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Optical apparatus and method of use for non-invasive tomographic scan of biological tissues

  • US 7,551,950 B2
  • Filed: 06/29/2004
  • Issued: 06/23/2009
  • Est. Priority Date: 06/29/2004
  • Status: Expired due to Fees
First Claim
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1. A method for quantifying at least one of scattering property, absorption coefficient or chromophore concentrations of a physical medium, said method comprising the steps of:

  • (a) using a wave source, introducing into said physical medium, at a first site, an input modulated signal with a modulation frequency (Fn);

    (b) using a wave detector, detecting, at a second site, an output modulated signal migrated over a migration path in said physical medium from said input modulated signal;

    (c) comparing said output modulated signal with said input modulated signal and measuring therefrom a phase shift (φ

    ) between said input modulated signal and said output modulated signal;

    (d) repeating steps (a)-(c) at two or more modulation frequencies and calculating an average scattering property and absorption coefficient of said physical medium using the following equation;

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