Cardiac rhythm management systems and methods using multiple morphology templates for discriminating between rhythms

• US 7,539,536 B2
• Filed: 03/21/2006
• Issued: 05/26/2009
• Est. Priority Date: 11/08/2002
• Status: Active Grant

• Current Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Original Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Inventors: Schwartz, Mark, Kim, Jaeho, Bocek, Joseph M.
• Primary Examiner(s): Layno; Carl H
• Assistant Examiner(s): Behringer; Luther G
• Application Number:
  US11/277,095
• Publication Number:
  US 20060155201A1
• Time in Patent Office: 1,162 Days
• Field of Search: 600/508, 600/509, 600515-518, 600/510, 607/4, 607/5, 607/9, 607/14, 607/28
• US Class Current: 600/518
• CPC Class Codes: A61B 5/35 by template matching
• CPC Class Codes: A61N 1/3956 Implantable devices for applying electric shocks to the heart, e.g. for cardioversion

Abstract

This document describes systems, devices, and methods that use multiple morphology templates for discriminating between rhythms, such as supraventricular tachyarrhythmias (SVTs) and ventricular tachyarrhythmias (VTs), for delivering a countershock in response to a VT episode, but withholding delivery of such a countershock in response to an SVT episode. In certain examples, the particular morphology used for storing morphological features is selected at least in part using a sensor-indicated activity level of a subject, or a metabolic need of the subject.

Claims

1. A machine-readable medium including instructions that, when performed by a machine, cause the machine to:

obtain a first reference morphological template from a subject'"'"'s heart in the absence of an arrhythmia, while the subject is resting or inactive;

obtain a second reference morphological template from the heart under a condition different from that of the first morphological template;

obtain at least one current cardiac complex;

determine a degree of correlation between the at least one cardiac complex and at least one of the first and second morphological templates; and

declare one of first and second rhythm states at least in part using the determined degree of correlation.

2. The machine-readable medium of claim 1, further including instructions that cause the machine to determine whether to deliver or inhibit a shock to a heart at least in part using which of the first and second rhythm states was declared.

3. The machine-readable medium of claim 1, in which the instructions to obtain the second morphological template occur under a condition in which the subject manifests at least one activity indicator value that is higher than the at least one activity indicator value that occurred during the obtaining the first morphological template.

4. The machine-readable medium of claim 1, in which the instructions to obtain the second morphological template occur under a condition in which the subject manifests an arrhythmia.

5. The machine-readable medium of claim 4, in which the instructions to obtain the second morphological template occur under a condition in which the subject manifests an induced arrhythmia.

6. The machine-readable medium of claim 1, in which the instructions to obtain the second morphological template occur during high-rate atrial pacing.

7. The machine-readable medium of claim 1, in which the instructions to obtain the second morphological template occur during controlled physical exertion.

8. The machine-readable medium of claim 1, in which the instructions to obtain the second morphological template occur under a condition in which the subject manifests a supraventricular tachyarrhythmia.

9. The machine-readable medium of claim 1, further comprising instructions to recurrently update at least one of the first and second morphological templates.

10. The machine-readable medium of claim 8, in which the episode of the supraventricular tachyarrhythmia is obtained from historical electrogram data.

11. A method comprising:

obtaining a first reference morphological template from a subject'"'"'s heart in the absence of an arrhythmia, while the subject is resting or inactive;

obtaining a second reference morphological template from the heart during high-rate atrial pacing;

obtaining at least one current cardiac complex;

determining a degree of correlation between the at least one cardiac complex and at least one of the first and second morphological templates; and

declaring one of a first and second rhythm state at least in part using the determined degree of correlation.

12. The method of claim 11, further including determining whether to deliver or inhibit a shock to a heart at least in part using which of the first and second rhythm states was declared.

13. A method comprising:

obtaining a first reference morphological template from a subject'"'"'s heart in the absence of an arrhythmia, while the subject is resting or inactive;

obtaining a second reference morphological template from the heart during exercise;

obtaining at least one current cardiac complex;

determining a degree of correlation between the at least one cardiac complex and at least one of the first and second morphological templates; and

declaring one of a first and second rhythm state at least in part using the determined degree of correlation.

