Method of extracting and evaluating paced heart beats using max-min transform analysis

• US 7,542,794 B1
• Filed: 05/24/2006
• Issued: 06/02/2009
• Est. Priority Date: 05/24/2005
• Status: Expired due to Fees

• Current Assignee: Infinite Biomedical Technologies, LLC
• Original Assignee: Infinite Biomedical Technologies, LLC
• Inventors: Zhang, Hongxuan, Thakor, Nitish V., Natarajan, Ananth
• Primary Examiner(s): Layno; Carl H
• Assistant Examiner(s): Stewart; Jennifer
• Application Number:
  US11/439,900
• Time in Patent Office: 1,105 Days
• Field of Search: 600/509, 600/510, 600/515, 600/516, 600/521, 607/27, 607/28
• US Class Current: 600/509
• CPC Class Codes: A61B 5/366 Detecting abnormal QRS complex, e.g. widening
• CPC Class Codes: A61B 5/7207 of noise induced by motion artifacts
• CPC Class Codes: A61N 1/37 Monitoring; Protecting
• CPC Class Codes: G06F 2218/08 Feature extraction

Abstract

Methods for identifying and extracting heart depolarization and repolarization in a paced heart. Certain methods also include identifying and analyzing particular features of at least one pacing spike and QRS waveform for heart beat characterization. These features may include signal changing speed and signal time interval (distance) of pacing spikes and QRS depolarization when pacing excitation is initialized.

Claims

1. A method of analyzing paced heart beats, comprising:

providing a paced ECG signal including at least one QRS depolarization region and at least one pacing spike;

analyzing the at least one QRS depolarization region and the at least one pacing spike using max-min transform analysis of the ECG signal; and

identifying a time position of the at least one pacing spike in the paced ECG signal based on the max-min transform analysis of the ECG signal

wherein the max-min transform analysis of the ECG signal includes;

a first distance value between one of the at least one pacing spikes and an R-wave of the QRS depolarization region;

a second distance value between a Q-wave portion of the QRS depolarization region and the R-wave portion of the QRS depolarization region;

a third distance value between the R-wave portion of the QRS depolarization region and an S-wave portion of the QRS depolarization region; and

comparing the first distance value to the greater of the second and third distance values, and if the first distance value is smaller, then identifying the signal as a false paced heart beat.

2. The method of claim 1, wherein the paced ECG signal is selected from the group consisting of a raw ECG signal and a differential ECG signal.

3. The method of claim 1, further comprising performing a differential transformation of the paced ECG signal prior to the analyzing.

4. The method of claim 1, wherein the paced ECG signal is selected from the group consisting of an internal cardiac signal and a body surface cardiac signal.

5. The method of claim 1, further comprising, after identifying the time position, removing the at least one pacing spike from the paced ECG signal to yield a non-paced signal.

6. The method of claim 5, further comprising performing QRS depolarization analysis of the non-paced signal.