Method and apparatus for improved vascular related treatment

• US 7,540,869 B2
• Filed: 12/27/2002
• Issued: 06/02/2009
• Est. Priority Date: 12/27/2001
• Status: Expired due to Term

• Current Assignee: Palomar Medical Technologies Incorporated (Hologic Incorporated)
• Original Assignee: Palomar Medical Technologies Incorporated (Hologic Incorporated)
• Inventors: Smirnov, Michael Z., Altshuler, Gregory B.
• Primary Examiner(s): Farah; Ahmed M
• Application Number:
  US10/331,134
• Publication Number:
  US 20040010298A1
• Time in Patent Office: 2,349 Days
• Field of Search: 606/3, 606 7- 9, 606/15, 607 88- 92, 607/94, 128/898
• US Class Current: 606/9
• CPC Class Codes: A61B 18/203 applying laser energy to the outside of the body
• CPC Class Codes: A61B 2018/00452 Skin
• CPC Class Codes: A61B 2018/00458 Deeper parts of the skin, e.g. treatment of vascular disorders or port wine stains
• CPC Class Codes: A61B 2018/2075 mixing three wavelengths

Abstract

Methods and apparatus are provided for selectively heating blood vessels in a patients skin to effect a desired dermatological (medical or cosmetic) treatment. For shallow vessels, particularly plexus vessels and superficial vessels/veins, radiation is applied to the vessels involved in the treatment which includes substantial radiation in a blue band of approximately 380-450 nm. The invention also involves maximizing the radiation used for which the safety radio for the area being treated is greater then one and minimizing the radiation used for which the safety ratio is less then one. This generally involves, depending on the blood vessel involved in the treatment and the patient'"'"'s skin type, using radiation in one or more of a blue, green-yellow and near infrared wavelength band and filtering out radiation at other wavelengths, including radiation between the wavelength bands used.

Claims

1. A method for performing dermatological treatments on blood vessels at depths of less than about 0.5 mm by applying optical radiation through skin to a treatment area which includes substantial radiation having a safety ratio of approximately at least one in a blue wavelength band of approximately 380-450 nm to induce coagulation at a target blood vessel.

2. A method as claimed in claim 1 wherein the optical radiation is coherent radiation and is of a wavelength in a range of approximately 400-450 nm.

3. A method as claimed in claim 2 wherein the wavelength of the coherent optical radiation is approximately 420-440 nm.

4. A method as claimed in claim 1 wherein the optical radiation is non-coherent broadband radiation, and wherein the blue radiation is in a band from 380-450 nm.

5. A method as claimed in claim 1 including applying pressure to a patient'"'"'s skin to remove blood from blood vessels in an area of treatment above blood vessels for which treatment is desired.

6. A method as claimed in claim 1 including cooling a patient'"'"'s skin above an area of treatment.

7. A method for performing treatments involving blood vessels by:

providing a broad-band optical radiation source,

filtering radiation from said source to pass only wavelengths from said source providing a safety ratio which is approximately at least one, wherein said filtered radiation comprises at least two substantially separate wavelengths of light from distinct bands of radiation selected from the group consisting of at least one wavelength in a blue wavelength band of approximately 380-450 nm, at least one wavelength in a green-yellow wavelength band of approximately 500-610 nm, and at least one wavelength in an NIR band of approximately 800-1120 nm, and

applying filtered radiation from said source through skin to the blood vessels involved in the treatment.

8. A method as claimed in claim 7 wherein radiation filtered from said source includes radiation having a wavelength from approximately 610 nm to 800 nm.

9. A method as claimed in claim 7 wherein radiation filtered from said source includes radiation having a wavelength from approximately 610 nm to 900 nm.

10. A method as claimed in claim 7 wherein radiation filtered from said source includes radiation having a wavelength from approximately 450 nm to 500 nm.

11. A method as claimed in claim 7 wherein radiation filtered from said source includes radiation having a wavelength longer than 1120nm.

