Integrated automatic blood processing unit
First Claim
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1. A system for deglycerolizing red blood cells (“
- RBCs”
), comprising;
a recirculation bag; and
a continuous flow centrifuge (“
CFC”
) to separate a waste product from fluid containing RBCs, said CFC in fluid communication with said recirculation bag by a first tubing segment, said first tubing segment terminating at its first end at said CFC, and terminating at its second end at said recirculation bag;
a blood pump to pump fluid containing RBCs from said recirculation bag to said CFC, said blood pump configured on said first tubing segment;
a first valve to control the flow of fluid into said recirculation bag, said first valve configured on a second tubing segment, said second tubing segment terminating at its first end at said CFC, and terminating at its second end at said recirculation bag;
a deglycerolized RBC bag to contain deglycerolized RBCs, said deglycerolized RBC bag in fluid communication with said second tubing segment by a third tubing segment, said third tubing segment terminating at its first end at said deglycerolized RBC bag, and terminating at its second end at a first junction with said second tubing segment, said first junction configured on said second tubing segment between said CFC and said first valve;
a second valve to control the flow of fluid into said deglycerolized RBC bag, said second valve configured on said third tubing segment; and
a cassette through which said first, second and third tubing segments pass.
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Accused Products
Abstract
A system for automatically processing blood components is described. The system includes a console, which contains all motors, pumps, sensors, valves and control circuitry, and a unique disposable set that includes a cassette supporting a centrifuge with an improved design, pump interfaces with an improved design, component and solution bags, and tubing. Various processes are implemented using a specific disposable set for each process which allows automatic identification of the process to be performed the console.
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Citations
17 Claims
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1. A system for deglycerolizing red blood cells (“
- RBCs”
), comprising;a recirculation bag; and a continuous flow centrifuge (“
CFC”
) to separate a waste product from fluid containing RBCs, said CFC in fluid communication with said recirculation bag by a first tubing segment, said first tubing segment terminating at its first end at said CFC, and terminating at its second end at said recirculation bag;a blood pump to pump fluid containing RBCs from said recirculation bag to said CFC, said blood pump configured on said first tubing segment; a first valve to control the flow of fluid into said recirculation bag, said first valve configured on a second tubing segment, said second tubing segment terminating at its first end at said CFC, and terminating at its second end at said recirculation bag; a deglycerolized RBC bag to contain deglycerolized RBCs, said deglycerolized RBC bag in fluid communication with said second tubing segment by a third tubing segment, said third tubing segment terminating at its first end at said deglycerolized RBC bag, and terminating at its second end at a first junction with said second tubing segment, said first junction configured on said second tubing segment between said CFC and said first valve; a second valve to control the flow of fluid into said deglycerolized RBC bag, said second valve configured on said third tubing segment; and a cassette through which said first, second and third tubing segments pass. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16)
- RBCs”
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17. A method of deglycerolizing red blood cells (“
- RBCs”
), comprising;providing a RBC deglycerolizing system, including a continuous flow centrifuge (“
CFC”
) adapted to separate deglycerolized RBCs from a waste product,a glycerolized RBC bag containing thawed, glycerolized RBCs, at least two solution bags containing at least one solution, a recirculation bag, said recirculation bag in fluid communication with said glycerolized RBC bag, said at least two solution bags, said CFC and a deglycerolized RBC bag by way of tubing, and a cassette through which said tubing passes; configuring said deglycerolizing system with a console including electronic and mechanical components to operate said deglycerolizing system; and operating said deglycerolizing system to deglycerolize RBCs.
- RBCs”
Specification