MCH receptor antagonists

• US 7,544,690 B2
• Filed: 09/30/2002
• Issued: 06/09/2009
• Est. Priority Date: 10/01/2001
• Status: Expired due to Fees

• Current Assignee: Taisho Pharmaceutical Company Limited (Taisho Pharmaceutical Holdings Company Limited)
• Original Assignee: Taisho Pharmaceutical Company Limited (Taisho Pharmaceutical Holdings Company Limited)
• Inventors: Kramer, Bryan Aubrey, Tran, Thuy-Anh, Beeley, Nigel Robert Arnold, Sekiguchi, Yoshinori, Kanuma, Kosuke, Omodera, Katsunori
• Primary Examiner(s): Balasubram; Venkataraman
• Application Number:
  US10/490,996
• Publication Number:
  US 20070037836A1
• Time in Patent Office: 2,444 Days
• Field of Search: 544/291, 544/111, 514/266.1, 514/231.5
• US Class Current: 514/266.1
• CPC Class Codes: A61P 25/22 Anxiolytics
• CPC Class Codes: A61P 25/24 Antidepressants
• CPC Class Codes: A61P 3/04 Anorexiants; Antiobesity agents
• CPC Class Codes: A61P 43/00 Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
• CPC Class Codes: C07D 239/95 with hetero atoms directly attached in positions 2 and 4
• CPC Class Codes: C07D 401/12 linked by a chain containing hetero atoms as chain links
• CPC Class Codes: C07D 403/12 linked by a chain containing hetero atoms as chain links
• CPC Class Codes: C07D 405/12 linked by a chain containing hetero atoms as chain links
• CPC Class Codes: C07D 409/12 linked by a chain containing hetero atoms as chain links
• CPC Class Codes: C07D 413/12 linked by a chain containing hetero atoms as chain links
• CPC Class Codes: C07D 417/12 linked by a chain containing hetero atoms as chain links

Abstract

The present invention relates to novel compounds of the formula (I) which act as MCH receptor antagonists. These compositions are useful in pharmaceutical compositions whose use includes prophylaxis or treatment of obesity, obesity related disorders, anxiety, or depression.

Claims

1. A compound selected from the group consisting of

2. A compound selected from the group consisting of

3. A compound selected from the group consisting of

4. A compound selected from the group consisting of