Implantable drug delivery device

• US 7,527,621 B2
• Filed: 08/16/2006
• Issued: 05/05/2009
• Est. Priority Date: 02/13/2001
• Status: Expired due to Fees

• Current Assignee: Second Sight Medical Products, Inc.
• Original Assignee: Second Sight Medical Products, Inc.
• Inventors: Greenberg, Robert
• Primary Examiner(s): Lucchesi; Nicholas D
• Assistant Examiner(s): Price; Nathan R
• Application Number:
  US11/505,695
• Publication Number:
  US 20070026048A1
• Time in Patent Office: 993 Days
• Field of Search: 604/289, 604294-302, 604/521, 6048901-8921, 60428801-28804
• US Class Current: 604/890.1
• CPC Class Codes: A61F 9/0017 implantable in, or in contact with, the eye, e.g. ocular inserts
• CPC Class Codes: A61N 1/0543 Retinal electrodes

Abstract

The invention is directed to an implantable device to enable delivery of drugs to the retina. The device minimizes stress to the retina by virtue of its softness and smooth shape that conform to the retina. Drugs are delivered by osmosis or by the device dissolving. It may be connected to an externally mounted pump and drug reservoir that control the amount of drug. It contains one or more holes that are positioned to deliver drugs to the desired location. Drugs may stimulate the retina to enable vision in blind patients. Drugs may be injected directly inside the eye by a trans-scleral pump and valve drug delivery device.

Claims

1. An implantable device for drug delivery comprising:

a biologically inert hollow body defining at least one void;

said void containing at least one drug;

said hollow body having a generally oval shape;

said oval shaped body being curved such that it substantially conforms to the spherical curvature of at least a portion of a recipient'"'"'s eye,

said oval shape being optimized to minimize physical stress on the retina;

said inert body further comprising at least one mounting aperture suitable for attaching said inert body to a retina with a tack and

said inert body further comprising a strain relief tab which is thinner than the rest of said inert body, defined by a strain relief slot partially around said mounting aperture.

2. The implantable device for drug delivery according to claim 1, wherein said drug delivery is comprised of osmotic release.

3. The implantable device for drug delivery according to claim 1, wherein said generally oval shape is generally circular.

4. The implantable device for drug delivery according to claim 1, wherein said inert body is comprised of an oval shape having a radius of spherical curvature that approximates the curvature of the eye, that is decreasing near the edge of said inert body, thus causing the edge of said inert body to lift off of the retina, eliminating stress concentrations in the retina from contact with said inert body.

5. The implantable device for drug delivery according to claim 1, wherein said inert body is attached to a grasping handle that is suitable for holding with a surgical instrument during implantation.

6. The implantable device for drug delivery according to claim 1, wherein the drug delivery is neurotrophic factor.