12. A method as claimed in claim 7 including cooling a patient'"'"'s skin above an area of treatment.

13. A method as claimed in claim 7 wherein the filtered radiation passed during said filtering step further includes radiation in a green-yellow wavelength band, wherein radiation between said blue band and said green-yellow band being filtered out.

14. A method as claimed in claim 7 wherein radiation passed during said filtering step includes radiation in an NIR wavelength band, radiation between said blue band, said green-yellow band and said NIR band being filtered out.

15. A method as claimed in claim 7 wherein radiation passed during said filtering step includes radiation in a blue wavelength band and radiation in an NIR wavelength band, at least some radiation between said bands being filtered out.

16. A method as claimed in claim 7 wherein radiation passed during said filtering step further includes radiation in a green-yellow wavelength band and radiation in an NIR wavelength band, radiation between said bands being filtered out.

17. Apparatus for performing dermatological treatments involving blood vessels including:

a broad-band optical radiation source;

a mechanism for filtering radiation from said source to pass only wavelengths from said source providing a safety ratio which is approximately at least one, wherein the mechanism for filtering is capable of passing at least two substantially separate wavelengths of light from distinct bands of radiation, wherein the wavelength bands are selected from the group consisting of at least one wavelength in a blue wavelength band of approximately 380-450 nm, at least one wavelength in a green-yellow wavelength band of approximately 500-610 nm, and at least one wavelength in an NIR wavelength band of approximately 800-1120 nm; and

a mechanism for applying filtered radiation from said source to the blood vessels involved in the treatment.

18. Apparatus as claimed in claim 17 wherein radiation filtered from said source by said mechanism for filtering includes radiation having a wavelength from approximately 610 nm to 800 nm.

19. Apparatus as claimed in claim 17 wherein radiation filtered from said source by said mechanism for filtering includes radiation having a wavelength from approximately 610 nm to 900 nm.

20. Apparatus as claimed in claim 17 wherein radiation filtered from said source by said filtering means includes radiation having a wavelength from approximately 450 nm to 500 nm.

21. Apparatus as claimed in claim 17 including a mechanism for applying pressure to a patient'"'"'s skin to remove blood from blood vessels in an area of treatment above blood vessels for which treatment is desired.

22. Apparatus as claimed in claim 17 including a mechanism for cooling a patient'"'"'s skin above an area of treatment.

23. Apparatus s claimed in claim 17 wherein radiation passed by said mechanism for filtering includes radiation in a blue wavelength band and radiation in a green-yellow wavelength band, radiation between said bands being filtered out.

24. Apparatus as claimed in claim 23 wherein radiation passed by said mechanism for filtering includes radiation in an NIR wavelength band, radiation between said green band and said NIR band being filtered out.

25. Apparatus as claimed in claim 17 wherein radiation passed by said mechanism for filtering includes radiation in a blue wavelength band and radiation in an near-infrared wavelength band, at least some radiation between said bands being filtered out.

26. Apparatus as claimed in claim 17 wherein radiation passed by said mechanism for filtering includes radiation in a green-yellow wavelength band and radiation in an near infrared wavelength band, radiation between said bands being filtered out.

27. A method for performing treatments involving blood vessels at depths of less than about 0.5 mm by:

providing a broad-band optical radiation source,

filtering radiation from said source to pass only wavelengths from said source providing a safety ratio which is approximately at least one, wherein the filtered wavelengths are within a blue wavelength band of approximately 380-450 nm,

applying pressure to a patient'"'"'s skin to remove blood from blood vessels in an area of treatment above blood vessels for which treatment is desired, and

applying the filtered radiation from said source through skin to the blood vessels involved in the treatment.

28. A method for performing dermatological treatments involving at least one of plexus blood vessels and superficial blood vessels by applying optical radiation to a treatment area which includes substantial radiation in a blue wavelength band of approximately 380-450 nm and applying a second band of optical radiation to the treatment area, wherein the second band comprises a green-yellow wavelength band of approximately 510-595 nm.

