 minute when the alarm condition is initiated.

19. The method of operating a ventilator according to claim 14, wherein the alarm condition actuates an audible alarm signal, a visual alarm signal or both an audible alarm signal and a visual alarm signal.

20. The method of operating a ventilator according to claim 14, wherein the pulse oximetry is measured using a probe attached to the patient'"'"'s finger, toe or ear lobe.

21. A method of operating a ventilator to control the fraction of pressure inspired oxygen (FiO₂), the method comprising:

providing a pulse oximeter to measure a patient'"'"'s pulse oximetry;

providing a FiO₂ flow rate controller, wherein the flow rate controller controls the flow rate of FiO₂ to the patient;

measuring the patient'"'"'s pulse oximetry and providing a measured pulse oximetry value;

averaging the patient'"'"'s measured pulse oximetry value over a period of time;

providing a ventilator controller responsive to the average of the patient'"'"'s measured pulse oximetry value, wherein the FiO₂ flow rate controller is responsive to the ventilator controller and controls the flow rate of FiO₂ to the patient;

selecting a first, a second, and a third pulse oximetry level as set points for the ventilator controller, wherein the flow rate of FiO₂ does not change when the pulse oximetry is between the first level and the second level;

selecting an FiO₂ operating range having a low end, a high end and a mid-point, wherein the midpoint of the range is equal to one-half the sum of the low end and high end;

selecting a first incremental amount for decreasing the flow rate of FiO₂ and a second incremental amount for increasing the flow rate of FiO₂;

selecting an update time interval, wherein the update time interval is the interval of time between comparisons by the ventilator controller of the set points and the measured pulse oximetry of the patient and wherein the update time is at least 30 seconds;

setting the FiO₂ flow rate controller at a flow rate equal to the mid-point of the operating range;

decreasing the flow rate of FiO₂ by the first incremental amount when the average pulse oximetry value is greater than the first level and the flow rate is greater than or equal to the low end of the FiO₂ operating range;

increasing the flow rate of FiO₂ by the second incremental amount when the average pulse oximetry value is less than the second level and the flow rate is less than or equal to the high end of the FiO₂ operating range;

increasing the flow rate of FiO₂ to a maximum rate and initiating an alarm condition when the average pulse oximetry value is less than the third level, wherein the update time is automatically set to less than 1 minute when the alarm condition is initiated;

maintaining the flow rate of FiO₂ at the maximum after an alarm condition is initiated; and

resetting the alarm condition when the average pulse oximetry value increases above the third level.

22. A ventilator system for controlling the fraction of pressure inspired oxygen (FiO₂) in air delivered to a patient, the ventilator system comprising:

a pulse oximeter which measures the pulse oximetry of a patient and generates an output signal in response thereto;

a ventilator controller comprising a keypad, a display and a software algorithm, wherein the keypad and display are adapted to enter an update time interval, a first, second, and third pulse oximetry level set points, a FiO₂ flow rate range, a first incremental amount for decreasing the flow rate of FiO₂ and a second incremental amount for increasing the flow rate of FiO₂; and

a time period over which the patient'"'"'s measured pulse oximetry value is averaged;

a FiO₂ flow rate controller responsive to the ventilator controller; and

a face mask, nasal mask or endotracheal tube for delivering the air to the patient, wherein the ventilator controller software algorithm computes an average pulse oximetry value and, at the end of the update time interval, compares the average pulse oximetry value to the first, second and third pulse oximeter level set points, the ventilator controller automatically controlling the flow rate of FiO₂ to the patient such that the flow rate of FiO₂ decreases by a first incremental amount when the average pulse oximetry value is greater than the first level, increases the flow rate of FiO₂ by a second incremental amount when the average pulse oximetry value is less than the second level, and increases the flow rate of FiO₂ to a maximum rate when the average pulse oximetry value is less than the third level.

23. The ventilator system as set forth in claim 22, wherein the update time interval is the interval of time between comparisons by the ventilator controller software algorithm of the set points and the output signal of the pulse oximeter.

24. The ventilator system as set forth in claim 22, wherein the flow rate controller comprises a control valve.