Nasal devices
First Claim
1. A nasal delivery device for delivering at least one substance to a nasal cavity of a subject, including a delivery unit comprising:
- a nosepiece for fitting to a nostril of a subject;
a mouthpiece through which the subject in use exhales to close the oropharyngeal velum;
a breath analyzer configured to detect the concentration of at least one component in air exhaled during exhalation through the mouthpiece; and
a substance supply unit for supplying at least one substance into the nasal cavity through the nosepiece during exhalation through the mouthpiece, the substance supply unit including a control unit configured to control the same to control supply of the at least one substance in response to the detected concentration.
4 Assignments
0 Petitions
Accused Products
Abstract
A nasal delivery device for and a method of delivering at least one substance to a nasal cavity of a subject. The nasal delivery device and method includes a delivery unit comprising: a nosepiece for fitting to a nostril of a subject; a mouthpiece through which the subject in use exhales; a breath analyzer for analyzing the concentration of at least one component in exhaled air from an exhalation breath; and a substance supply unit for supply at least one substance, the substance supply unit including a control unit for controlling the same to control supply of at least one substance in response to the detected concentration.
131 Citations
43 Claims
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1. A nasal delivery device for delivering at least one substance to a nasal cavity of a subject, including a delivery unit comprising:
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a nosepiece for fitting to a nostril of a subject; a mouthpiece through which the subject in use exhales to close the oropharyngeal velum; a breath analyzer configured to detect the concentration of at least one component in air exhaled during exhalation through the mouthpiece; and a substance supply unit for supplying at least one substance into the nasal cavity through the nosepiece during exhalation through the mouthpiece, the substance supply unit including a control unit configured to control the same to control supply of the at least one substance in response to the detected concentration. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 36)
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16. A nasal delivery device for delivering at least one substance to a nasal cavity of a subject, including a delivery unit comprising:
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a nosepiece for fitting to a nostril of a subject; a mouthpiece through which the subject in use exhales to close the oropharyngeal velum; a breath analyzer configured to detect the concentration of at least one component in air exhaled during exhalation through the mouthpiece; a substance supply unit for supplying at least one substance into the nasal cavity through the nosepiece during exhalation through the mouthpiece, the substance supply unit including a control unit configured to control the same to control supply of the at least one substance in response to the detected concentration; and an outlet unit comprising; a nosepiece for fitting in the other, outlet nostril of the subject; and an exit flow analyzer configured to analyze the concentration of at least one component in an air flow exiting the outlet nostril. - View Dependent Claims (17)
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18. A method of delivering at least one substance to a nasal cavity of a subject, comprising the steps of:
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providing a delivery device including a delivery unit comprising a nosepiece for fitting to a nostril of subject, a mouthpiece through which the subject exhales, a breath analyzer configured to analyze the concentration of at least one component in exhaled air from an exhalation breath, and a substance supply unit for supplying at least one substance; actuating the substance supply unit to supply at least one substance; and
controlling supply of the at least one substance by the substance supply unit in response to a concentration as detected by the breath analyzer. - View Dependent Claims (19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 37)
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32. A method of delivering at least one substance to a nasal cavity of a subject, comprising the steps:
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providing a delivery device including a delivery unit comprising a nosepiece for fitting to a nostril of a subject, a mouthpiece through which the subject exhales, a breath analyzer configuration to analyze the concentration of at least one component in exhaled air from an exhalation breath, and a substance supply unit for supplying at least one substance; actuating the substance supply unit to supply at least one substance; and
controlling supply of the at least one substance by the substance supply unit in response to a concentration as detected by the breathe analyzer;wherein the delivery device further includes an outlet unit comprising a nosepiece for fitting in the other, outlet nostril of the subject, and an exit flow configured to analyze the concentration of at least one component in an air flow exiting the outlet nostril. - View Dependent Claims (33, 34, 35)
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38. A nasal delivery device for delivering at least one substance to a nasal cavity of a subject, comprising:
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a first nosepiece for fitting to one, inlet nostril of a subject; a second nosepiece for fitting to the other, outlet nostril of the subject; a mouthpiece through which the subject in use exhales to close the oropharyngeal velum; an exit flow analyzer configured to analyze the concentration of at least one component in an air flow exiting the outlet nostril; and a substance supply unit for supplying at least one substance, the substance supply unit including a control unit configured to control the same to control supply of the at least one substance in response to a detected concentration. - View Dependent Claims (39)
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40. A method of delivering at least one substance to a nasal cavity of a subject, comprising the steps of:
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providing a delivery device including a delivery unit comprising a first nosepiece for fitting to one, inlet nostril of a subject, a mouthpiece through which the subject exhales, and a substance supply unit for supplying at least one substance, and an outlet unit comprising a second nosepiece for fitting to the other, outlet nostril of the subject, and an exit flow analyzer configured to analyze the concentration of at least one component in an air flow exiting the outlet nostril; actuating the substance supply unit to supply at least one substance; and controlling supply of the at least one substance by the substance supply unit in response to a concentration as detected by the exit flow analyzer. - View Dependent Claims (41, 42, 43)
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Specification