29. A method for performing dermatological treatments involving at least one of plexus blood vessels and superficial blood vessels by applying optical radiation to a treatment area which includes substantial radiation in a blue wavelength band of approximately 380-450 nm and applying a second band of optical radiation, wherein the second band comprises radiation of approximately 500-610 nm in a green-yellow band.

30. A method for performing dermatological treatments involving at least one of plexus blood vessels and superficial blood vessels by applying optical radiation to a treatment area which includes substantial radiation in a blue wavelength band of approximately 380-450 nm, applying a second band of optical radiation, wherein the second band comprises radiation of approximately 500-610 nm in a green-yellow band, and applying a third band of optical radiation, wherein the third band comprises radiation in an NIR band.

31. A method for performing treatments on blood vessels by:

providing a broad-band optical radiation source,

filtering radiation from said source to pass only selected wavelengths from said source which are in at least two separate bands, the bands selected from the group of a blue band of approximately 380-450 nm, a green-yellow band of approximately 500-610 nm, and a near infrared (NIR) band of approximately 800-1120 nm, at least some of the radiation in wavelengths between the passed radiation bands being filtered out, and

applying filtered radiation from the at least two bands, sequentially or simultaneously, through skin to the blood vessels involved in the treatment.

32. A method as claimed in claim 31 wherein radiation from all three of said bands are passed during said filtering step.

33. A method for performing treatments on veins by:

providing a broad-band optical radiation source,

filtering radiation from said source to pass only selected wavelengths from said source, wherein the selected wavelengths are selected from the group consisting of at least one wavelength in a blue wavelength band of approximately 380-450 nm, at least one wavelength in a green-yellow wavelength band of approximately 500-610 nm, and at least one wavelength in an MR band of approximately 800-1120 nm, the wavelengths and duration of the radiation being selected to provide substantially uniform heating of each vessel and to provide a safety ratio which is approximately at least one, and

applying filtered radiation from the blue, green-yellow or NIR bands, either sequentially or simultaneously, to the vessel involved in the treatment.

34. A method as claimed in claim 33 wherein radiation passed during said filtering step includes radiation in a green-yellow wavelength band and radiation in an NIR wavelength band, radiation between said bands being filtered out.

35. A method as claimed in claim 33 wherein the pulse duration is approximately 0.1 to 100 times the thermal relaxation time of the vessel involved in the treatment.

36. Apparatus for performing dermatological treatments on blood vessels including:

a broad-band optical radiation source;

a mechanism for filtering radiation from said source to pass only selected wavelengths from said source which are in at least two separate bands, the bands selected from the group of a blue band of approximately 380-450 nm, a green-yellow band of approximately 500-610 nm, and a near infrared (NIR) band of approximately 800-1120 nm, at least some of the radiation in wavelengths between the passed radiation bands being filtered out; and

a mechanism for applying filtered radiation from the at least two bands, sequentially or simultaneously, to the blood vessels involved in the treatment.

37. Apparatus as claimed in claim 36 wherein said mechanism for filtering passes radiation from all three of said bands.

38. Apparatus for performing dermatological treatments on blood vessels including:

a broad-band optical radiation source providing pulses of a selected duration;

a mechanism for filtering radiation from said source to pass only selected wavelengths from said source, the wavelengths and duration of the radiation being selected to provide substantially uniform heating of each vessel wherein the wavelengths are selected from the group consisting of at least one wavelength in a blue wavelength band of approximately 380-450 nm, at least one wavelength in a green-yellow wavelength band of approximately 500-610 nm, and at least one wavelength in an NIR band of approximately 800-1120 nm; and

a mechanism for applying filtered radiation from the wavelength bands, sequentially or simultaneously, to the vessels involved in the treatment.

39. Apparatus as claimed in claim 38 wherein radiation passed by said mechanism for filtering includes radiation in a green-yellow wavelength band and radiation in an NIR wavelength band, radiation between said bands being filtered out.

40. Apparatus as claimed in claim 38 wherein the pulse duration provided by said source is approximately 0.1 to 100 times the thermal relaxation time of the vessel involved in the treatment.