Arterial spin labeling with pulsed radio frequency sequences
First Claim
1. A method for imaging fluid flow and/or perfusion using spin labeling, the method comprising:
- applying a first magnetic gradient sequence to a labeling region;
applying a first pulsed radio frequency (RF) sequence to the labeling region continuously to label the fluid, the first pulsed RF sequence comprising a first plurality of pulses wherein an amplitude envelope is non-zero, the first plurality of pulses comprising at least five pulses, the first plurality of pulses each separated by a respective first plurality of intervals wherein the amplitude envelope is substantially zero; and
acquiring at least one first signal emitted from an imaging region, the acquisition of the at least one first signal being performed after a first delay interval after applying the first pulsed RF sequence.
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Abstract
In one aspect, a method for imaging fluid flow and/or perfusion using spin labeling is provided. The method comprises applying a first magnetic gradient sequence at least to a labeling region, applying a first pulsed radio frequency (RF) sequence to the labeling region to label the fluid, the first pulsed RF sequence comprising a first plurality of pulses wherein an amplitude envelope is non-zero, the first plurality of pulses each separated by a respective first plurality of intervals wherein the amplitude envelope is substantially zero, and acquiring at least one first signal emitted from an imaging region a predetermined delay after applying the first pulsed RF sequence.
21 Citations
20 Claims
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1. A method for imaging fluid flow and/or perfusion using spin labeling, the method comprising:
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applying a first magnetic gradient sequence to a labeling region; applying a first pulsed radio frequency (RF) sequence to the labeling region continuously to label the fluid, the first pulsed RF sequence comprising a first plurality of pulses wherein an amplitude envelope is non-zero, the first plurality of pulses comprising at least five pulses, the first plurality of pulses each separated by a respective first plurality of intervals wherein the amplitude envelope is substantially zero; and acquiring at least one first signal emitted from an imaging region, the acquisition of the at least one first signal being performed after a first delay interval after applying the first pulsed RF sequence. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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11. A magnetic resonance imaging apparatus adapted to perform fluid flow/perfusion imaging, the magnetic resonance imaging apparatus comprising:
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a first signal generator adapted to provide a first pulsed RF sequence continuously, the first pulsed RF sequence comprising a first plurality of pulses wherein an amplitude envelope is non-zero, the first plurality of pulses comprising at least five pulses, the first plurality of pulses each separated by a respective first plurality of intervals wherein the amplitude envelope is substantially zero; a second signal generator adapted to provide a first magnetic gradient sequence; at least one detector adapted to obtain signals emitted from an imaging region of an object of interest; at least one controller coupled to the first signal generator, the second signal generator and the at least one detector, the at least one controller adapted to perform a labeling procedure by controlling the first signal generator and the second signal generator to simultaneously provide the first pulsed RF sequence and the first magnetic gradient sequence for a labeling interval, and controlling the at least one detector to obtain at least one first signal after a first delay interval after the first labeling interval. - View Dependent Claims (12, 13, 14, 15, 16, 17, 18, 19, 20)
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Specification