14. The method of claim 13, further including determining whether to deliver or inhibit a shock to a heart at least in part using which of the first and second rhythm states was declared.

15. A method comprising:

obtaining a first reference morphological template from a subject'"'"'s heart in the absence of an arrhythmia, while the subject is resting or inactive;

obtaining a second reference morphological template, in which the second template is obtained from historical electrogram data of an episode of supraventricular tachyarrhythmia;

obtaining at least one current cardiac complex;

determining a degree of correlation between the at least one cardiac complex and at least one of the first and second morphological templates; and

declaring one of a first and second rhythm state at least in part using the determined degree of correlation.

16. The method of claim 15, further including determining whether to deliver or inhibit a shock to a heart at least in part using which of the first and second rhythm states was declared.

17. A system comprising:

an electrogram sensing circuit, configured to receive first and second intrinsic cardiac signals, the electrogram sensing circuit configured to provide cardiac complexes, each cardiac complex having a morphology, and an indication of heart rate obtained from the first intrinsic cardiac signal;

a sensor, including a sensor output indicative of activity or metabolic need of the subject;

a stored first reference morphological template, coupled to the electrogram sensing circuit, the stored first morphological template obtained from the heart in the absence of an arrhythmia while the subject is resting or inactive;

a stored second reference morphological template, coupled to the electrogram sensing circuit and the sensor, the stored second morphological template obtained from the heart under a different sensor output condition from that of the first morphological template;

a correlation module, coupled to the electrogram sensing circuit and the first and second morphological templates, the correlation module configured to declare an indication of one of a first and a second rhythm state, including discriminating between the first and second rhythm states using a comparison of a morphology of at least one current cardiac complex of the second intrinsic cardiac signal to at least one of the first and second morphological templates, the at least one of the first and second morphological templates selected using the indication of heart rate provided by the electrogram sensing circuit; and

a template updating control module, coupled to the second morphological template and the correlation module, the template updating control module configured to provide an updated exercise template to the correlation module if;

(a) a first exercise template is not available to the correlation module or (b) an available exercise template is insufficiently correlated to the at least one cardiac complex of the intrinsic cardiac signal.

18. The system of claim 17, further comprising:

a shock circuit, configured to be coupled to at least one electrode for delivering a shock to the heart; and

a shock control module, coupled to the correlation module and the shock circuit, the shock control module configured to trigger a shock if the correlation module declares the indication of the second rhythm state, and the shock control module configured to inhibit a shock if the correlation module declares the indication of the first rhythm state.

19. The system of claim 17, further comprising:

a first electrode, sized and shaped for being implanted in or near a subject'"'"'s heart, the first electrode configured for sensing a heart rate from cardiac complexes;

a second electrode, sized and shaped for being implanted in or near the heart, the second electrode configured for sensing a morphology of a cardiac complex.

20. A method comprising:

obtaining a first reference morphological template from a subject'"'"'s heart in the absence of an arrhythmia, while the subject is resting or inactive;

obtaining a second reference morphological template from the heart under a condition different from that of the first morphological template;

obtaining at least one current cardiac complex;

determining a degree of correlation between the at least one cardiac complex and at least one of the first and second morphological templates;

declaring one of a first and second rhythm state at least in part using the determined degree of correlation; and

updating the second morphological template if the cardiac complex is not sufficiently correlated to at least one of the first and second morphological templates.

21. A system comprising:

means for obtaining a first reference morphological template from a subject'"'"'s heart in the absence of an arrhythmia, while the subject is resting or inactive;

means for obtaining a second reference morphological template from the heart under a condition different from that of the first morphological template;

means for obtaining at least one current cardiac complex;

means for determining a degree of correlation between the at least one cardiac complex and at least one of the first and second morphological templates;

means for declaring one of first and second rhythm states at least in part using the determined degree of correlation; and

means for updating at least one of the first and second morphological templates.